PDBsum entry 2mys

Go to PDB code: 
protein ligands metals links
Muscle protein PDB id
Protein chains
800 a.a. *
138 a.a.* *
134 a.a.* *
* Residue conservation analysis
* C-alpha coords only
PDB id:
Name: Muscle protein
Title: Myosin subfragment-1, alpha carbon coordinates only for the two light chains
Structure: Myosin. Chain: a. Fragment: subfragment-1. Other_details: proteolytic fragment of myosin generated by papain digestion. Myosin. Chain: b. Fragment: subfragment-1. Other_details: proteolytic fragment of myosin generated by
Source: Gallus gallus. Chicken. Organism_taxid: 9031. Organ: skeletal. Tissue: pectoralis muscle. Tissue: pectoralis muscle
Biol. unit: Hexamer (from PDB file)
2.80Å     R-factor:   0.223    
Authors: I.Rayment,H.M.Holden
Key ref: I.Rayment et al. (1993). Three-dimensional structure of myosin subfragment-1: a molecular motor. Science, 261, 50-58. PubMed id: 8316857 DOI: 10.1126/science.8316857
27-Jun-96     Release date:   11-Jan-97    
Supersedes: 1mys
Go to PROCHECK summary

Protein chain
Pfam   ArchSchema ?
P13538  (MYSS_CHICK) -  Myosin heavy chain, skeletal muscle, adult
1939 a.a.
800 a.a.*
Protein chain
P02609  (MLRS_CHICK) -  Myosin regulatory light chain 2, skeletal muscle isoform
168 a.a.
138 a.a.*
Protein chain
P02604  (MLE1_CHICK) -  Myosin light chain 1, skeletal muscle isoform
192 a.a.
134 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 73 residue positions (black crosses)

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     myosin complex   1 term 
  Biochemical function     metal ion binding     4 terms  


    Added reference    
DOI no: 10.1126/science.8316857 Science 261:50-58 (1993)
PubMed id: 8316857  
Three-dimensional structure of myosin subfragment-1: a molecular motor.
I.Rayment, W.R.Rypniewski, K.Schmidt-Bäse, R.Smith, D.R.Tomchick, M.M.Benning, D.A.Winkelmann, G.Wesenberg, H.M.Holden.
Directed movement is a characteristic of many living organisms and occurs as a result of the transformation of chemical energy into mechanical energy. Myosin is one of three families of molecular motors that are responsible for cellular motility. The three-dimensional structure of the head portion of myosin, or subfragment-1, which contains both the actin and nucleotide binding sites, is described. This structure of a molecular motor was determined by single crystal x-ray diffraction. The data provide a structural framework for understanding the molecular basis of motility.

Literature references that cite this PDB file's key reference

  PubMed id Reference
23250061 W.A.Hendrickson (2013).
Evolution of diffraction methods for solving crystal structures.
  Acta Crystallogr A, 69, 51-59.  
21326200 C.Veigel, and C.F.Schmidt (2011).
Moving into the cell: single-molecule studies of molecular motors in complex environments.
  Nat Rev Mol Cell Biol, 12, 163-176.  
21415352 F.I.Malik, J.J.Hartman, K.A.Elias, B.P.Morgan, H.Rodriguez, K.Brejc, R.L.Anderson, S.H.Sueoka, K.H.Lee, J.T.Finer, R.Sakowicz, R.Baliga, D.R.Cox, M.Garard, G.Godinez, R.Kawas, E.Kraynack, D.Lenzi, P.P.Lu, A.Muci, C.Niu, X.Qian, D.W.Pierce, M.Pokrovskii, I.Suehiro, S.Sylvester, T.Tochimoto, C.Valdez, W.Wang, T.Katori, D.A.Kass, Y.T.Shen, S.F.Vatner, and D.J.Morgans (2011).
Cardiac myosin activation: a potential therapeutic approach for systolic heart failure.
  Science, 331, 1439-1443.  
21149681 J.H.Brown, V.S.Kumar, E.O'Neall-Hennessey, L.Reshetnikova, H.Robinson, M.Nguyen-McCarty, A.G.Szent-Györgyi, and C.Cohen (2011).
Visualizing key hinges and a potential major source of compliance in the lever arm of myosin.
  Proc Natl Acad Sci U S A, 108, 114-119.
PDB code: 3pn7
20938697 J.Tilsner, K.Amari, and L.Torrance (2011).
Plasmodesmata viewed as specialised membrane adhesion sites.
  Protoplasma, 248, 39-60.  
21482782 M.Reconditi, E.Brunello, M.Linari, P.Bianco, T.Narayanan, P.Panine, G.Piazzesi, V.Lombardi, and M.Irving (2011).
Motion of myosin head domains during activation and force development in skeletal muscle.
  Proc Natl Acad Sci U S A, 108, 7236-7240.  
20824688 N.Cohen-Hadar, S.Lagziel-Simis, Y.Wine, F.Frolow, and A.Freeman (2011).
Re-structuring protein crystals porosity for biotemplating by chemical modification of lysine residues.
  Biotechnol Bioeng, 108, 1.  
21428964 S.Pathmanathan, E.Hamilton, E.Atcheson, and D.J.Timson (2011).
The interaction of IQGAPs with calmodulin-like proteins.
  Biochem Soc Trans, 39, 694-699.  
20824272 V.Caorsi, D.S.Ushakov, T.G.West, N.Setta-Kaffetzi, and M.A.Ferenczi (2011).
FRET characterisation for cross-bridge dynamics in single-skinned rigor muscle fibres.
  Eur Biophys J, 40, 13-27.  
  21463317 W.Y.Chu, J.Chen, R.X.Zhou, F.L.Zhao, T.Meng, D.X.Chen, X.X.Nong, Z.Liu, S.Q.Lu, and J.S.Zhang (2011).
Characterization and ontogenetic expression analysis of the myosin light chains from the fast white muscle of mandarin fish Siniperca chuatsi.
  J Fish Biol, 78, 1225-1238.  
20386496 A.Doroszko, D.Polewicz, V.J.Cadete, J.Sawicka, M.Jones, D.Szczesna-Cordary, P.Y.Cheung, and G.Sawicki (2010).
Neonatal asphyxia induces the nitration of cardiac myosin light chain 2 that is associated with cardiac systolic dysfunction.
  Shock, 34, 592-600.  
20711642 A.Kengyel, W.A.Wolf, R.L.Chisholm, and J.R.Sellers (2010).
Nonmuscle myosin IIA with a GFP fused to the N-terminus of the regulatory light chain is regulated normally.
  J Muscle Res Cell Motil, 31, 163-170.  
20801044 A.Málnási-Csizmadia, and M.Kovács (2010).
Emerging complex pathways of the actomyosin powerstroke.
  Trends Biochem Sci, 35, 684-690.  
21152002 C.D.Williams, M.Regnier, and T.L.Daniel (2010).
Axial and radial forces of cross-bridges depend on lattice spacing.
  PLoS Comput Biol, 6, e1001018.  
21151434 D.I.Markov, E.O.Zubov, O.P.Nikolaeva, B.I.Kurganov, and D.I.Levitsky (2010).
Thermal denaturation and aggregation of Myosin subfragment 1 isoforms with different essential light chains.
  Int J Mol Sci, 11, 4194-4226.  
20035030 G.Y.Wang, C.C.Yeh, B.C.Jensen, M.J.Mann, P.C.Simpson, and A.J.Baker (2010).
Heart failure switches the RV alpha1-adrenergic inotropic response from negative to positive.
  Am J Physiol Heart Circ Physiol, 298, H913-H920.  
20192767 H.L.Sweeney, and A.Houdusse (2010).
Structural and functional insights into the Myosin motor mechanism.
  Annu Rev Biophys, 39, 539-557.  
19880375 H.Shishido, K.Nakazato, E.Katayama, S.Chaen, and S.Maruta (2010).
Kinesin-Calmodulin fusion protein as a molecular shuttle.
  J Biochem, 147, 213-223.  
20094053 J.A.Spudich, and S.Sivaramakrishnan (2010).
Myosin VI: an innovative motor that challenged the swinging lever arm hypothesis.
  Nat Rev Mol Cell Biol, 11, 128-137.  
20459085 J.J.Frye, V.A.Klenchin, C.R.Bagshaw, and I.Rayment (2010).
Insights into the importance of hydrogen bonding in the gamma-phosphate binding pocket of myosin: structural and functional studies of serine 236.
  Biochemistry, 49, 4897-4907.
PDB codes: 3myh 3myk 3myl
20080738 J.M.Laakso, J.H.Lewis, H.Shuman, and E.M.Ostap (2010).
Control of myosin-I force sensing by alternative splicing.
  Proc Natl Acad Sci U S A, 107, 698-702.  
20399183 M.Cecchini, Y.Alexeev, and M.Karplus (2010).
Pi release from myosin: a simulation analysis of possible pathways.
  Structure, 18, 458-470.  
20855589 M.J.Greenberg, K.Kazmierczak, D.Szczesna-Cordary, and J.R.Moore (2010).
Cardiomyopathy-linked myosin regulatory light chain mutations disrupt myosin strain-dependent biochemistry.
  Proc Natl Acad Sci U S A, 107, 17403-17408.  
20616041 M.Lorenz, and K.C.Holmes (2010).
The actin-myosin interface.
  Proc Natl Acad Sci U S A, 107, 12529-12534.  
20385833 M.Takano, T.P.Terada, and M.Sasai (2010).
Unidirectional Brownian motion observed in an in silico single molecule experiment of an actomyosin motor.
  Proc Natl Acad Sci U S A, 107, 7769-7774.  
20471271 R.E.McConnell, and M.J.Tyska (2010).
Leveraging the membrane - cytoskeleton interface with myosin-1.
  Trends Cell Biol, 20, 418-426.  
20399184 R.Tehver, and D.Thirumalai (2010).
Rigor to post-rigor transition in myosin V: link between the dynamics and the supporting architecture.
  Structure, 18, 471-481.  
20606261 S.Lara-González, J.J.Birktoft, and C.L.Lawson (2010).
Structure of the Escherichia coli RNA polymerase alpha subunit C-terminal domain.
  Acta Crystallogr D Biol Crystallogr, 66, 806-812.
PDB code: 3k4g
  20844746 S.Wu, J.Liu, M.C.Reedy, R.T.Tregear, H.Winkler, C.Franzini-Armstrong, H.Sasaki, C.Lucaveche, Y.E.Goldman, M.K.Reedy, and K.A.Taylor (2010).
Electron tomography of cryofixed, isometrically contracting insect flight muscle reveals novel actin-myosin interactions.
  PLoS One, 5, 0.
PDB codes: 2w49 2w4a 2w4g 2w4t
20226094 T.P.Burghardt, K.L.Neff, E.D.Wieben, and K.Ajtai (2010).
Myosin individualized: single nucleotide polymorphisms in energy transduction.
  BMC Genomics, 11, 172.  
20071392 T.Uno, T.Moriwaki, Y.Isoyama, Y.Uno, K.Kanamaru, H.Yamagata, M.Nakamura, and M.Takagi (2010).
Rab14 from Bombyx mori (Lepidoptera: Bombycidae) shows ATPase activity.
  Biol Lett, 6, 379-381.  
20385845 V.Nucciotti, C.Stringari, L.Sacconi, F.Vanzi, L.Fusi, M.Linari, G.Piazzesi, V.Lombardi, and F.S.Pavone (2010).
Probing myosin structural conformation in vivo by second-harmonic generation microscopy.
  Proc Natl Acad Sci U S A, 107, 7763-7768.  
20192763 W.Yang (2010).
Lessons learned from UvrD helicase: mechanism for directional movement.
  Annu Rev Biophys, 39, 367-385.  
19217860 A.Radocaj, T.Weiss, W.I.Helsby, B.Brenner, and T.Kraft (2009).
Force-generating cross-bridges during ramp-shaped releases: evidence for a new structural state.
  Biophys J, 96, 1430-1446.  
19506759 A.W.Serohijos, D.Tsygankov, S.Liu, T.C.Elston, and N.V.Dokholyan (2009).
Multiscale approaches for studying energy transduction in dynein.
  Phys Chem Chem Phys, 11, 4840-4850.  
19948121 B.Colombini, M.Nocella, G.Benelli, G.Cecchi, P.J.Griffiths, and M.A.Bagni (2009).
Reversal of the myosin power stroke induced by fast stretching of intact skeletal muscle fibers.
  Biophys J, 97, 2922-2929.  
19651039 B.Seebohm, F.Matinmehr, J.Köhler, A.Francino, F.Navarro-Lopéz, A.Perrot, C.Ozcelik, W.J.McKenna, B.Brenner, and T.Kraft (2009).
Cardiomyopathy mutations reveal variable region of myosin converter as major element of cross-bridge compliance.
  Biophys J, 97, 806-824.  
18980659 C.D.Leasure, E.Fiume, and J.C.Fletcher (2009).
The essential gene EMB1611 maintains shoot apical meristem function during Arabidopsis development.
  Plant J, 57, 579-592.  
19108638 D.A.Patel, and D.D.Root (2009).
Close proximity of myosin loop 3 to troponin determined by triangulation of resonance energy transfer distance measurements.
  Biochemistry, 48, 357-369.  
19416073 D.D.Thomas, D.Kast, and V.L.Korman (2009).
Site-directed spectroscopic probes of actomyosin structural dynamics.
  Annu Rev Biophys, 38, 347-369.  
19804726 D.Hyatt, R.Cooke, and E.Pate (2009).
Analysis of the interaction of the nucleotide base with myosin and the effect on substrate efficacy.
  Biophys J, 97, 1952-1960.  
19769984 D.M.Himmel, S.Mui, E.O'Neall-Hennessey, A.G.Szent-Györgyi, and C.Cohen (2009).
The on-off switch in regulated myosins: different triggers but related mechanisms.
  J Mol Biol, 394, 496-505.
