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PDBsum entry 2ozu
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Contents |
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* Residue conservation analysis
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PDB id:
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Transferase
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Title:
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Crystal structure of human myst histone acetyltransferase 3 in complex with acetylcoenzyme a
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Structure:
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Histone acetyltransferase myst3. Chain: a. Fragment: catalytic region: residues 497-780. Synonym: myst protein 3, moz, ybf2/sas3, sas2 and tip60 protein 3, runt-related transcription factor-binding protein 2, monocytic leukemia zinc finger protein, zinc finger protein 220. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: myst3, moz, runxbp2, znf220. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Resolution:
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2.30Å
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R-factor:
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0.193
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R-free:
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0.245
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Authors:
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J.Min,H.Wu,L.Dombrovski,G.Bernstein,A.Dong,P.Loppnau,J.Weigelt, M.Sundstrom,C.H.Arrowsmith,A.M.Edwards,A.Bochkarev,A.N.Plotnikov, Structural Genomics Consortium (Sgc)
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Key ref:
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H.Wu
et al.
The crystal structure of human myst histone acetyltransferase 3 in complex with acetylcoenzyme a.
To be published,
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Date:
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27-Feb-07
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Release date:
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13-Mar-07
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PROCHECK
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Headers
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References
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Q92794
(KAT6A_HUMAN) -
Histone acetyltransferase KAT6A from Homo sapiens
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Seq:
Struc:
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2004 a.a.
254 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 1 residue position (black
cross)
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Enzyme class:
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E.C.2.3.1.48
- histone acetyltransferase.
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Reaction:
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L-lysyl-[protein] + acetyl-CoA = N6-acetyl-L-lysyl-[protein] + CoA + H+
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L-lysyl-[protein]
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+
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acetyl-CoA
Bound ligand (Het Group name = )
corresponds exactly
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=
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N(6)-acetyl-L-lysyl-[protein]
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+
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CoA
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+
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H(+)
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
