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Hydrolase/hydrolase inhibitor
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PDB id
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2p0r
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Contents |
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* Residue conservation analysis
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PDB id:
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| Name: |
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Hydrolase/hydrolase inhibitor
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Title:
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Structure of human calpain 9 in complex with leupeptin
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Structure:
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Calpain-9. Chain: a, b. Fragment: minicalpain. Synonym: digestive tract-specific calpain. Ncl-4. Cg36 prot engineered: yes. Leupeptin. Chain: d, e. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: capn9, ncl4. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
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Resolution:
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2.50Å
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R-factor:
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0.213
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R-free:
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0.269
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Authors:
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T.L.Davis,R.Paramanathan,J.R.Walker,C.Butler-Cole,P.J.Finert J.Weigelt,M.Sundstrom,C.H.Arrowsmith,A.M.Edwards,A.Bochkare Paganon,Structural Genomics Consortium (Sgc)
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Key ref:
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T.L.Davis
et al.
Structures of human minicalpains bound to inhibitors.
To be published,
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Date:
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01-Mar-07
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Release date:
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20-Mar-07
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PROCHECK
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Headers
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References
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O14815
(CAN9_HUMAN) -
Calpain-9
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Seq:
Struc:
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690 a.a.
319 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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Gene Ontology (GO) functional annotation
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Cellular component
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intracellular
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1 term
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Biological process
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proteolysis
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1 term
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Biochemical function
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cysteine-type endopeptidase activity
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2 terms
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Links
