PDBsum entry: 2ord

Transferase

PDB id: 2ord

Contents

Protein chains

393 a.a. *

Ligands

PLP ×2

GOL ×17

Waters ×675

* Residue conservation analysis

PDB id:

2ord

Name:

Transferase

Title:

Crystal structure of acetylornithine aminotransferase (ec 2. (Acoat) (tm1785) from thermotoga maritima at 1.40 a resolut

Structure:

Acetylornithine aminotransferase. Chain: a, b. Synonym: acoat. Engineered: yes

Source:

Thermotoga maritima msb8. Organism_taxid: 243274. Strain: msb8, dsm 3109, jcm 10099. Atcc: 43589. Gene: argd, tm1785. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.40Å R-factor: 0.149 R-free: 0.170

Authors:

Joint Center For Structural Genomics (Jcsg)

Key ref:

Joint center for structural genomics (jcsg) Crystal structure of acetylornithine aminotransferase (EC 2.6.1.11) (acoat) (tm1785) from thermotoga maritima at 1.40 a resolution. To be published,

Date:

02-Feb-07 Release date: 13-Feb-07

Protein chains

Q9X2A5  (ARGD_THEMA) -  Acetylornithine aminotransferase

Seq: 385 a.a.

Struc: 393 a.a.

Enzyme reactions

• Enzyme class: E.C.2.6.1.11 - Acetylornithine transaminase.
• Pathway: Ornithine Biosynthesis
• Reaction: N₂-acetyl-L-ornithine + 2-oxoglutarate = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate

N(2)-acetyl-L-ornithine + 2-oxoglutarate (Bound ligand (Het Group name = GOL) matches with 50.00% similarity) = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate

• Cofactor: Pyridoxal 5'-phosphate

Pyridoxal 5'-phosphate (Bound ligand (Het Group name = PLP) corresponds exactly)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 Gene Ontology (GO) functional annotation 

• Cellular component: cytoplasm (1 term)
• Biological process: cellular amino acid biosynthetic process (3 terms)
• Biochemical function: catalytic activity (5 terms)