spacer
spacer

PDBsum entry 2pbc

Go to PDB code: 
protein ligands Protein-protein interface(s) links
Isomerase PDB id
2pbc
Jmol
Contents
Protein chains
100 a.a. *
Ligands
PEG ×4
Waters ×301
* Residue conservation analysis
PDB id:
2pbc
Name: Isomerase
Title: Fk506-binding protein 2
Structure: Fk506-binding protein 2. Chain: a, b, c, d. Fragment: residues 43-142. Synonym: peptidyl-prolyl cis-trans isomerase, ppiase, rotamase, 13 kda fkbp, fkbp-13. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fkbp2, fkbp13. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Resolution:
1.80Å     R-factor:   0.189     R-free:   0.260
Authors: J.R.Walker,D.Neculai,T.Davis,C.Butler-Cole,F.Sicheri, J.Weigelt,M.Sundstrom,C.H.Arrowsmith,A.M.Edwards, A.Bochkarev,S.Dhe-Paganon,Structural Genomics Consortium (Sgc)
Key ref: J.R.Walker et al. Structure of fk506-Binding protein 2. To be published, .
Date:
28-Mar-07     Release date:   10-Apr-07    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
P26885  (FKBP2_HUMAN) -  Peptidyl-prolyl cis-trans isomerase FKBP2
Seq:
Struc:
142 a.a.
100 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 2 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: E.C.5.2.1.8  - Peptidylprolyl isomerase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Peptidylproline (omega=180) = peptidylproline (omega=0)
Peptidylproline (omega=180)
= peptidylproline (omega=0)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     protein folding   1 term