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PDBsum entry 2ocs

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protein ligands links
Structural protein PDB id
2ocs
Jmol
Contents
Protein chain
85 a.a. *
Ligands
SCN
EDO
Waters ×91
* Residue conservation analysis
PDB id:
2ocs
Name: Structural protein
Title: The crystal structure of the first pdz domain of human nherf-2 (slc9a3r2)
Structure: Na(+)/h(+) exchange regulatory cofactor nhe-rf2. Chain: a. Synonym: nherf-2, tyrosine kinase activator protein 1, tka- 1, sry-interacting protein 1, sip-1, solute carrier family 9 isoform a3 regulatory factor 2, nhe3 kinase a regulatory protein e3karp, sodium-hydrogen exchanger regulatory factor 2. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: slc9a3r2, nherf2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Resolution:
1.50Å     R-factor:   0.154     R-free:   0.198
Authors: E.Papagrigoriou,C.Phillips,C.Gileadi,J.Elkins,E.Salah, G.Berridge,P.Savitsky,F.Gorrec,C.Umeano,E.Ugochukwu, O.Gileadi,N.Burgess,A.Edwards,C.H.Arrowsmith,J.Weigelt, M.Sundstrom,D.A.Doyle,Structural Genomics Consortium (Sgc)
Key ref: E.Papagrigoriou et al. The crystal structure of the first pdz domain of human nherf-2 (slc9a3r2). To be published, .
Date:
21-Dec-06     Release date:   16-Jan-07    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q15599  (NHRF2_HUMAN) -  Na(+)/H(+) exchange regulatory cofactor NHE-RF2
Seq:
Struc:
337 a.a.
85 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 5 residue positions (black crosses)