PDB codes: 3jtd 3jvt
18945678 G.Bajaj, Y.Zhang, M.I.Schimerlik, A.M.Hau, J.Yang, T.M.Filtz, C.Kioussi, and J.E.Ishmael (2009).
N-methyl-D-aspartate receptor subunits are non-myosin targets of myosin regulatory light chain.
  J Biol Chem, 284, 1252-1266.  
19408946 K.Ajtai, M.F.Halstead, M.Nyitrai, A.R.Penheiter, Y.Zheng, and T.P.Burghardt (2009).
The myosin C-loop is an allosteric actin contact sensor in actomyosin.
  Biochemistry, 48, 5263-5275.  
19955408 K.Ito, Y.Yamaguchi, K.Yanase, Y.Ichikawa, and K.Yamamoto (2009).
Unique charge distribution in surface loops confers high velocity on the fast motor protein Chara myosin.
  Proc Natl Acad Sci U S A, 106, 21585-21590.  
19361417 K.Kazmierczak, Y.Xu, M.Jones, G.Guzman, O.M.Hernandez, W.G.Kerrick, and D.Szczesna-Cordary (2009).
The role of the N-terminus of the myosin essential light chain in cardiac muscle contraction.
  J Mol Biol, 387, 706-725.  
19470801 K.Pant, J.Watt, M.Greenberg, M.Jones, D.Szczesna-Cordary, and J.R.Moore (2009).
Removal of the cardiac myosin regulatory light chain increases isometric force production.
  FASEB J, 23, 3571-3580.  
18929571 M.J.Greenberg, J.D.Watt, M.Jones, K.Kazmierczak, D.Szczesna-Cordary, and J.R.Moore (2009).
Regulatory light chain mutations associated with cardiomyopathy affect myosin mechanics and kinetics.
  J Mol Cell Cardiol, 46, 108-115.  
19458282 M.J.Greenberg, T.R.Mealy, J.D.Watt, M.Jones, D.Szczesna-Cordary, and J.R.Moore (2009).
The molecular effects of skeletal muscle myosin regulatory light chain phosphorylation.
  Am J Physiol Regul Integr Comp Physiol, 297, R265-R274.  
19695097 R.M.Couñago, M.Davlieva, U.Strych, R.E.Hill, and K.L.Krause (2009).
Biochemical and structural characterization of alanine racemase from Bacillus anthracis (Ames).
  BMC Struct Biol, 9, 53.
PDB code: 3ha1
19966224 R.V.Agafonov, I.V.Negrashov, Y.V.Tkachev, S.E.Blakely, M.A.Titus, D.D.Thomas, and Y.E.Nesmelov (2009).
Structural dynamics of the myosin relay helix by time-resolved EPR and FRET.
  Proc Natl Acad Sci U S A, 106, 21625-21630.  
19106098 S.B.Scruggs, A.C.Hinken, A.Thawornkaiwong, J.Robbins, L.A.Walker, Tombe, D.L.Geenen, P.M.Buttrick, and R.J.Solaro (2009).
Ablation of ventricular myosin regulatory light chain phosphorylation in mice causes cardiac dysfunction in situ and affects neighboring myofilament protein phosphorylation.
  J Biol Chem, 284, 5097-5106.  
19635597 S.Ni, F.Hong, P.D.Brewer, M.Ikebe, H.Onishi, J.E.Baker, K.C.Facemyer, and C.R.Cremo (2009).
Kinetic and motor functions mediated by distinct regions of the regulatory light chain of smooth muscle myosin.
  Biochim Biophys Acta, 1794, 1599-1605.  
19127992 T.P.Burghardt, J.Li, and K.Ajtai (2009).
Single myosin lever arm orientation in a muscle fiber detected with photoactivatable GFP.
  Biochemistry, 48, 754-765.  
  19382535 T.S.Wong, B.Brough, and C.M.Ho (2009).
Creation of functional micro/nano systems through top-down and bottom-up approaches.
  Mol Cell Biomech, 6, 1.  
18987303 W.G.Kerrick, K.Kazmierczak, Y.Xu, Y.Wang, and D.Szczesna-Cordary (2009).
Malignant familial hypertrophic cardiomyopathy D166V mutation in the ventricular myosin regulatory light chain causes profound effects in skinned and intact papillary muscle fibers from transgenic mice.
  FASEB J, 23, 855-865.  
19756531 Z.Song, K.J.Parker, I.Enoh, H.Zhao, and O.Olubajo (2009).
Myosin-catalyzed ATP hydrolysis elucidated by 31P NMR kinetic studies and 1H PFG-diffusion measurements.
  Anal Bioanal Chem, 395, 1453-1459.  
19506755 d.e.l. .R.Jackson, and J.E.Baker (2009).
The energetics of allosteric regulation of ADP release from myosin heads.
  Phys Chem Chem Phys, 11, 4808-4814.  
18621839 A.C.Knowles, R.E.Ferguson, B.D.Brandmeier, Y.B.Sun, D.R.Trentham, and M.Irving (2008).
Orientation of the essential light chain region of myosin in relaxed, active, and rigor muscle.
  Biophys J, 95, 3882-3891.  
18957515 A.J.Engler, C.Carag-Krieger, C.P.Johnson, M.Raab, H.Y.Tang, D.W.Speicher, J.W.Sanger, J.M.Sanger, and D.E.Discher (2008).
Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating.
  J Cell Sci, 121, 3794-3802.  
18805936 A.R.Thompson, N.Naber, C.Wilson, R.Cooke, and D.D.Thomas (2008).
Structural dynamics of the actomyosin complex probed by a bifunctional spin label that cross-links SH1 and SH2.
  Biophys J, 95, 5238-5246.  
18544034 D.M.Milewicz, D.C.Guo, V.Tran-Fadulu, A.L.Lafont, C.L.Papke, S.Inamoto, C.S.Kwartler, and H.Pannu (2008).
Genetic basis of thoracic aortic aneurysms and dissections: focus on smooth muscle cell contractile dysfunction.
  Annu Rev Genomics Hum Genet, 9, 283-302.  
19325814 E.Grazi (2008).
Water and muscle contraction.
  Int J Mol Sci, 9, 1435-1452.  
18480297 E.P.Debold, S.E.Beck, and D.M.Warshaw (2008).
Effect of low pH on single skeletal muscle myosin mechanics and kinetics.
  Am J Physiol Cell Physiol, 295, C173-C179.  
18599626 F.Q.Zhao, R.Padrón, and R.Craig (2008).
Blebbistatin stabilizes the helical order of myosin filaments by promoting the switch 2 closed state.
  Biophys J, 95, 3322-3329.  
19325803 H.Tajsharghi (2008).
Thick and thin filament gene mutations in striated muscle diseases.
  Int J Mol Sci, 9, 1259-1275.  
18234833 I.Adamovic, S.M.Mijailovich, and M.Karplus (2008).
The elastic properties of the structurally characterized myosin II S2 subdomain: a molecular dynamics and normal mode analysis.
  Biophys J, 94, 3779-3789.  
19325727 I.Aprodu, A.Redaelli, and M.Soncini (2008).
Actomyosin interaction: mechanical and energetic properties in different nucleotide binding States.
  Int J Mol Sci, 9, 1927-1943.  
18211842 J.A.Spudich (2008).
Molecular motors: a surprising twist in myosin VI translocation.
  Curr Biol, 18, R68-R70.  
18725645 J.C.Klein, A.R.Burr, B.Svensson, D.J.Kennedy, J.Allingham, M.A.Titus, I.Rayment, and D.D.Thomas (2008).
Actin-binding cleft closure in myosin II probed by site-directed spin labeling and pulsed EPR.
  Proc Natl Acad Sci U S A, 105, 12867-12872.  
18931255 J.F.Beausang, H.W.Schroeder, P.C.Nelson, and Y.E.Goldman (2008).
Twirling of actin by myosins II and V observed via polarized TIRF in a modified gliding assay.
  Biophys J, 95, 5820-5831.  
18155233 J.H.Brown, Y.Yang, L.Reshetnikova, S.Gourinath, D.Süveges, J.Kardos, F.Hóbor, R.Reutzel, L.Nyitray, and C.Cohen (2008).
An unstable head-rod junction may promote folding into the compact off-state conformation of regulated myosins.
  J Mol Biol, 375, 1434-1443.
PDB codes: 3bas 3bat
18588896 K.P.Littlefield, A.B.Ward, J.S.Chappie, M.K.Reedy, S.I.Bernstein, R.A.Milligan, and M.C.Reedy (2008).
Similarities and differences between frozen-hydrated, rigor acto-S1 complexes of insect flight and chicken skeletal muscles.
  J Mol Biol, 381, 519-528.  
18951904 L.Alamo, W.Wriggers, A.Pinto, F.Bártoli, L.Salazar, F.Q.Zhao, R.Craig, and R.Padrón (2008).
Three-dimensional reconstruction of tarantula myosin filaments suggests how phosphorylation may regulate myosin activity.
  J Mol Biol, 384, 780-797.
PDB code: 3dtp
18326487 L.Liu, R.Srikakulam, and D.A.Winkelmann (2008).
Unc45 activates Hsp90-dependent folding of the myosin motor domain.
  J Biol Chem, 283, 13185-13193.  
18704171 M.Cecchini, A.Houdusse, and M.Karplus (2008).
Allosteric communication in myosin V: from small conformational changes to large directed movements.
  PLoS Comput Biol, 4, e1000129.  
18568345 M.J.Harris, and H.J.Woo (2008).
Energetics of subdomain movements and fluorescence probe solvation environment change in ATP-bound myosin.
  Eur Biophys J, 38, 1.  
18523008 M.Lord, T.E.Sladewski, and T.D.Pollard (2008).
Yeast UCS proteins promote actomyosin interactions and limit myosin turnover in cells.
  Proc Natl Acad Sci U S A, 105, 8014-8019.  
18757874 M.Rusu, S.Birmanns, and W.Wriggers (2008).
Biomolecular pleiomorphism probed by spatial interpolation of coarse models.
  Bioinformatics, 24, 2460-2466.  
18552179 M.Sun, M.B.Rose, S.K.Ananthanarayanan, D.J.Jacobs, and C.M.Yengo (2008).
Characterization of the pre-force-generation state in the actomyosin cross-bridge cycle.
  Proc Natl Acad Sci U S A, 105, 8631-8636.  
18598361 N.Walter, and C.L.Holweg (2008).
Head-neck domain of Arabidopsis myosin XI, MYA2, fused with GFP produces F-actin patterns that coincide with fast organelle streaming in different plant cells.
  BMC Plant Biol, 8, 74.  
17960418 O.Andruchov, and S.Galler (2008).
Influence of fast and slow alkali myosin light chain isoforms on the kinetics of stretch-induced force transients of fast-twitch type IIA fibres of rat.
  Pflugers Arch, 455, 1165-1172.  
19109888 R.S.Williams, G.J.Williams, and J.A.Tainer (2008).
A charged performance by gp17 in viral packaging.
  Cell, 135, 1169-1171.  
18478096 R.Srikakulam, L.Liu, and D.A.Winkelmann (2008).
Unc45b forms a cytosolic complex with Hsp90 and targets the unfolded myosin motor domain.
  PLoS ONE, 3, e2137.  
18765799 R.V.Agafonov, Y.E.Nesmelov, M.A.Titus, and D.D.Thomas (2008).
Muscle and nonmuscle myosins probed by a spin label at equivalent sites in the force-generating domain.
  Proc Natl Acad Sci U S A, 105, 13397-13402.  
18971336 S.Iwai, and T.Q.Uyeda (2008).
Visualizing myosin-actin interaction with a genetically-encoded fluorescent strain sensor.
  Proc Natl Acad Sci U S A, 105, 16882-16887.  
18494798 S.Ortiz-Costa, M.M.Sorenson, and M.Sola-Penna (2008).
Betaine protects urea-induced denaturation of myosin subfragment-1.
  FEBS J, 275, 3388-3396.  
18587628 S.Pathmanathan, S.F.Elliott, S.McSwiggen, B.Greer, P.Harriott, G.B.Irvine, and D.J.Timson (2008).
IQ motif selectivity in human IQGAP1: binding of myosin essential light chain and S100B.
  Mol Cell Biochem, 318, 43-51.  
18375581 T.J.Herron, E.J.Devaney, and J.M.Metzger (2008).
Modulation of cardiac performance by motor protein gene transfer.
  Ann N Y Acad Sci, 1123, 96.  
19325791 T.Mitsui, and H.Ohshima (2008).
Remarks on muscle contraction mechanism.
  Int J Mol Sci, 9, 872-904.  
18397183 T.Richter, M.Floetenmeyer, C.Ferguson, J.Galea, J.Goh, M.R.Lindsay, G.P.Morgan, B.J.Marsh, and R.G.Parton (2008).
High-resolution 3D quantitative analysis of caveolar ultrastructure and caveola-cytoskeleton interactions.
  Traffic, 9, 893-909.  
19325829 W.F.Widdas (2008).
A Reconsideration of the Link between the Energetics of Water and of ATP Hydrolysis Energy in the Power Strokes of Molecular Motors in Protein Structures.
  Int J Mol Sci, 9, 1730-1752.  
18339764 Y.E.Nesmelov, R.V.Agafonov, A.R.Burr, R.T.Weber, and D.D.Thomas (2008).
Structure and dynamics of the force-generating domain of myosin probed by multifrequency electron paramagnetic resonance.
  Biophys J, 95, 247-256.  
18619975 Y.Yang, H.Yu, and Q.Cui (2008).
Extensive conformational transitions are required to turn on ATP hydrolysis in myosin.
  J Mol Biol, 381, 1407-1420.  
18855436 Z.Zhang, and W.Wriggers (2008).
Coarse-graining protein structures with local multivariate features from molecular dynamics.
  J Phys Chem B, 112, 14026-14035.  
18159245 B.S.Budde, P.Binner, S.Waldmüller, W.Höhne, W.Blankenfeldt, S.Hassfeld, J.Brömsen, A.Dermintzoglou, M.Wieczorek, E.May, E.Kirst, C.Selignow, K.Rackebrandt, M.Müller, R.S.Goody, H.P.Vosberg, P.Nürnberg, and T.Scheffold (2007).
