spacer
spacer

PDBsum entry 2oa7

Go to PDB code: 
protein ligands Protein-protein interface(s) links
Transferase PDB id
2oa7
Jmol
Contents
Protein chains
209 a.a. *
Ligands
GTX ×2
Waters ×233
* Residue conservation analysis
PDB id:
2oa7
Name: Transferase
Title: Mouse c14a glutathione-s-transferase mutant in complex with s-hexyl glutathione
Structure: Glutathione s-transferase p 1. Chain: a, b. Synonym: gst yf-yf, gst-pib, gst class-pi, gst p1, preadipocyte growth factor. Engineered: yes. Mutation: yes
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: gstp1, gstpib. Expressed in: escherichia coli. Expression_system_taxid: 562
Resolution:
2.20Å     R-factor:   0.217     R-free:   0.261
Authors: O.J.Kyrieleis,G.Mcmanus,T.J.Mantle,A.R.Khan
Key ref: O.J.Kyrieleis et al. Mouse c14a glutathione-S-Transferase mutant in complex with s-Hexyl glutathione. To be published, .
Date:
15-Dec-06     Release date:   30-Jan-07    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
P19157  (GSTP1_MOUSE) -  Glutathione S-transferase P 1
Seq:
Struc:
210 a.a.
209 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

 Enzyme reactions 
   Enzyme class: E.C.2.5.1.18  - Glutathione transferase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: RX + glutathione = HX + R-S-glutathione
RX
+
glutathione
Bound ligand (Het Group name = GTX)
matches with 76.00% similarity
= HX
+ R-S-glutathione
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     protein complex   7 terms 
  Biological process     metabolic process   38 terms 
  Biochemical function     drug binding     5 terms