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protein ligands metals Protein-protein interface(s) links
Lyase PDB id
2pc9
Jmol
Contents
Protein chains
515 a.a. *
Ligands
PO4 ×16
ATP ×4
Metals
_CA ×4
Waters ×763
* Residue conservation analysis
PDB id:
2pc9
Name: Lyase
Title: Crystal structure of atp-dependent phosphoenolpyruvate carbo from thermus thermophilus hb8
Structure: Phosphoenolpyruvate carboxykinase [atp]. Chain: a, b, c, d. Synonym: pep carboxykinase, phosphoenolpyruvate carboxylase engineered: yes
Source: Thermus thermophilus. Organism_taxid: 300852. Strain: hb8. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Resolution:
2.40Å     R-factor:   0.213     R-free:   0.250
Authors: M.Sugahara,N.Kunishima,Riken Structural Genomics/proteomics Initiative (Rsgi)
Key ref: M.Sugahara and n.kunishima Crystal structure of atp-Dependent phosphoenolpyruvate carboxykinase from thermus thermophilus hb8. To be published,
Date:
29-Mar-07     Release date:   02-Oct-07    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q5SLL5  (PCKA_THET8) -  Phosphoenolpyruvate carboxykinase [ATP]
Seq:
Struc: 		 
Seq:
Struc: 		529 a.a.
515 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.4.1.1.49  - Phosphoenolpyruvate carboxykinase (ATP).
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: ATP + oxaloacetate = ADP + phosphoenolpyruvate + CO2
ATP
Bound ligand (Het Group name = ATP)
corresponds exactly 		+ oxaloacetate
 = ADP
 +
phosphoenolpyruvate
Bound ligand (Het Group name = PO4)
matches with 50.00% similarity 		+ CO(2)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cytoplasm   1 term 
  Biological process     gluconeogenesis   1 term 
  Biochemical function     nucleotide binding     8 terms