Noncompaction of the Ventricular Myocardium Is Associated with a De Novo Mutation in the beta-Myosin Heavy Chain Gene.
  PLoS ONE, 2, e1362.  
17287347 C.Hyeon, and J.N.Onuchic (2007).
Internal strain regulates the nucleotide binding site of the kinesin leading head.
  Proc Natl Acad Sci U S A, 104, 2175-2180.  
17502095 C.R.Bagshaw (2007).
Myosin mechanochemistry.
  Structure, 15, 511-512.  
17487252 F.R.Gil, and A.M.Lauzon (2007).
Smooth muscle molecular mechanics in airway hyperresponsiveness and asthma.
  Can J Physiol Pharmacol, 85, 133-140.  
17433365 H.Iwamoto, K.Oiwa, M.Kovács, J.R.Sellers, T.Suzuki, J.Wakayama, T.Tamura, N.Yagi, and T.Fujisawa (2007).
Diversity of structural behavior in vertebrate conventional myosins complexed with actin.
  J Mol Biol, 369, 249-264.  
17640901 H.Onishi, and M.F.Morales (2007).
A closer look at energy transduction in muscle.
  Proc Natl Acad Sci U S A, 104, 12714-12719.  
17666408 H.Pannu, V.Tran-Fadulu, C.L.Papke, S.Scherer, Y.Liu, C.Presley, D.Guo, A.L.Estrera, H.J.Safi, A.R.Brasier, G.W.Vick, A.J.Marian, C.S.Raman, L.M.Buja, and D.M.Milewicz (2007).
MYH11 mutations result in a distinct vascular pathology driven by insulin-like growth factor 1 and angiotensin II.
  Hum Mol Genet, 16, 2453-2462.  
17628590 J.Bosch, S.Turley, C.M.Roach, T.M.Daly, L.W.Bergman, and W.G.Hol (2007).
The closed MTIP-myosin A-tail complex from the malaria parasite invasion machinery.
  J Mol Biol, 372, 77-88.
PDB code: 2qac
17429832 K.Sugiura, K.Ohkawa, T.Hirai, and T.Fujii (2007).
ATPase-coupled release control from polyion complex capsules encapsulating muscle proteins.
  Macromol Biosci, 7, 508-516.  
17545237 L.M.Espinoza-Fonseca, D.Kast, and D.D.Thomas (2007).
Molecular dynamics simulations reveal a disorder-to-order transition on phosphorylation of smooth muscle myosin.
  Biophys J, 93, 2083-2090.  
17541712 L.Shakirova, V.Mikhailova, E.Siletskaya, V.P.Timofeev, and D.I.Levitsky (2007).
Nucleotide-induced and actin-induced structural changes in SH1-SH2-modified myosin subfragment 1.
  J Muscle Res Cell Motil, 28, 67-78.  
17956658 L.Zhu, D.Bonnet, M.Boussion, B.Vedie, D.Sidi, and X.Jeunemaitre (2007).
Investigation of the MYH11 gene in sporadic patients with an isolated persistently patent arterial duct.
  Cardiol Young, 17, 666-672.  
17704147 M.F.Halstead, K.Ajtai, A.R.Penheiter, J.D.Spencer, Y.Zheng, E.A.Morrison, and T.P.Burghardt (2007).
An unusual transduction pathway in human tonic smooth muscle myosin.
  Biophys J, 93, 3555-3566.  
18425593 M.Kawai, and H.R.Halvorson (2007).
Force transients and minimum cross-bridge models in muscular contraction.
  J Muscle Res Cell Motil, 28, 371-395.  
17142278 N.M.Kad, J.B.Patlak, P.M.Fagnant, K.M.Trybus, and D.M.Warshaw (2007).
Mutation of a conserved glycine in the SH1-SH2 helix affects the load-dependent kinetics of myosin.
  Biophys J, 92, 1623-1631.  
17028139 N.Naber, T.J.Purcell, E.Pate, and R.Cooke (2007).
Dynamics of the nucleotide pocket of myosin measured by spin-labeled nucleotides.
  Biophys J, 92, 172-184.  
17987111 N.Volkmann, H.Lui, L.Hazelwood, K.M.Trybus, S.Lowey, and D.Hanein (2007).
The R403Q Myosin Mutation Implicated in Familial Hypertrophic Cardiomyopathy Causes Disorder at the Actomyosin Interface.
  PLoS ONE, 2, e1123.  
17597155 S.Lowey, L.D.Saraswat, H.Liu, N.Volkmann, and D.Hanein (2007).
Evidence for an interaction between the SH3 domain and the N-terminal extension of the essential light chain in class II myosins.
  J Mol Biol, 371, 902-913.  
17910470 S.Manceva, T.Lin, H.Pham, J.H.Lewis, Y.E.Goldman, and E.M.Ostap (2007).
Calcium regulation of calmodulin binding to and dissociation from the myo1c regulatory domain.
  Biochemistry, 46, 11718-11726.  
17913331 T.P.Burghardt, J.Y.Hu, and K.Ajtai (2007).
Myosin dynamics on the millisecond time scale.
  Biophys Chem, 131, 15-28.  
17513376 T.P.Burghardt, K.Ajtai, D.K.Chan, M.F.Halstead, J.Li, and Y.Zheng (2007).
GFP-tagged regulatory light chain monitors single myosin lever-arm orientation in a muscle fiber.
  Biophys J, 93, 2226-2239.  
  17554174 W.Rauert, A.N.Eddine, S.H.Kaufmann, M.S.Weiss, and R.Janowski (2007).
Reductive methylation to improve crystallization of the putative oxidoreductase Rv0765c from Mycobacterium tuberculosis.
  Acta Crystallogr Sect F Struct Biol Cryst Commun, 63, 507-511.  
17504816 Y.Hachikubo, K.Ito, J.Schiefelbein, D.J.Manstein, and K.Yamamoto (2007).
Enzymatic activity and motility of recombinant Arabidopsis myosin XI, MYA1.
  Plant Cell Physiol, 48, 886-891.  
17502101 Y.Yang, S.Gourinath, M.Kovács, L.Nyitray, R.Reutzel, D.M.Himmel, E.O'Neall-Hennessey, L.Reshetnikova, A.G.Szent-Györgyi, J.H.Brown, and C.Cohen (2007).
Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor.
  Structure, 15, 553-564.
PDB codes: 2ec6 2ekv 2ekw 2os8 2otg 2ovk 2oy6 3i5f 3i5g 3i5h 3i5i
16470332 B.Brenner (2006).
The stroke size of myosins: a reevaluation.
  J Muscle Res Cell Motil, 27, 173-187.  
16907132 B.Geislinger, and R.Kawai (2006).
Brownian molecular motors driven by rotation-translation coupling.
  Phys Rev E Stat Nonlin Soft Matter Phys, 74, 011912.  
16785439 B.Guo, and W.H.Guilford (2006).
Mechanics of actomyosin bonds in different nucleotide states are tuned to muscle contraction.
  Proc Natl Acad Sci U S A, 103, 9844-9849.  
16933024 F.Vanzi, M.Capitanio, L.Sacconi, C.Stringari, R.Cicchi, M.Canepari, M.Maffei, N.Piroddi, C.Poggesi, V.Nucciotti, M.Linari, G.Piazzesi, C.Tesi, R.Antolini, V.Lombardi, R.Bottinelli, and F.S.Pavone (2006).
New techniques in linear and non-linear laser optics in muscle research.
  J Muscle Res Cell Motil, 27, 469-479.  
16603626 H.Onishi, S.V.Mikhailenko, and M.F.Morales (2006).
Toward understanding actin activation of myosin ATPase: the role of myosin surface loops.
  Proc Natl Acad Sci U S A, 103, 6136-6141.  
  16908724 J.E.Stelzer, J.R.Patel, and R.L.Moss (2006).
Acceleration of stretch activation in murine myocardium due to phosphorylation of myosin regulatory light chain.
  J Gen Physiol, 128, 261-272.  
16538438 J.H.Collins (2006).
Myoinformatics report: myosin regulatory light chain paralogs in the human genome.
  J Muscle Res Cell Motil, 27, 69-74.  
  16511258 J.Jiang, E.M.Lafer, and R.Sousa (2006).
Crystallization of a functionally intact Hsc70 chaperone.
  Acta Crystallogr Sect F Struct Biol Cryst Commun, 62, 39-43.  
  19946470 M.Reconditi (2006).
  Rep Prog Phys, 69, 2709-2759.  
17018783 N.M.Verrills, S.T.Po'uha, M.L.Liu, T.Y.Liaw, M.R.Larsen, M.T.Ivery, G.M.Marshall, P.W.Gunning, and M.Kavallaris (2006).
Alterations in gamma-actin and tubulin-targeted drug resistance in childhood leukemia.
  J Natl Cancer Inst, 98, 1363-1374.  
16614852 O.Andruchov, O.Andruchova, and S.Galler (2006).
Fine-tuning of cross-bridge kinetics in cardiac muscle of rat and mouse by myosin light chain isoforms.
  Pflugers Arch, 452, 667-673.  
16716643 R.Low, R.Léguillette, and A.M.Lauzon (2006).
(+)Insert smooth muscle myosin heavy chain (SM-B): from single molecule to human.
  Int J Biochem Cell Biol, 38, 1862-1874.  
16642020 R.M.Toydemir, A.Rutherford, F.G.Whitby, L.B.Jorde, J.C.Carey, and M.J.Bamshad (2006).
Mutations in embryonic myosin heavy chain (MYH3) cause Freeman-Sheldon syndrome and Sheldon-Hall syndrome.
  Nat Genet, 38, 561-565.  
17041932 R.M.Toydemir, H.Chen, V.K.Proud, R.Martin, H.van Bokhoven, B.C.Hamel, J.H.Tuerlings, C.A.Stratakis, L.B.Jorde, and M.J.Bamshad (2006).
Trismus-pseudocamptodactyly syndrome is caused by recurrent mutation of MYH8.
  Am J Med Genet A, 140, 2387-2393.  
16450056 S.Fujita-Becker, T.F.Reubold, and K.C.Holmes (2006).
The actin-binding cleft: functional characterisation of myosin II with a strut mutation.
  J Muscle Res Cell Motil, 27, 115-123.  
16547732 S.Nikolaou, M.Hu, N.B.Chilton, D.Hartman, A.J.Nisbet, P.J.Presidente, and R.B.Gasser (2006).
Isolation and characterization of class II myosin genes from Haemonchus contortus.
  Parasitol Res, 99, 200-203.  
16627942 T.J.Green, and M.Luo (2006).
Resolution improvement of X-ray diffraction data of crystals of a vesicular stomatitis virus nucleocapsid protein oligomer complexed with RNA.
  Acta Crystallogr D Biol Crystallogr, 62, 498-504.  
17178912 T.M.Huckaba, T.Lipkin, and L.A.Pon (2006).
Roles of type II myosin and a tropomyosin isoform in retrograde actin flow in budding yeast.
  J Cell Biol, 175, 957-969.  
17098187 T.S.Walter, C.Meier, R.Assenberg, K.F.Au, J.Ren, A.Verma, J.E.Nettleship, R.J.Owens, D.I.Stuart, and J.M.Grimes (2006).
Lysine methylation as a routine rescue strategy for protein crystallization.
  Structure, 14, 1617-1622.  
16404592 V.Azzu, D.Yadin, H.Patel, F.Fraternali, P.D.Chantler, and J.E.Molloy (2006).
Calcium regulates scallop muscle by changing myosin flexibility.
  Eur Biophys J, 35, 302-312.  
16645962 Y.Liu, M.Scolari, W.Im, and H.J.Woo (2006).
Protein-protein interactions in actin-myosin binding and structural effects of R405Q mutation: a molecular dynamics study.
  Proteins, 64, 156-166.  
16953301 Z.Y.Fu, B.T.Xie, Y.T.Ma, and Z.X.Gong (2006).
Preparation of monoclonal antibodies against human ventricular myosin light chain 1 (HVMLC1) for functional studies.
  Acta Biochim Biophys Sin (Shanghai), 38, 625-632.  
16075160 A.Málnási-Csizmadia, J.L.Dickens, W.Zeng, and C.R.Bagshaw (2005).
Switch movements and the myosin crossbridge stroke.
  J Muscle Res Cell Motil, 26, 31-37.  
16316347 A.Patzak, D.Petzhold, T.Wronski, P.Martinka, G.J.Babu, M.Periasamy, H.Haase, and I.Morano (2005).
Constriction velocities of renal afferent and efferent arterioles of mice are not related to SMB expression.
  Kidney Int, 68, 2726-2734.  
15951390 C.I.Robertson, D.P.Gaffney, L.R.Chrin, and C.L.Berger (2005).
Structural rearrangements in the active site of smooth-muscle myosin.
  Biophys J, 89, 1882-1892.  
16416041 D.W.Maughan (2005).
Kinetics and energetics of the crossbridge cycle.
  Heart Fail Rev, 10, 175-185.  
15766540 F.Fabiola, and M.S.Chapman (2005).
Fitting of high-resolution structures into electron microscopy reconstruction images.
  Structure, 13, 389-400.  
15886394 F.Xiao, W.D.Moll, S.Guo, and P.Guo (2005).
Binding of pRNA to the N-terminal 14 amino acids of connector protein of bacteriophage phi29.
  Nucleic Acids Res, 33, 2640-2649.  
15754360 J.Chaparro-Olaya, G.Margos, D.J.Coles, A.R.Dluzewski, G.H.Mitchell, M.M.Wasserman, and J.C.Pinder (2005).
Plasmodium falciparum myosins: transcription and translation during asexual parasite development.
  Cell Motil Cytoskeleton, 60, 200-213.  
15961426 M.Linari, E.Brunello, M.Reconditi, Y.B.Sun, P.Panine, T.Narayanan, G.Piazzesi, V.Lombardi, and M.Irving (2005).
The structural basis of the increase in isometric force production with temperature in frog skeletal muscle.
