spacer
spacer

PDBsum entry 2q05

Go to PDB code: 
protein Protein-protein interface(s) links
Hydrolase PDB id
2q05
Jmol
Contents
Protein chains
181 a.a. *
172 a.a. *
Waters ×63
* Residue conservation analysis
PDB id:
2q05
Name: Hydrolase
Title: Crystal structure of tyr/ser protein phosphatase from vaccin wr
Structure: Dual specificity protein phosphatase. Chain: a, b, c, d. Synonym: late protein h1. Engineered: yes
Source: Vaccinia virus wr. Organism_taxid: 10254. Strain: wr (western reserve), vacv. Gene: h1l, vacwr099. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Resolution:
2.57Å     R-factor:   0.193     R-free:   0.218
Authors: J.Osipiuk,T.Skarina,O.Kagan,A.Savchenko,A.Edwards,A.Joachimi Midwest Center For Structural Genomics (Mcsg)
Key ref: J.Osipiuk et al. Crystal structure of tyr/ser protein phosphatase from vaccinia virus wr.. To be published, .
Date:
18-May-07     Release date:   19-Jun-07    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
P07239  (DUSP_VACCW) -  Dual specificity protein phosphatase H1
Seq:
Struc:
171 a.a.
181 a.a.*
Protein chain
Pfam   ArchSchema ?
P07239  (DUSP_VACCW) -  Dual specificity protein phosphatase H1
Seq:
Struc:
171 a.a.
172 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 2 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: Chains A, B, C, D: E.C.3.1.3.48  - Protein-tyrosine-phosphatase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Protein tyrosine phosphate + H2O = protein tyrosine + phosphate
Protein tyrosine phosphate
+ H(2)O
= protein tyrosine
+ phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     virion   2 terms 
  Biological process     viral reproduction   8 terms 
  Biochemical function     protein binding     6 terms