PDBsum entry 2sns

Hydrolase (phosphoric diester)

PDB id: 2sns

Contents

Protein chain

141 a.a. *

Ligands

THP

Metals

_CA

* Residue conservation analysis

PDB id:

2sns

Name:

Hydrolase (phosphoric diester)

Title:

Staphylococcal nuclease. Proposed mechanism of action based on structure of enzyme-thymidine 3(prime),5(prime)-biphosphate-calcium ion complex at 1.5-angstroms resolution

Structure:

Thermonuclease precursor. Chain: a. Engineered: yes

Source:

Staphylococcus aureus. Organism_taxid: 1280

Resolution:

1.50Å R-factor: not given

Authors:

M.J.Legg,F.A.Cotton,E.E.Hazen Jr.

Key ref:

F.A.Cotton et al. Thesis, Texas agricultural, .

Date:

14-May-82 Release date: 29-Jul-82

Supersedes:

1sns

Protein chain

P00644  (NUC_STAAU) -  Thermonuclease from Staphylococcus aureus

Seq: 231 a.a.

Struc: 141 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.3.1.31.1 - micrococcal nuclease.
• Reaction: Endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotide end-products.