  J Physiol, 567, 459-469.  
15755919 M.Mishra, V.M.D'souza, K.C.Chang, Y.Huang, and M.K.Balasubramanian (2005).
Hsp90 protein in fission yeast Swo1p and UCS protein Rng3p facilitate myosin II assembly and function.
  Eukaryot Cell, 4, 567-576.  
16120677 M.Terrak, G.Rebowski, R.C.Lu, Z.Grabarek, and R.Dominguez (2005).
Structure of the light chain-binding domain of myosin V.
  Proc Natl Acad Sci U S A, 102, 12718-12723.
PDB code: 1n2d
16137617 N.Volkmann, H.Liu, L.Hazelwood, E.B.Krementsova, S.Lowey, K.M.Trybus, and D.Hanein (2005).
The structural basis of myosin V processive movement as revealed by electron cryomicroscopy.
  Mol Cell, 19, 595-605.  
15863618 S.Fischer, B.Windshügel, D.Horak, K.C.Holmes, and J.C.Smith (2005).
Structural mechanism of the recovery stroke in the myosin molecular motor.
  Proc Natl Acad Sci U S A, 102, 6873-6878.  
16143633 S.Galler, B.G.Wang, and M.Kawai (2005).
Elementary steps of the cross-bridge cycle in fast-twitch fiber types from rabbit skeletal muscles.
  Biophys J, 89, 3248-3260.  
15645163 T.Joseph, C.Coirault, O.Dubourg, and Y.Lecarpentier (2005).
Changes in crossbridge mechanical properties in diabetic rat cardiomyopathy.
  Basic Res Cardiol, 100, 231-239.  
15753305 W.D.Nelson, S.E.Blakely, Y.E.Nesmelov, and D.D.Thomas (2005).
Site-directed spin labeling reveals a conformational switch in the phosphorylation domain of smooth muscle myosin.
  Proc Natl Acad Sci U S A, 102, 4000-4005.  
15897189 X.Liu, S.Shu, M.Kovács, and E.D.Korn (2005).
Biological, biochemical, and kinetic effects of mutations of the cardiomyopathy loop of Dictyostelium myosin II: importance of ALA400.
  J Biol Chem, 280, 26974-26983.  
15103132 A.McPherson, J.Day, and L.J.Harris (2004).
Crystals of the beta-subunit of bovine luteinizing hormone and indicators for the involvement of proteolysis in protein crystallization.
  Acta Crystallogr D Biol Crystallogr, 60, 872-877.  
15041671 A.S.Brack, B.D.Brandmeier, R.E.Ferguson, S.Criddle, R.E.Dale, and M.Irving (2004).
Bifunctional rhodamine probes of Myosin regulatory light chain orientation in relaxed skeletal muscle fibers.
  Biophys J, 86, 2329-2341.  
15647168 A.V.Somlyo, A.S.Khromov, M.R.Webb, M.A.Ferenczi, D.R.Trentham, Z.H.He, S.Sheng, Z.Shao, and A.P.Somlyo (2004).
Smooth muscle myosin: regulation and properties.
  Philos Trans R Soc Lond B Biol Sci, 359, 1921-1930.  
15111417 B.A.Baumann, H.Liang, K.Sale, B.D.Hambly, and P.G.Fajer (2004).
Myosin regulatory domain orientation in skeletal muscle fibers: application of novel electron paramagnetic resonance spectral decomposition and molecular modeling methods.
  Biophys J, 86, 3030-3041.  
15014434 C.Batters, C.P.Arthur, A.Lin, J.Porter, M.A.Geeves, R.A.Milligan, J.E.Molloy, and L.M.Coluccio (2004).
Myo1c is designed for the adaptation response in the inner ear.
  EMBO J, 23, 1433-1440.  
15647165 C.Batters, M.I.Wallace, L.M.Coluccio, and J.E.Molloy (2004).
A model of stereocilia adaptation based on single molecule mechanical studies of myosin I.
  Philos Trans R Soc Lond B Biol Sci, 359, 1895-1905.  
15255774 C.Mavroidis, A.Dubey, and M.L.Yarmush (2004).
Molecular machines.
  Annu Rev Biomed Eng, 6, 363-395.  
15310845 C.Paolini, J.D.Fessenden, I.N.Pessah, and C.Franzini-Armstrong (2004).
Evidence for conformational coupling between two calcium channels.
  Proc Natl Acad Sci U S A, 101, 12748-12752.  
15630611 D.M.Warshaw (2004).
Lever arms and necks: a common mechanistic theme across the myosin superfamily.
  J Muscle Res Cell Motil, 25, 467-474.  
15579689 D.P.Kiehart, J.D.Franke, M.K.Chee, R.A.Montague, T.L.Chen, J.Roote, and M.Ashburner (2004).
Drosophila crinkled, mutations of which disrupt morphogenesis and cause lethality, encodes fly myosin VIIA.
  Genetics, 168, 1337-1352.  
15184651 D.Risal, S.Gourinath, D.M.Himmel, A.G.Szent-Györgyi, and C.Cohen (2004).
Myosin subfragment 1 structures reveal a partially bound nucleotide and a complex salt bridge that helps couple nucleotide and actin binding.
  Proc Natl Acad Sci U S A, 101, 8930-8935.
PDB codes: 1s5g 1sr6
15051736 E.S.Montana, and J.T.Littleton (2004).
Characterization of a hypercontraction-induced myopathy in Drosophila caused by mutations in Mhc.
  J Cell Biol, 164, 1045-1054.  
15473855 F.Buss, G.Spudich, and J.Kendrick-Jones (2004).
Myosin VI: cellular functions and motor properties.
  Annu Rev Cell Dev Biol, 20, 649-676.  
15502305 F.D.Schubot, and D.S.Waugh (2004).
A pivotal role for reductive methylation in the de novo crystallization of a ternary complex composed of Yersinia pestis virulence factors YopN, SycN and YscB.
  Acta Crystallogr D Biol Crystallogr, 60, 1981-1986.  
15750848 H.A.Al-Khayat, E.P.Morris, and J.M.Squire (2004).
Single particle analysis: a new approach to solving the 3D structure of myosin filaments.
  J Muscle Res Cell Motil, 25, 635-644.  
14742733 H.Fujita, X.Lu, M.Suzuki, S.Ishiwata, and M.Kawai (2004).
The effect of tropomyosin on force and elementary steps of the cross-bridge cycle in reconstituted bovine myocardium.
  J Physiol, 556, 637-649.  
15647159 H.L.Sweeney, and A.Houdusse (2004).
The motor mechanism of myosin V: insights for muscle contraction.
  Philos Trans R Soc Lond B Biol Sci, 359, 1829-1841.  
15044955 I.Lister, S.Schmitz, M.Walker, J.Trinick, F.Buss, C.Veigel, and J.Kendrick-Jones (2004).
A monomeric myosin VI with a large working stroke.
  EMBO J, 23, 1729-1738.  
14747987 I.Navizet, R.Lavery, and R.L.Jernigan (2004).
Myosin flexibility: structural domains and collective vibrations.
  Proteins, 54, 384-393.  
15189875 J.D.Lawson, E.Pate, I.Rayment, and R.G.Yount (2004).
Molecular dynamics analysis of structural factors influencing back door pi release in myosin.
  Biophys J, 86, 3794-3803.  
15256600 J.J.Sherwood, G.S.Waller, D.M.Warshaw, and S.Lowey (2004).
A point mutation in the regulatory light chain reduces the step size of skeletal muscle myosin.
  Proc Natl Acad Sci U S A, 101, 10973-10978.  
15630612 J.R.Sellers (2004).
Fifty years of contractility research post sliding filament hypothesis.
  J Muscle Res Cell Motil, 25, 475-482.  
15711883 J.Van Dijk, C.Lafont, M.L.Knetsch, J.Derancourt, D.J.Manstein, E.C.Long, and P.Chaussepied (2004).
Conformational changes in actin-myosin isoforms probed by Ni(II).Gly-Gly-His reactivity.
  J Muscle Res Cell Motil, 25, 527-537.  
15240477 J.Wakayama, T.Tamura, N.Yagi, and H.Iwamoto (2004).
Structural transients of contractile proteins upon sudden ATP liberation in skeletal muscle fibers.
  Biophys J, 87, 430-441.  
15647158 K.C.Holmes, R.R.Schröder, H.L.Sweeney, and A.Houdusse (2004).
The structure of the rigor complex and its implications for the power stroke.
  Philos Trans R Soc Lond B Biol Sci, 359, 1819-1828.  
15029249 K.Shipley, M.Hekmat-Nejad, J.Turner, C.Moores, R.Anderson, R.Milligan, R.Sakowicz, and R.Fletterick (2004).
Structure of a kinesin microtubule depolymerization machine.
  EMBO J, 23, 1422-1432.
PDB code: 1ry6
15100690 L.Craig, M.E.Pique, and J.A.Tainer (2004).
Type IV pilus structure and bacterial pathogenicity.
  Nat Rev Microbiol, 2, 363-378.  
15345555 M.van Duffelen, L.R.Chrin, and C.L.Berger (2004).
Nucleotide dependent intrinsic fluorescence changes of W29 and W36 in smooth muscle myosin.
  Biophys J, 87, 1767-1775.  
15510214 P.D.Coureux, H.L.Sweeney, and A.Houdusse (2004).
Three myosin V structures delineate essential features of chemo-mechanical transduction.
  EMBO J, 23, 4527-4537.
PDB codes: 1w7i 1w7j 1w8j
  15173218 R.Cooke (2004).
The sliding filament model: 1972-2004.
  J Gen Physiol, 123, 643-656.  
15647169 R.Roberts, I.Lister, S.Schmitz, M.Walker, C.Veigel, J.Trinick, F.Buss, and J.Kendrick-Jones (2004).
Myosin VI: cellular functions and motor properties.
  Philos Trans R Soc Lond B Biol Sci, 359, 1931-1944.  
  15199230 R.Vandenboom (2004).
The myofibrillar complex and fatigue: a review.
  Can J Appl Physiol, 29, 330-356.  
15647164 V.Lombardi, G.Piazzesi, M.Reconditi, M.Linari, L.Lucii, A.Stewart, Y.B.Sun, P.Boesecke, T.Narayanan, T.Irving, and M.Irving (2004).
X-ray diffraction studies of the contractile mechanism in single muscle fibres.
  Philos Trans R Soc Lond B Biol Sci, 359, 1883-1893.  
15630610 W.Lehman, R.Craig, and J.Hanson (2004).
The structure of the vertebrate striated muscle thin filament: a tribute to the contributions of Jean Hanson.
  J Muscle Res Cell Motil, 25, 455-466.  
15647160 W.Zeng, P.B.Conibear, J.L.Dickens, R.A.Cowie, S.Wakelin, A.Málnási-Csizmadia, and C.R.Bagshaw (2004).
Dynamics of actomyosin interactions in relation to the cross-bridge cycle.
  Philos Trans R Soc Lond B Biol Sci, 359, 1843-1855.  
14695277 X.Liu, and G.H.Pollack (2004).
Stepwise sliding of single actin and Myosin filaments.
  Biophys J, 86, 353-358.  
15111416 Y.S.Borovikov, I.V.Dedova, C.G.dos Remedios, N.N.Vikhoreva, P.G.Vikhorev, S.V.Avrova, T.L.Hazlett, and B.W.Van Der Meer (2004).
Fluorescence depolarization of actin filaments in reconstructed myofibers: the effect of S1 or pPDM-S1 on movements of distinct areas of actin.
  Biophys J, 86, 3020-3029.  
15647167 Y.Takagi, H.Shuman, and Y.E.Goldman (2004).
Coupling between phosphate release and force generation in muscle actomyosin.
  Philos Trans R Soc Lond B Biol Sci, 359, 1913-1920.  
12547786 A.Muhlrad, Y.M.Peyser, M.Nili, K.Ajtai, E.Reisler, and T.P.Burghardt (2003).
Chemical decoupling of ATPase activation and force production from the contractile cycle in myosin by steric hindrance of lever-arm movement.
  Biophys J, 84, 1047-1056.  
12975413 A.Woo, H.Rakowski, J.C.Liew, M.S.Zhao, C.C.Liew, T.G.Parker, M.Zeller, E.D.Wigle, and M.J.Sole (2003).
Mutations of the beta myosin heavy chain gene in hypertrophic cardiomyopathy: critical functional sites determine prognosis.
  Heart, 89, 1179-1185.  
12719468 D.Köhler, C.Ruff, E.Meyhöfer, and M.Bähler (2003).
Different degrees of lever arm rotation control myosin step size.
  J Cell Biol, 161, 237-241.  
14653810 E.Bódis, K.Szarka, M.Nyitrai, and B.Somogyi (2003).
Dynamic reorganization of the motor domain of myosin subfragment 1 in different nucleotide states.
  Eur J Biochem, 270, 4835-4845.  
12885653 H.A.AL-Khayat, L.Hudson, M.K.Reedy, T.C.Irving, and J.M.Squire (2003).
Myosin head configuration in relaxed insect flight muscle: x-ray modeled resting cross-bridges in a pre-powerstroke state are poised for actin binding.
  Biophys J, 85, 1063-1079.  
14507712 H.Iwamoto, J.Wakayama, T.Fujisawa, and N.Yagi (2003).
Static and dynamic x-ray diffraction recordings from living mammalian and amphibian skeletal muscles.
  Biophys J, 85, 2492-2506.  
12820213 H.R.Bergen, K.Ajtai, T.P.Burghardt, A.I.Nepomuceno, and D.C.Muddiman (2003).
Mass spectral determination of skeletal/cardiac actin isoform ratios in cardiac muscle.
  Rapid Commun Mass Spectrom, 17, 1467-1471.  
12808026 H.Toi, K.Fujimura-Kamada, K.Irie, Y.Takai, S.Todo, and K.Tanaka (2003).
She4p/Dim1p interacts with the motor domain of unconventional myosins in the budding yeast, Saccharomyces cerevisiae.
