spacer
spacer

PDBsum entry 2p31

Go to PDB code: 
protein metals Protein-protein interface(s) links
Oxidoreductase PDB id
2p31
Jmol
Contents
Protein chain
155 a.a. *
Metals
_CL ×2
Waters ×144
* Residue conservation analysis
PDB id:
2p31
Name: Oxidoreductase
Title: Crystal structure of human glutathione peroxidase 7
Structure: Glutathione peroxidase 7. Chain: a, b. Synonym: cl683. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gpx7, gpx6. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Resolution:
2.00Å     R-factor:   0.166     R-free:   0.215
Authors: K.L.Kavanagh,C.Johansson,E.Papagrigoriou,G.Kochan,C.Umeano,O F.Von Delft,J.Weigelt,C.H.Arrowsmith,M.Sundstrom,A.Edwards, U.Oppermann,Structural Genomics Consortium (Sgc)
Key ref: K.L.Kavanagh and u.oppermann Crystal structure of human glutathione peroxidase 7. To be published, .
Date:
08-Mar-07     Release date:   20-Mar-07    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q96SL4  (GPX7_HUMAN) -  Glutathione peroxidase 7
Seq:
Struc:
187 a.a.
155 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.1.11.1.9  - Glutathione peroxidase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: 2 glutathione + H2O2 = glutathione disulfide + 2 H2O
2 × glutathione
+ H(2)O(2)
= glutathione disulfide
+ 2 × H(2)O
      Cofactor: Se(2+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     extracellular region   3 terms 
  Biological process     oxidation-reduction process   2 terms 
  Biochemical function     oxidoreductase activity     3 terms