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 | | Signaling protein/transferase
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2qme |
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*
Residue conservation analysis
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| PDB id: |
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2qme
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| Name: |
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Signaling protein/transferase
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| Title: |
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Crystal structure of human rac3 in complex with crib domain of human p21-activated kinase 1 (pak1)
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 Structure: |
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Ras-related c3 botulinum toxin substrate 3. Chain: a. Synonym: p21-rac3. Engineered: yes. Crib domain of the serine/threonine-protein kinase pak 1. Chain: i. Fragment: crib domain. Synonym: p21-activated kinase 1, pak-1, p65-pak, alpha-pak.
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: rac3. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthetic peptide with the sequence of the crib domain of human pak1 protein
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UniProt:
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| Seq: |
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192 a.a. |
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| Struc: |
178 a.a.* |
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545 a.a. |
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| Struc: |
24 a.a. |
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| Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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* PDB and UniProt seqs differ
at 1 residue position (black
cross)
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Enzyme class:
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Chain I:
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Reaction:
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ATP + a protein = ADP + a phosphoprotein
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Resolution:
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1.75Å
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R-factor:
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0.151
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R-free:
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0.192
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Authors:
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E.Ugochukwu,X.Yang,J.M.Elkins,N.Burgess-Brown,G.Bunkoczi, M.Sundstrom,C.H.Arrowsmith,J.Weigelt,A.Edwards,F.Von Delft, S.Knapp,D.Doyle,Structural Genomics Consortium (Sgc)
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Key ref:
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e.ugochukwu
et al.
the crystal structure of the human rac3 in complex with the crib domain of human p21-activated kinase 1 (pak1)..
TO BE PUBLISHED,
.
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Date:
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16-Jul-07
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Release date:
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28-Aug-07
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Related entries:
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crystal structure of human rac3 in complex with gdp and
chlorine
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