  Mol Biol Cell, 14, 2237-2249.  
12668452 J.Borejdo, and I.Akopova (2003).
Orientational changes of crossbridges during single turnover of ATP.
  Biophys J, 84, 2450-2459.  
14508495 K.C.Holmes, I.Angert, F.J.Kull, W.Jahn, and R.R.Schröder (2003).
Electron cryo-microscopy shows how strong binding of myosin to actin releases nucleotide.
  Nature, 425, 423-427.  
12885655 M.Reconditi, N.Koubassova, M.Linari, I.Dobbie, T.Narayanan, O.Diat, G.Piazzesi, V.Lombardi, and M.Irving (2003).
The conformation of myosin head domains in rigor muscle determined by X-ray interference.
  Biophys J, 85, 1098-1110.  
12554638 M.Terrak, G.Wu, W.F.Stafford, R.C.Lu, and R.Dominguez (2003).
Two distinct myosin light chain structures are induced by specific variations within the bound IQ motifs-functional implications.
  EMBO J, 22, 362-371.
PDB codes: 1m45 1m46
12679807 M.Xiao, J.G.Reifenberger, A.L.Wells, C.Baldacchino, L.Q.Chen, P.Ge, H.L.Sweeney, and P.R.Selvin (2003).
An actin-dependent conformational change in myosin.
  Nat Struct Biol, 10, 402-408.  
14532111 M.Yun, C.E.Bronner, C.G.Park, S.S.Cha, H.W.Park, and S.A.Endow (2003).
Rotation of the stalk/neck and one head in a new crystal structure of the kinesin motor protein, Ncd.
  EMBO J, 22, 5382-5389.
PDB code: 1n6m
12900396 N.M.Kad, A.S.Rovner, P.M.Fagnant, P.B.Joel, G.G.Kennedy, J.B.Patlak, D.M.Warshaw, and K.M.Trybus (2003).
A mutant heterodimeric myosin with one inactive head generates maximal displacement.
  J Cell Biol, 162, 481-488.  
12612343 N.Volkmann, G.Ouyang, K.M.Trybus, D.J.DeRosier, S.Lowey, and D.Hanein (2003).
Myosin isoforms show unique conformations in the actin-bound state.
  Proc Natl Acad Sci U S A, 100, 3227-3232.  
12668451 O.Roopnarine (2003).
Mechanical defects of muscle fibers with myosin light chain mutants that cause cardiomyopathy.
  Biophys J, 84, 2440-2449.  
14502269 P.B.Conibear, C.R.Bagshaw, P.G.Fajer, M.Kovács, and A.Málnási-Csizmadia (2003).
Myosin cleft movement and its coupling to actomyosin dissociation.
  Nat Struct Biol, 10, 831-835.  
14508494 P.D.Coureux, A.L.Wells, J.Ménétrey, C.M.Yengo, C.A.Morris, H.L.Sweeney, and A.Houdusse (2003).
A structural state of the myosin V motor without bound nucleotide.
  Nature, 425, 419-423.
PDB code: 1oe9
14513021 R.S.Goody (2003).
The missing link in the muscle cross-bridge cycle.
  Nat Struct Biol, 10, 773-775.  
14635256 S.A.Endow (2003).
Kinesin motors as molecular machines.
  Bioessays, 25, 1212-1219.  
14656445 S.Gourinath, D.M.Himmel, J.H.Brown, L.Reshetnikova, A.G.Szent-Györgyi, and C.Cohen (2003).
Crystal structure of scallop Myosin s1 in the pre-power stroke state to 2.6 a resolution: flexibility and function in the head.
  Structure, 11, 1621-1627.
PDB code: 1qvi
12517699 S.J.Winder (2003).
Structural insights into actin-binding, branching and bundling proteins.
  Curr Opin Cell Biol, 15, 14-22.  
14502270 T.F.Reubold, S.Eschenburg, A.Becker, F.J.Kull, and D.J.Manstein (2003).
A structural model for actin-induced nucleotide release in myosin.
  Nat Struct Biol, 10, 826-830.
PDB code: 1q5g
12944289 T.Yamada, Y.Takezawa, H.Iwamoto, S.Suzuki, and K.Wakabayashi (2003).
Rigor-force producing cross-bridges in skeletal muscle fibers activated by a substoichiometric amount of ATP.
  Biophys J, 85, 1741-1753.  
  12750333 U.Nongthomba, M.Cummins, S.Clark, J.O.Vigoreaux, and J.C.Sparrow (2003).
Suppression of muscle hypercontraction by mutations in the myosin heavy chain gene of Drosophila melanogaster.
  Genetics, 164, 209-222.  
14580214 Y.M.Peyser, S.Shaya, K.Ajtai, T.P.Burghardt, and A.Muhlrad (2003).
Cosolvent-induced aggregation inhibits myosin ATPase activity by stabilizing the predominant transition intermediate.
  Biochemistry, 42, 12669-12675.  
12112135 A.E.Lew, A.R.Dluzewski, A.M.Johnson, and J.C.Pinder (2002).
Myosins of Babesia bovis: molecular characterisation, erythrocyte invasion, and phylogeny.
  Cell Motil Cytoskeleton, 52, 202-220.  
12454455 A.Mateja, Y.Devedjiev, D.Krowarsch, K.Longenecker, Z.Dauter, J.Otlewski, and Z.S.Derewenda (2002).
The impact of Glu-->Ala and Glu-->Asp mutations on the crystallization properties of RhoGDI: the structure of RhoGDI at 1.3 A resolution.
  Acta Crystallogr D Biol Crystallogr, 58, 1983-1991.
PDB code: 1kmt
12186978 A.Moretti, H.J.Weig, T.Ott, M.Seyfarth, H.P.Holthoff, D.Grewe, A.Gillitzer, L.Bott-Flügel, A.Schömig, M.Ungerer, and K.L.Laugwitz (2002).
Essential myosin light chain as a target for caspase-3 in failing myocardium.
  Proc Natl Acad Sci U S A, 99, 11860-11865.  
12297624 D.M.Himmel, S.Gourinath, L.Reshetnikova, Y.Shen, A.G.Szent-Györgyi, and C.Cohen (2002).
Crystallographic findings on the internally uncoupled and near-rigor states of myosin: further insights into the mechanics of the motor.
  Proc Natl Acad Sci U S A, 99, 12645-12650.
PDB codes: 1kk7 1kk8 1kqm 1kwo 1l2o
11901423 D.M.Swank, A.F.Knowles, J.A.Suggs, F.Sarsoza, A.Lee, D.W.Maughan, and S.I.Bernstein (2002).
The myosin converter domain modulates muscle performance.
  Nat Cell Biol, 4, 312-316.  
12393751 G.Tsiavaliaris, S.Fujita-Becker, R.Batra, D.I.Levitsky, F.J.Kull, M.A.Geeves, and D.J.Manstein (2002).
Mutations in the relay loop region result in dominant-negative inhibition of myosin II function in Dictyostelium.
  EMBO Rep, 3, 1099-1105.  
12096063 H.Fujita, D.Sasaki, K.Fukuda, and S.Ishiwata (2002).
Myosin light chain 2 modulates MgADP-induced contraction in rabbit skeletal and bovine cardiac skinned muscle.
  J Physiol, 542, 221-229.  
12429851 H.Onishi, T.Ohki, N.Mochizuki, and M.F.Morales (2002).
Early stages of energy transduction by myosin: roles of Arg in switch I, of Glu in switch II, and of the salt-bridge between them.
  Proc Natl Acad Sci U S A, 99, 15339-15344.  
12023239 J.Borejdo, D.S.Ushakov, and I.Akopova (2002).
Regulatory and essential light chains of myosin rotate equally during contraction of skeletal muscle.
  Biophys J, 82, 3150-3159.  
11916869 J.E.Baker, C.Brosseau, P.B.Joel, and D.M.Warshaw (2002).
The biochemical kinetics underlying actin movement generated by one and many skeletal muscle myosin molecules.
  Biophys J, 82, 2134-2147.  
11916868 J.Gu, S.Xu, and L.C.Yu (2002).
A model of cross-bridge attachment to actin in the A*M*ATP state based on x-ray diffraction from permeabilized rabbit psoas muscle.
  Biophys J, 82, 2123-2133.  
12080126 J.S.Davis, C.L.Satorius, and N.D.Epstein (2002).
Kinetic effects of myosin regulatory light chain phosphorylation on skeletal muscle contraction.
  Biophys J, 83, 359-370.  
12124286 M.G.Bell, R.E.Dale, U.A.van der Heide, and Y.E.Goldman (2002).
Polarized fluorescence depletion reports orientation distribution and rotational dynamics of muscle cross-bridges.
  Biophys J, 83, 1050-1073.  
12080136 M.J.Lang, C.L.Asbury, J.W.Shaevitz, and S.M.Block (2002).
An automated two-dimensional optical force clamp for single molecule studies.
  Biophys J, 83, 491-501.  
11810692 M.J.Tyska, and D.M.Warshaw (2002).
The myosin power stroke.
  Cell Motil Cytoskeleton, 51, 1.  
12032065 M.Kollmar, U.Dürrwang, W.Kliche, D.J.Manstein, and F.J.Kull (2002).
Crystal structure of the motor domain of a class-I myosin.
  EMBO J, 21, 2517-2525.
PDB code: 1lkx
12124288 N.A.Koubassova, and A.K.Tsaturyan (2002).
Direct modeling of x-ray diffraction pattern from skeletal muscle in rigor.
  Biophys J, 83, 1082-1097.  
12423368 O.P.Nikolaeva, V.N.Orlov, A.A.Bobkov, and D.I.Levitsky (2002).
Differential scanning calorimetric study of myosin subfragment 1 with tryptic cleavage at the N-terminal region of the heavy chain.
  Eur J Biochem, 269, 5678-5688.  
12453307 P.G.Gillespie, and J.L.Cyr (2002).
Calmodulin binding to recombinant myosin-1c and myosin-1c IQ peptides.
  BMC Biochem, 3, 31.  
11959993 P.J.Griffiths, M.A.Bagni, B.Colombini, H.Amenitsch, S.Bernstorff, C.C.Ashley, G.Cecchi, and H.Ameritsch (2002).
Changes in myosin S1 orientation and force induced by a temperature increase.
  Proc Natl Acad Sci U S A, 99, 5384-5389.  
11867464 R.W.Kensler (2002).
Mammalian cardiac muscle thick filaments: their periodicity and interactions with actin.
  Biophys J, 82, 1497-1508.  
12499355 S.Burgess, M.Walker, F.Wang, J.R.Sellers, H.D.White, P.J.Knight, and J.Trinick (2002).
The prepower stroke conformation of myosin V.
  J Cell Biol, 159, 983-991.  
11814335 S.Park, and T.P.Burghardt (2002).
Tyrosine mediated tryptophan ATP sensitivity in skeletal myosin.
  Biochemistry, 41, 1436-1444.  
11916867 S.Xu, J.Gu, G.Melvin, and L.C.Yu (2002).
Structural characterization of weakly attached cross-bridges in the A*M*ATP state in permeabilized rabbit psoas muscle.
  Biophys J, 82, 2111-2122.  
11972024 T.Chakrabarty, M.Xiao, R.Cooke, and P.R.Selvin (2002).
Holding two heads together: stability of the myosin II rod measured by resonance energy transfer between the heads.
  Proc Natl Acad Sci U S A, 99, 6011-6016.  
11964242 T.Kraft, T.Mattei, A.Radocaj, B.Piep, C.Nocula, M.Furch, and B.Brenner (2002).
Structural features of cross-bridges in isometrically contracting skeletal muscle.
  Biophys J, 82, 2536-2547.  
12220198 W.Bernt, K.Polosukhina, B.Weiner, W.Tscharnuter, and S.Highsmith (2002).
Active site control of myosin cross-bridge zeta potential.
  Biochemistry, 41, 11308-11314.  
11297926 A.Houdusse, and H.L.Sweeney (2001).
Myosin motors: missing structures and hidden springs.
  Curr Opin Struct Biol, 11, 182-194.  
11425314 B.A.Baumann, B.D.Hambly, K.Hideg, and P.G.Fajer (2001).
The regulatory domain of the myosin head behaves as a rigid lever.
  Biochemistry, 40, 7868-7873.  
11170442 D.D.Root, and K.Wang (2001).
High-affinity actin-binding nebulin fragments influence the actoS1 complex.
  Biochemistry, 40, 1171-1186.  
11935366 H.G.Westra, J.A.Berden, W.J.Pasman, I.Pool, and J.E.van Doorn (2001).
A model for regulation of the Mg(2+)-stimulated acto-myosin-ATPase activity: inhibition of the formation of actin-myosin complex and the Mg( 2+)-stimulated acto-myosin-ATPase activity by IMP and AMP.
  Arch Physiol Biochem, 109, 316-322.  
11222303 J.Juanhuix, J.Bordas, J.Campmany, A.Svensson, M.L.Bassford, and T.Narayanan (2001).
Axial disposition of myosin heads in isometrically contracting muscles.
  Biophys J, 80, 1429-1441.  
11443548 J.Schönberger, and C.E.Seidman (2001).
Many roads lead to a broken heart: the genetics of dilated cardiomyopathy.
  Am J Hum Genet, 69, 249-260.  
11169765 L.Liu, J.Zhou, and T.C.Pesacreta (2001).
Maize myosins: diversity, localization, and function.
  Cell Motil Cytoskeleton, 48, 130-148.  
11699641 M.M.Khan, and M.Komiyama (2001).
The second EF-hand is responsible for the isoform-specific sorting of myosin essential light chain.
  Cell Struct Funct, 26, 243-251.  
11387196 M.Yun, X.Zhang, C.G.Park, H.W.Park, and S.A.Endow (2001).
A structural pathway for activation of the kinesin motor ATPase.
  EMBO J, 20, 2611-2618.
