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* Residue conservation analysis
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PDB id:
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Transferase
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Title:
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Crystal structure of a polc-type DNA polymerase iii exonuclease domain from thermotoga maritima
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Structure:
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DNA polymerase iii polc-type. Chain: a, b. Fragment: exonuclease domain. Synonym: poliii. Engineered: yes
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Source:
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Thermotoga maritima msb8. Organism_taxid: 243274. Strain: msb8, dsm 3109, jcm 10099. Atcc: 43589. Gene: polc, tm_0576. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Resolution:
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2.50Å
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R-factor:
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0.232
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R-free:
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0.298
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Authors:
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J.B.Bonanno,M.Rutter,K.T.Bain,M.Izuka,V.Sridhar,D.Smith, S.Wasserman,M.J.Sauder,S.K.Burley,S.C.Almo,New York Sgx Research Center For Structural Genomics (Nysgxrc)
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Key ref:
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J.B.Bonanno
et al.
Crystal structure of a polc-Type DNA polymerase III exonuclease domain from thermotoga maritima.
To be published,
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Date:
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05-Mar-07
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Release date:
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20-Mar-07
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PROCHECK
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Headers
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References
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Q9ZHF6
(DPO3_THEMA) -
DNA polymerase III polC-type
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Seq:
Struc:
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1367 a.a.
164 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Enzyme class:
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E.C.2.7.7.7
- DNA-directed Dna polymerase.
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Reaction:
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Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
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Deoxynucleoside triphosphate
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+
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DNA(n)
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=
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diphosphate
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+
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DNA(n+1)
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Gene Ontology (GO) functional annotation
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Cellular component
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intracellular
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1 term
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Biological process
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DNA replication
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1 term
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Biochemical function
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nucleic acid binding
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4 terms
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Links