PDB codes: 1f9t 1f9u 1f9v 1f9w
11606291 N.Okimoto, K.Yamanaka, J.Ueno, M.Hata, T.Hoshino, and M.Tsuda (2001).
Theoretical studies of the ATP hydrolysis mechanism of myosin.
  Biophys J, 81, 2786-2794.  
11093259 P.Romero, Z.Obradovic, X.Li, E.C.Garner, C.J.Brown, and A.K.Dunker (2001).
Sequence complexity of disordered protein.
  Proteins, 42, 38-48.  
11170382 S.Kojima, K.Konishi, K.Katoh, K.Fujiwara, H.M.Martinez, M.F.Morales, and H.Onishi (2001).
Functional roles of ionic and hydrophobic surface loops in smooth muscle myosin: their interactions with actin.
  Biochemistry, 40, 657-664.  
11468689 S.Melchionda, N.Ahituv, L.Bisceglia, T.Sobe, F.Glaser, R.Rabionet, M.L.Arbones, A.Notarangelo, E.Di Iorio, M.Carella, L.Zelante, X.Estivill, K.B.Avraham, and P.Gasparini (2001).
MYO6, the human homologue of the gene responsible for deafness in Snell's waltzer mice, is mutated in autosomal dominant nonsyndromic hearing loss.
  Am J Hum Genet, 69, 635-640.  
11163130 T.Hasson, and R.E.Cheney (2001).
Mechanisms of motor protein reversal.
  Curr Opin Cell Biol, 13, 29-35.  
11294650 T.P.Burghardt, A.R.Cruz-Walker, S.Park, and K.Ajtai (2001).
Conformation of myosin interdomain interactions during contraction: deductions from muscle fibers using polarized fluorescence.
  Biochemistry, 40, 4821-4833.  
11294651 T.P.Burghardt, S.Park, and K.Ajtai (2001).
Conformation of myosin interdomain interactions during contraction: deductions from proteins in solution.
  Biochemistry, 40, 4834-4843.  
11287639 T.Wendt, D.Taylor, K.M.Trybus, and K.Taylor (2001).
Three-dimensional image reconstruction of dephosphorylated smooth muscle heavy meromyosin reveals asymmetry in the interaction between myosin heads and placement of subfragment 2.
  Proc Natl Acad Sci U S A, 98, 4361-4366.
PDB code: 1i84
11226153 W.Kliche, S.Fujita-Becker, M.Kollmar, D.J.Manstein, and F.J.Kull (2001).
Structure of a genetically engineered molecular motor.
  EMBO J, 20, 40-46.
PDB code: 1g8x
11459943 X.Liu, N.Osherov, R.Yamashita, H.Brzeska, E.D.Korn, and G.S.May (2001).
Myosin I mutants with only 1% of wild-type actin-activated MgATPase activity retain essential in vivo function(s).
  Proc Natl Acad Sci U S A, 98, 9122-9127.  
11251058 Y.B.Sun, K.Hilber, and M.Irving (2001).
Effect of active shortening on the rate of ATP utilisation by rabbit psoas muscle fibres.
  J Physiol, 531, 781-791.  
11356282 Y.Ishii, A.Ishijima, and T.Yanagida (2001).
Single molecule nanomanipulation of biomolecules.
  Trends Biotechnol, 19, 211-216.  
10866971 A.A.Bobkov, and E.Reisler (2000).
Is SH1-SH2-cross-linked myosin subfragment 1 a structural analog of the weakly-bound state of myosin?
  Biophys J, 79, 460-467.  
11016966 A.Houdusse, A.G.Szent-Gyorgyi, and C.Cohen (2000).
Three conformational states of scallop myosin S1.
  Proc Natl Acad Sci U S A, 97, 11238-11243.
PDB codes: 1dfk 1dfl
11123942 A.Málnási-Csizmadia, R.J.Woolley, and C.R.Bagshaw (2000).
Resolution of conformational states of Dictyostelium myosin II motor domain using tryptophan (W501) mutants: implications for the open-closed transition identified by crystallography.
  Biochemistry, 39, 16135-16146.  
10962092 B.Pliszka, E.Karczewska, and B.Wawro (2000).
Nucleotide-induced movements in the myosin head near the converter region.
  Biochim Biophys Acta, 1481, 55-62.  
10998634 D.M.Swank, L.Wells, W.A.Kronert, G.E.Morrill, and S.I.Bernstein (2000).
Determining structure/function relationships for sarcomeric myosin heavy chain by genetic and transgenic manipulation of Drosophila.
  Microsc Res Tech, 50, 430-442.  
10998637 E.Bandman, and B.W.Rosser (2000).
Evolutionary significance of myosin heavy chain heterogeneity in birds.
  Microsc Res Tech, 50, 473-491.  
10891854 E.Frixione (2000).
Recurring views on the structure and function of the cytoskeleton: a 300-year epic.
  Cell Motil Cytoskeleton, 46, 73-94.  
11087368 E.M.De La Cruz, A.L.Wells, H.L.Sweeney, and E.M.Ostap (2000).
Actin and light chain isoform dependence of myosin V kinetics.
  Biochemistry, 39, 14196-14202.  
10618387 E.W.Becker (2000).
Kinetic equilibrium of forces and molecular events in muscle contraction.
  Proc Natl Acad Sci U S A, 97, 157-161.  
11093248 F.S.Espindola, D.M.Suter, L.B.Partata, T.Cao, J.S.Wolenski, R.E.Cheney, S.M.King, and M.S.Mooseker (2000).
The light chain composition of chicken brain myosin-Va: calmodulin, myosin-II essential light chains, and 8-kDa dynein light chain/PIN.
  Cell Motil Cytoskeleton, 47, 269-281.  
10820029 F.Wang, E.V.Harvey, M.A.Conti, D.Wei, and J.R.Sellers (2000).
A conserved negatively charged amino acid modulates function in human nonmuscle myosin IIA.
  Biochemistry, 39, 5555-5560.  
10998635 G.J.Lutz, and R.L.Lieber (2000).
Myosin isoforms in anuran skeletal muscle: their influence on contractile properties and in vivo muscle function.
  Microsc Res Tech, 50, 443-457.  
10836507 H.E.Huxley (2000).
Past, present and future experiments on muscle.
  Philos Trans R Soc Lond B Biol Sci, 355, 539-543.  
10827990 H.Iwamoto (2000).
Influence of ionic strength on the actomyosin reaction steps in contracting skeletal muscle fibers.
  Biophys J, 78, 3138-3149.  
10692329 J.J.MacLean, L.R.Chrin, and C.L.Berger (2000).
Dynamics at Lys-553 of the acto-myosin interface in the weakly and strongly bound states.
  Biophys J, 78, 1441-1448.  
10742591 J.M.Morel, and N.D'Hahan (2000).
The myosin motor: muscle contraction and in vitro movement.
  Biochim Biophys Acta, 1474, 128-132.  
10836495 K.C.Holmes, and M.A.Geeves (2000).
The structural basis of muscle contraction.
  Philos Trans R Soc Lond B Biol Sci, 355, 419-431.  
10677484 K.Konno, K.Ue, M.Khoroshev, H.Martinez, B.Ray, and M.F.Morales (2000).
Consequences of placing an intramolecular crosslink in myosin S1.
  Proc Natl Acad Sci U S A, 97, 1461-1466.  
10692332 K.Polosukhina, D.Eden, M.Chinn, and S.Highsmith (2000).
CaATP as a substrate to investigate the myosin lever arm hypothesis of force generation.
  Biophys J, 78, 1474-1481.  
10653805 M.K.Chinn, K.H.Myburgh, T.Pham, K.Franks-Skiba, and R.Cooke (2000).
The effect of polyethylene glycol on the mechanics and ATPase activity of active muscle fibers.
  Biophys J, 78, 927-939.  
10984097 M.Komiyama, M.M.Khan, N.Toyota, and Y.Shimada (2000).
Fast skeletal muscle isoforms exhibit the highest incorporation level into myofibrils and stress fibers among members of myosin alkali light chain isoform family.
  Cell Struct Funct, 25, 141-148.  
10880955 M.Nyitrai, G.Hild, E.Bódis, A.Lukács, and B.Somogyi (2000).
Flexibility of myosin-subfragment-1 in its complex with actin as revealed by fluorescence resonance energy transfer.
  Eur J Biochem, 267, 4334-4338.  
10684610 M.Tiepold, W.Kliche, J.Pfannstiel, and H.Faulstich (2000).
Stepwise modulation of ATPase activity, nucleotide trapping, and sliding motility of myosin S1 by modification of the thiol region with residues of increasing size.
  Biochemistry, 39, 1305-1315.  
10679363 N.Volkmann, and D.Hanein (2000).
Actomyosin: law and order in motility.
  Curr Opin Cell Biol, 12, 26-34.  
10706641 P.Mallick, K.E.Goodwill, S.Fitz-Gibbon, J.H.Miller, and D.Eisenberg (2000).
Selecting protein targets for structural genomics of Pyrobaculum aerophilum: validating automated fold assignment methods by using binary hypothesis testing.
  Proc Natl Acad Sci U S A, 97, 2450-2455.  
10836498 R.D.Vale, R.Case, E.Sablin, C.Hart, and R.Fletterick (2000).
Searching for kinesin's mechanical amplifier.
  Philos Trans R Soc Lond B Biol Sci, 355, 449-457.  
11376443 R.Roberts, and R.Brugada (2000).
Genetic aspects of arrhythmias.
  Am J Med Genet, 97, 310-318.  
10704233 S.C.Hopkins, R.D.Vale, and I.D.Kuntz (2000).
Inhibitors of kinesin activity from structure-based computer screening.
  Biochemistry, 39, 2805-2814.  
11015212 S.Highsmith, K.Polosukhina, and D.Eden (2000).
Myosin motor domain lever arm rotation is coupled to ATP hydrolysis.
  Biochemistry, 39, 12330-12335.  
10722875 S.L.Reck-Peterson, D.W.Provance, M.S.Mooseker, and J.A.Mercer (2000).
Class V myosins.
  Biochim Biophys Acta, 1496, 36-51.  
10995241 S.Park, and T.P.Burghardt (2000).
Isolating and localizing ATP-sensitive tryptophan emission in skeletal myosin subfragment 1.
  Biochemistry, 39, 11732-11741.  
  10880486 S.R.Halsell, B.I.Chu, and D.P.Kiehart (2000).
Genetic analysis demonstrates a direct link between rho signaling and nonmuscle myosin function during Drosophila morphogenesis.
  Genetics, 155, 1253-1265.  
11114175 T.Martinsson, A.Oldfors, N.Darin, K.Berg, H.Tajsharghi, M.Kyllerman, and J.Wahlstrom (2000).
Autosomal dominant myopathy: missense mutation (Glu-706 --> Lys) in the myosin heavy chain IIa gene.
  Proc Natl Acad Sci U S A, 97, 14614-14619.  
10920026 T.Nishizaka, R.Seo, H.Tadakuma, K.Kinosita, and S.Ishiwata (2000).
Characterization of single actomyosin rigor bonds: load dependence of lifetime and mechanical properties.
  Biophys J, 79, 962-974.  
10944206 T.Yanagida, and A.H.Iwane (2000).
A large step for myosin.
  Proc Natl Acad Sci U S A, 97, 9357-9359.  
10679365 T.Yanagida, K.Kitamura, H.Tanaka, A.Hikikoshi Iwane, and S.Esaki (2000).
Single molecule analysis of the actomyosin motor.
  Curr Opin Cell Biol, 12, 20-25.  
10836497 T.Yanagida, S.Esaki, A.H.Iwane, Y.Inoue, A.Ishijima, K.Kitamura, H.Tanaka, and M.Tokunaga (2000).
Single-motor mechanics and models of the myosin motor.
  Philos Trans R Soc Lond B Biol Sci, 355, 441-447.  
11007486 W.M.Shih, Z.Gryczynski, J.R.Lakowicz, and J.A.Spudich (2000).
A FRET-based sensor reveals large ATP hydrolysis-induced conformational changes and three distinct states of the molecular motor myosin.
  Cell, 102, 683-694.  
10694391 X.D.Li, J.Saito, R.Ikebe, K.Mabuchi, and M.Ikebe (2000).
The interaction between the regulatory light chain domains on two heads is critical for regulation of smooth muscle myosin.
  Biochemistry, 39, 2254-2260.  
10338210 A.Houdusse, V.N.Kalabokis, D.Himmel, A.G.Szent-Györgyi, and C.Cohen (1999).
Atomic structure of scallop myosin subfragment S1 complexed with MgADP: a novel conformation of the myosin head.
  Cell, 97, 459-470.
PDB code: 1b7t
10094549 A.R.Janecke, M.Meins, M.Sadeghi, K.Grundmann, E.Apfelstedt-Sylla, E.Zrenner, T.Rosenberg, and A.Gal (1999).
Twelve novel myosin VIIA mutations in 34 patients with Usher syndrome type I: confirmation of genetic heterogeneity.
  Hum Mutat, 13, 133-140.  
10545368 B.Brenner, T.Kraft, L.C.Yu, and J.M.Chalovich (1999).
Thin filament activation probed by fluorescence of N-((2-(Iodoacetoxy)ethyl)-N-methyl)amino-7-nitrobenz-2-oxa-1, 3-diazole-labeled troponin I incorporated into skinned fibers of rabbit psoas muscle
  Biophys J, 77, 2677-2691.  
10427096 C.A.Shelton, J.C.Carter, G.C.Ellis, and B.Bowerman (1999).
The nonmuscle myosin regulatory light chain gene mlc-4 is required for cytokinesis, anterior-posterior polarity, and body morphology during Caenorhabditis elegans embryogenesis.
  J Cell Biol, 146, 439-451.  
10545173 C.M.Yengo, L.Chrin, A.S.Rovner, and C.L.Berger (1999).
Intrinsic tryptophan fluorescence identifies specific conformational changes at the actomyosin interface upon actin binding and ADP release.
  Biochemistry, 38, 14515-14523.  
10090768 C.T.Murphy, and J.A.Spudich (1999).
The sequence of the myosin 50-20K loop affects Myosin's affinity for actin throughout the actin-myosin ATPase cycle and its maximum ATPase activity.
  Biochemistry, 38, 3785-3792.  
10423443 C.Xu, R.Craig, L.Tobacman, R.Horowitz, and W.Lehman (1999).
Tropomyosin positions in regulated thin filaments revealed by cryoelectron microscopy.
  Biophys J, 77, 985-992.  
9916031 E.A.Bobkova, A.A.Bobkov, D.I.Levitsky, and E.Reisler (1999).
Effects of SH1 and SH2 modifications on myosin: similarities and differences.
  Biophys J, 76, 1001-1007.  
10508775 G.Stubbs (1999).
Developments in fiber diffraction.
  Curr Opin Struct Biol, 9, 615-619.  
10494851 J.Müller, A.Marx, S.Sack, Y.H.Song, and E.Mandelkow (1999).
The structure of the nucleotide-binding site of kinesin.
  Biol Chem, 380, 981-992.  
10571184 K.A.Taylor, H.Schmitz, M.C.Reedy, Y.E.Goldman, C.Franzini-Armstrong, H.Sasaki, R.T.Tregear, K.Poole, C.Lucaveche, R.J.Edwards, L.F.Chen, H.Winkler, and M.K.Reedy (1999).
Tomographic 3D reconstruction of quick-frozen, Ca2+-activated contracting insect flight muscle.
  Cell, 99, 421-431.  
10350461 K.Ajtai, Y.M.Peyser, S.Park, T.P.Burghardt, and A.Muhlrad (1999).
Trinitrophenylated reactive lysine residue in myosin detects lever arm movement during the consecutive steps of ATP hydrolysis.
  Biochemistry, 38, 6428-6440.  
  10493582 K.Kirshenbaum, M.Young, and S.Highsmith (1999).
Predicting allosteric switches in myosins.
  Protein Sci, 8, 1806-1815.  
9890887 K.Nakashima, H.Ishida, S.Y.Ohki, K.Hikichi, and M.Yazawa (1999).
Calcium binding induces interaction between the N- and C-terminal domains of yeast calmodulin and modulates its overall conformation.
  Biochemistry, 38, 98.  
10872464 M.A.Geeves, and K.C.Holmes (1999).
Structural mechanism of muscle contraction.
  Annu Rev Biochem, 68, 687-728.  
10089339 M.Kobayashi, M.Kubota, and Y.Matsuura (1999).
Crystallization and improvement of crystal quality for x-ray diffraction of maltooligosyl trehalose synthase by reductive methylation of lysine residues.
  Acta Crystallogr D Biol Crystallogr, 55, 931-933.  
  10493576 M.Young, K.Kirshenbaum, K.A.Dill, and S.Highsmith (1999).
Predicting conformational switches in proteins.
  Protein Sci, 8, 1752-1764.  
17030326 N.Errington, O.Byron, and A.J.Rowe (1999).
Conformational spectra--probing protein conformational changes.
  Biophys Chem, 80, 189-197.  
10029542 O.A.Andreev, L.D.Saraswat, S.Lowey, C.Slaughter, and J.Borejdo (1999).
Interaction of the N-terminus of chicken skeletal essential light chain 1 with F-actin.
  Biochemistry, 38, 2480-2485.  
10563488 P.S.Andersen, O.Havndrup, H.Bundgaard, L.A.Larsen, J.Vuust, K.Kjeldsen, and M.Christiansen (1999).
Adult-onset familial hypertrophic cardiomyopathy caused by a novel mutation, R694C, in the MYH7 gene.
  Clin Genet, 56, 244-246.  
10531021 R.Cooke (1999).
Myosin structure: does the tail wag the dog?
  Curr Biol, 9, R773-R775.  
10611679 R.D.Vale (1999).
Millennial musings on molecular motors.
  Trends Cell Biol, 9, M38-M42.  
10202143 R.M.Cripps, J.A.Suggs, and S.I.Bernstein (1999).
Assembly of thick filaments and myofibrils occurs in the absence of the myosin head.
  EMBO J, 18, 1793-1804.  
10220335 R.T.McKay, B.P.Tripet, J.R.Pearlstone, L.B.Smillie, and B.D.Sykes (1999).
Defining the region of troponin-I that binds to troponin-C.
  Biochemistry, 38, 5478-5489.  
9927691 R.Vemuri, E.B.Lankford, K.Poetter, S.Hassanzadeh, K.Takeda, Z.X.Yu, V.J.Ferrans, and N.D.Epstein (1999).
The stretch-activation response may be critical to the proper functioning of the mammalian heart.
  Proc Natl Acad Sci U S A, 96, 1048-1053.  
10066911 S.Fujita, T.Nawata, and K.Yamada (1999).
Fluorescence changes of a label attached near the myosin active site on nucleotide binding in rat skeletal muscle fibres.
  J Physiol, 515, 869-880.  
10413484 S.Ramachandran, and D.D.Thomas (1999).
Rotational dynamics of the regulatory light chain in scallop muscle detected by time-resolved phosphorescence anisotropy.
  Biochemistry, 38, 9097-9104.  
10231357 S.Sack, F.J.Kull, and E.Mandelkow (1999).
Motor proteins of the kinesin family. Structures, variations, and nucleotide binding sites.
  Eur J Biochem, 262, 1.  
10704189 T.B.Friedman, J.R.Sellers, and K.B.Avraham (1999).
Unconventional myosins and the genetics of hearing loss.
  Am J Med Genet, 89, 147-157.  
10613897 T.Wendt, D.Taylor, T.Messier, K.M.Trybus, and K.A.Taylor (1999).
Visualization of head-head interactions in the inhibited state of smooth muscle myosin.
  J Cell Biol, 147, 1385-1390.  
10085296 W.A.Kronert, A.Acebes, A.Ferrús, and S.I.Bernstein (1999).
Specific myosin heavy chain mutations suppress troponin I defects in Drosophila muscles.
  J Cell Biol, 144, 989.  
10406961 Y.M.Peyser, and A.Muhlrad (1999).
Actin and nucleotide induced conformational changes in the vicinity of Lys553 in myosin subfragment 1.
  Eur J Biochem, 263, 511-517.  
9484957 A.B.Metcalf (1998).
Immunolocalization of myosin Ibeta in the hair cell's hair bundle.
  Cell Motil Cytoskeleton, 39, 159-165.  
9458041 A.Ishijima, H.Kojima, T.Funatsu, M.Tokunaga, H.Higuchi, H.Tanaka, and T.Yanagida (1998).
Simultaneous observation of individual ATPase and mechanical events by a single myosin molecule during interaction with actin.
  Cell, 92, 161-171.  
9657680 A.L.Friedman, M.A.Geeves, D.J.Manstein, and J.A.Spudich (1998).
Kinetic characterization of myosin head fragments with long-lived myosin.ATP states.
  Biochemistry, 37, 9679-9687.  
9887959 A.M.Lauzon, K.M.Trybus, and D.M.Warshaw (1998).
Molecular mechanics of two smooth muscle heavy meromyosin constructs that differ by an insert in the motor domain.
  Acta Physiol Scand, 164, 357-361.  
  9799259 A.M.Rushforth, C.C.White, and P.Anderson (1998).
Functions of the Caenorhabditis elegans regulatory myosin light chain genes mlc-1 and mlc-2.
  Genetics, 150, 1067-1077.  
9763625 A.S.Khromov, A.V.Somlyo, and A.P.Somlyo (1998).
Thiophosphorylation of myosin light chain increases rigor stiffness of rabbit smooth muscle.
  J Physiol, 512, 345-350.  
9860947 B.O.Carragher, N.Cheng, Z.Y.Wang, E.D.Korn, A.Reilein, D.M.Belnap, J.A.Hammer, and A.C.Steven (1998).
Structural invariance of constitutively active and inactive mutants of acanthamoeba myosin IC bound to F-actin in the rigor and ADP-bound states.
  Proc Natl Acad Sci U S A, 95, 15206-15211.  
  9691038 B.Patterson (1998).
Intragenic suppressors of Dictyostelium myosin G680 mutants demarcate discrete structural elements. Implications for conformational states of the motor.
  Genetics, 149, 1799-1807.  
9707415 C.Davies, R.B.Gerstner, D.E.Draper, V.Ramakrishnan, and S.W.White (1998).
The crystal structure of ribosomal protein S4 reveals a two-domain molecule with an extensive RNA-binding surface: one domain shows structural homology to the ETS DNA-binding motif.
  EMBO J, 17, 4545-4558.  
9789020 C.M.Yengo, P.M.Fagnant, L.Chrin, A.S.Rovner, and C.L.Berger (1998).
Smooth muscle myosin mutants containing a single tryptophan reveal molecular interactions at the actin-binding interface.
  Proc Natl Acad Sci U S A, 95, 12944-12949.  
9635762 C.Sabido-David, B.Brandmeier, J.S.Craik, J.E.Corrie, D.R.Trentham, and M.Irving (1998).
Steady-state fluorescence polarization studies of the orientation of myosin regulatory light chains in single skeletal muscle fibers using pure isomers of iodoacetamidotetramethylrhodamine.
  Biophys J, 74, 3083-3092.  
9578557 C.T.Murphy, and J.A.Spudich (1998).
Dictyostelium myosin 25-50K loop substitutions specifically affect ADP release rates.
  Biochemistry, 37, 6738-6744.  
9653135 D.M.Warshaw, E.Hayes, D.Gaffney, A.M.Lauzon, J.Wu, G.Kennedy, K.Trybus, S.Lowey, and C.Berger (1998).
Myosin conformational states determined by single fluorophore polarization.
  Proc Natl Acad Sci U S A, 95, 8034-8039.  
9826617 E.B.Getz, R.Cooke, and S.L.Lehman (1998).
Phase transition in force during ramp stretches of skeletal muscle.
  Biophys J, 75, 2971-2983.  
9591671 E.Burmeister Getz, R.Cooke, and P.R.Selvin (1998).
Luminescence resonance energy transfer measurements in myosin.
  Biophys J, 74, 2451-2458.  
9449337 E.Pate, K.Franks-Skiba, and R.Cooke (1998).
Depletion of phosphate in active muscle fibers probes actomyosin states within the powerstroke.
  Biophys J, 74, 369-380.  
9852149 F.Buss, J.Kendrick-Jones, C.Lionne, A.E.Knight, G.P.Côté, and J.Paul Luzio (1998).
The localization of myosin VI at the golgi complex and leading edge of fibroblasts and its phosphorylation and recruitment into membrane ruffles of A431 cells after growth factor stimulation.
  J Cell Biol, 143, 1535-1545.  
9521782 F.J.van de Loo, and M.E.Salvucci (1998).
Involvement of two aspartate residues of Rubisco activase in coordination of the ATP gamma-phosphate and subunit cooperativity.
  Biochemistry, 37, 4621-4625.  
9501981 F.Kozielski, I.Arnal, and R.H.Wade (1998).
A model of the microtubule-kinesin complex based on electron cryomicroscopy and X-ray crystallography.
  Curr Biol, 8, 191-198.  
9787775 G.Goldspink (1998).
Selective gene expression during adaptation of muscle in response to different physiological demands.
  Comp Biochem Physiol B Biochem Mol Biol, 120, 5.  
9601027 G.Wu, A.Wong, F.Qian, and R.C.Lu (1998).
Phosphorylation changes the spatial relationship between Glu124-Arg143 and Cys18 and Cys165 of the regulatory light chain in smooth muscle myosin.
  Biochemistry, 37, 7676-7685.  
9538695 H.E.Huxley (1998).
Getting to grips with contraction: the interplay of structure and biochemistry.
  Trends Biochem Sci, 23, 84-87.  
9512041 H.Iwamoto (1998).
Thin filament cooperativity as a major determinant of shortening velocity in skeletal muscle fibers.
  Biophys J, 74, 1452-1464.  
9618467 H.Onishi, S.Kojima, K.Katoh, K.Fujiwara, H.M.Martinez, and M.F.Morales (1998).
Functional transitions in myosin: formation of a critical salt-bridge and transmission of effect to the sensitive tryptophan.
  Proc Natl Acad Sci U S A, 95, 6653-6658.  
  9594535 H.P.Vosberg (1998).
[Genetic causes of hypertrophic cardiomyopathy]
  Med Klin (Munich), 93, 252-259.  
9746529 H.Tanaka, A.Ishijima, M.Honda, K.Saito, and T.Yanagida (1998).
Orientation dependence of displacements by a single one-headed myosin relative to the actin filament.
  Biophys J, 75, 1886-1894.  
  9560408 J.D.Huang, M.J.Cope, V.Mermall, M.C.Strobel, J.Kendrick-Jones, L.B.Russell, M.S.Mooseker, N.G.Copeland, and N.A.Jenkins (1998).
Molecular genetic dissection of mouse unconventional myosin-VA: head region mutations.
  Genetics, 148, 1951-1961.  
9531555 J.D.Jontes, E.M.Ostap, T.D.Pollard, and R.A.Milligan (1998).
Three-dimensional structure of Acanthamoeba castellanii myosin-IB (MIB) determined by cryoelectron microscopy of decorated actin filaments.
  J Cell Biol, 141, 155-162.  
9811855 J.H.Zang, and J.A.Spudich (1998).
Myosin II localization during cytokinesis occurs by a mechanism that does not require its motor domain.
  Proc Natl Acad Sci U S A, 95, 13652-13657.  
9449336 J.R.Patel, G.M.Diffee, X.P.Huang, and R.L.Moss (1998).
Phosphorylation of myosin regulatory light chain eliminates force-dependent changes in relaxation rates in skeletal muscle.
  Biophys J, 74, 360-368.  
9808035 K.C.Holmes (1998).
Picture story. A powerful stroke.
  Nat Struct Biol, 5, 940-942.  
9853018 K.Jostarndt-Fögen, A.Puntschart, H.Hoppeler, and R.Billeter (1998).
Fibre-type specific expression of fast and slow essential myosin light chain mRNAs in trained human skeletal muscles.
  Acta Physiol Scand, 164, 299-308.  
9533706 L.Eligula, L.Chuang, M.L.Phillips, M.Motoki, K.Seguro, and A.Muhlrad (1998).
Transglutaminase-induced cross-linking between subdomain 2 of G-actin and the 636-642 lysine-rich loop of myosin subfragment 1.
  Biophys J, 74, 953-963.  
9843439 L.K.Nitao, and E.Reisler (1998).
Probing the conformational states of the SH1-SH2 helix in myosin: a cross-linking approach.
  Biochemistry, 37, 16704-16710.  
9609698 L.Xie, and M.Schoenberg (1998).
Binding of SH1-SH2-modified myosin subfragment-1 to actin.
  Biochemistry, 37, 8048-8053.  
9572846 M.Furch, M.A.Geeves, and D.J.Manstein (1998).
Modulation of actin affinity and actomyosin adenosine triphosphatase by charge changes in the myosin motor domain.
  Biochemistry, 37, 6317-6326.  
9722650 M.Gerstein, and W.Krebs (1998).
A database of macromolecular motions.
  Nucleic Acids Res, 26, 4280-4290.  
9748336 M.Ikebe, M.Yamada, K.Mabuchi, T.Kambara, and R.Ikebe (1998).
A specific amino acid sequence at the head-rod junction is not critical for the phosphorylation-dependent regulation of smooth muscle myosin.
  Biochemistry, 37, 13285-13290.  
9860965 M.Xiao, H.Li, G.E.Snyder, R.Cooke, R.G.Yount, and P.R.Selvin (1998).
Conformational changes between the active-site and regulatory light chain of myosin as determined by luminescence resonance energy transfer: the effect of nucleotides and actin.
  Proc Natl Acad Sci U S A, 95, 15309-15314.  
9922150 O.A.Andreev, D.S.Ushakov, and J.Borejdo (1998).
Effect of ADP on binding of skeletal S1 to F-actin.
  Biochemistry, 37, 17836-17842.  
9772169 O.Roopnarine, A.G.Szent-Györgyi, and D.D.Thomas (1998).
Microsecond rotational dynamics of spin-labeled myosin regulatory light chain induced by relaxation and contraction of scallop muscle.
  Biochemistry, 37, 14428-14436.  
9700160 R.C.Stevens, and T.N.Davis (1998).
Mlc1p is a light chain for the unconventional myosin Myo2p in Saccharomyces cerevisiae.
  J Cell Biol, 142, 711-722.  
9501153 R.Cooke (1998).
New angle on myosin.
  Proc Natl Acad Sci U S A, 95, 2720-2722.  
9741621 R.Dominguez, Y.Freyzon, K.M.Trybus, and C.Cohen (1998).
Crystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: visualization of the pre-power stroke state.
  Cell, 94, 559-571.
PDB codes: 1br1 1br2 1br4
9585577 R.R.Biekofsky, S.R.Martin, J.P.Browne, P.M.Bayley, and J.Feeney (1998).
Ca2+ coordination to backbone carbonyl oxygen atoms in calmodulin and other EF-hand proteins: 15N chemical shifts as probes for monitoring individual-site Ca2+ coordination.
  Biochemistry, 37, 7617-7629.  
9730814 R.T.McKay, J.R.Pearlstone, D.C.Corson, S.M.Gagné, L.B.Smillie, and B.D.Sykes (1998).
Structure and interaction site of the regulatory domain of troponin-C when complexed with the 96-148 region of troponin-I.
  Biochemistry, 37, 12419-12430.
PDB code: 1blq
9635763 S.C.Hopkins, C.Sabido-David, J.E.Corrie, M.Irving, and Y.E.Goldman (1998).
Fluorescence polarization transients from rhodamine isomers on the myosin regulatory light chain in skeletal muscle fibers.
  Biophys J, 74, 3093-3110.  
9472039 S.H.Lillie, and S.S.Brown (1998).
Smy1p, a kinesin-related protein that does not require microtubules.
  J Cell Biol, 140, 873-883.  
9512042 S.Highsmith, K.Duignan, K.Franks-Skiba, K.Polosukhina, and R.Cooke (1998).
Reversible inactivation of myosin subfragment 1 activity by mechanical immobilization.
  Biophys J, 74, 1465-1472.  
9512013 S.Xu, L.C.Yu, and M.Schoenberg (1998).
Behavior of N-phenylmaleimide-reacted muscle fibers in magnesium-free rigor solution.
  Biophys J, 74, 1110-1114.  
9585528 T.Hiratsuka (1998).
Prodan fluorescence reflects differences in nucleotide-induced conformational states in the myosin head and allows continuous visualization of the ATPase reactions.
  Biochemistry, 37, 7167-7176.  
9609697 T.P.Burghardt, S.P.Garamszegi, S.Park, and K.Ajtai (1998).
Tertiary structural changes in the cleft containing the ATP sensitive tryptophan and reactive thiol are consistent with pivoting of the myosin heavy chain at Gly699.
  Biochemistry, 37, 8035-8047.  
9675167 W.Wriggers, and K.Schulten (1998).
Nucleotide-dependent movements of the kinesin motor domain predicted by simulated annealing.
  Biophys J, 75, 646-661.  
9618466 X.Sun, A.L.Bognar, E.N.Baker, and C.A.Smith (1998).
Structural homologies with ATP- and folate-binding enzymes in the crystal structure of folylpolyglutamate synthetase.
  Proc Natl Acad Sci U S A, 95, 6647-6652.
PDB code: 1fgs
9428702 A.Bartegi, C.Roustan, A.Chavanieu, R.Kassab, and A.Fattoum (1997).
Interaction of F-actin with synthetic peptides spanning the loop region of human cardiac beta-myosin heavy chain containing Arg403.
  Eur J Biochem, 250, 484-491.  
9223289 A.D.Mehta, J.T.Finer, and J.A.Spudich (1997).
Detection of single-molecule interactions using correlated thermal diffusion.
  Proc Natl Acad Sci U S A, 94, 7927-7931.  
9305951 A.M.Gulick, C.B.Bauer, J.B.Thoden, and I.Rayment (1997).
X-ray structures of the MgADP, MgATPgammaS, and MgAMPPNP complexes of the Dictyostelium discoideum myosin motor domain.
  Biochemistry, 36, 11619-11628.
PDB codes: 1mma 1mmg 1mmn
9230689 A.M.Gulick, and I.Rayment (1997).
Structural studies on myosin II: communication between distant protein domains.
  Bioessays, 19, 561-569.  
9275176 B.Adhikari, K.Hideg, and P.G.Fajer (1997).
Independent mobility of catalytic and regulatory domains of myosin heads.
  Proc Natl Acad Sci U S A, 94, 9643-9647.  
9057826 B.C.Phan, Y.M.Peyser, E.Reisler, and A.Muhlrad (1997).
Effect of complexes of ADP and phosphate analogs on the conformation of the Cys707-Cys697 region of myosin subfragment 1.
  Eur J Biochem, 243, 636-642.  
  9263923 C.Reggiani, E.J.Potma, R.Bottinelli, M.Canepari, M.A.Pellegrino, and G.J.Stienen (1997).
Chemo-mechanical energy transduction in relation to myosin isoform composition in skeletal muscle fibres of the rat.
  J Physiol, 502, 449-460.  
9341208 C.Smyczynski, and A.A.Kasprzak (1997).
Effect of nucleotides and actin on the orientation of the light chain-binding domain in myosin subfragment 1.
  Biochemistry, 36, 13201-13207.  
9251811 D.Eden, and S.Highsmith (1997).
Light chain-dependent myosin structural dynamics in solution investigated by transient electrical birefringence.
  Biophys J, 73, 952-958.  
9171833 D.Weil, P.Küssel, S.Blanchard, G.Lévy, F.Levi-Acobas, M.Drira, H.Ayadi, and C.Petit (1997).
The autosomal recessive isolated deafness, DFNB2, and the Usher 1B syndrome are allelic defects of the myosin-VIIA gene.
  Nat Genet, 16, 191-193.  
9083682 E.Homsher, J.Lacktis, and M.Regnier (1997).
Strain-dependent modulation of phosphate transients in rabbit skeletal muscle fibers.
  Biophys J, 72, 1780-1791.  
9315852 E.Pate, N.Naber, M.Matuska, K.Franks-Skiba, and R.Cooke (1997).
Opening of the myosin nucleotide triphosphate binding domain during the ATPase cycle.
  Biochemistry, 36, 12155-12166.  
9428521 F.Kozielski, S.Sack, A.Marx, M.Thormählen, E.Schönbrunn, V.Biou, A.Thompson, E.M.Mandelkow, and E.Mandelkow (1997).
The crystal structure of dimeric kinesin and implications for microtubule-dependent motility.
  Cell, 91, 985-994.
PDB code: 3kin
9244295 G.Woehlke, A.K.Ruby, C.L.Hart, B.Ly, N.Hom-Booher, and R.D.Vale (1997).
Microtubule interaction site of the kinesin motor.
  Cell, 90, 207-216.  
9092805 H.Onishi, M.F.Morales, S.Kojima, K.Katoh, and K.Fujiwara (1997).
Functional transitions in myosin: role of highly conserved Gly and Glu residues in the active site.
  Biochemistry, 36, 3767-3772.  
9348286 H.Schmitz, M.C.Reedy, M.K.Reedy, R.T.Tregear, and K.A.Taylor (1997).
Tomographic three-dimensional reconstruction of insect flight muscle partially relaxed by AMPPNP and ethylene glycol.
  J Cell Biol, 139, 695-707.  
9159126 I.Sase, H.Miyata, S.Ishiwata, and K.Kinosita (1997).
Axial rotation of sliding actin filaments revealed by single-fluorophore imaging.
  Proc Natl Acad Sci U S A, 94, 5646-5650.  
9348285 J.D.Jontes, and R.A.Milligan (1997).
Brush border myosin-I structure and ADP-dependent conformational changes revealed by cryoelectron microscopy and image analysis.
  J Cell Biol, 139, 683-693.  
9405612 J.D.Jontes, R.A.Milligan, T.D.Pollard, and E.M.Ostap (1997).
Kinetic characterization of brush border myosin-I ATPase.
  Proc Natl Acad Sci U S A, 94, 14332-14337.  
9094325 J.M.Squire (1997).
Architecture and function in the muscle sarcomere.
  Curr Opin Struct Biol, 7, 247-257.  
9214290 K.C.Giese, and J.A.Spudich (1997).
Phenotypically selected mutations in myosin's actin binding domain demonstrate intermolecular contacts important for motor function.
  Biochemistry, 36, 8465-8473.  
9105042 K.D.Becker, K.R.Gottshall, R.Hickey, J.C.Perriard, and K.R.Chien (1997).
Point mutations in human beta cardiac myosin heavy chain have differential effects on sarcomeric structure and assembly: an ATP binding site change disrupts both thick and thin filaments, whereas hypertrophic cardiomyopathy mutations display normal assembly.
  J Cell Biol, 137, 131-140.  
9305989 K.Polosukhina, and S.Highsmith (1997).
Kinetic investigation of the ligand dependence of rabbit skeletal muscle myosin subfragment 1 Cys-697 and Cys-707 reactivities.
  Biochemistry, 36, 11952-11958.  
8990166 M.Sata, W.F.Stafford, K.Mabuchi, and M.Ikebe (1997).
The motor domain and the regulatory domain of myosin solely dictate enzymatic activity and phosphorylation-dependent regulation, respectively.
  Proc Natl Acad Sci U S A, 94, 91-96.  
8994589 M.Suzuki, J.Shigematsu, Y.Fukunishi, Y.Harada, T.Yanagida, and T.Kodama (1997).
Coupling of protein surface hydrophobicity change to ATP hydrolysis by myosin motor domain.
  Biophys J, 72, 18-23.  
9245400 N.Naber, R.Cooke, and E.Pate (1997).
Binding of ncd to microtubules induces a conformational change near the junction of the motor domain with the neck.
  Biochemistry, 36, 9681-9689.  
9200683 P.D.Moens, and C.G.dos Remedios (1997).
A conformational change in F-actin when myosin binds: fluorescence resonance energy transfer detects an increase in the radial coordinate of Cys-374.
  Biochemistry, 36, 7353-7360.  
9238011 R.Mendelson, and E.P.Morris (1997).
The structure of the acto-myosin subfragment 1 complex: results of searches using data from electron microscopy and x-ray crystallography.
  Proc Natl Acad Sci U S A, 94, 8533-8538.
PDB code: 1alm
9348284 S.A.Burgess, M.L.Walker, H.D.White, and J.Trinick (1997).
Flexibility within myosin heads revealed by negative stain and single-particle analysis.
  J Cell Biol, 139, 675-681.  
9047298 S.Highsmith (1997).
Myosin regulatory light chain and nucleotide modulation of actin binding site electric charge.
  Biochemistry, 36, 2010-2016.  
9251806 S.Ishiwata, M.Miki, I.Shin, T.Funatsu, K.Yasuda, and C.G.dos Remedios (1997).
Interhead distances in myosin attached to F-actin estimated by fluorescence energy transfer spectroscopy.
  Biophys J, 73, 895-904.  
9370427 S.Malinchik, S.Xu, and L.C.Yu (1997).
Temperature-induced structural changes in the myosin thick filament of skinned rabbit psoas muscle.
  Biophys J, 73, 2304-2312.  
9116016 S.Park, K.Ajtai, and T.P.Burghardt (1997).
Mechanism for coupling free energy in ATPase to the myosin active site.
  Biochemistry, 36, 3368-3372.  
9370426 S.Xu, S.Malinchik, D.Gilroy, T.Kraft, B.Brenner, and L.C.Yu (1997).
X-ray diffraction studies of cross-bridges weakly bound to actin in relaxed skinned fibers of rabbit psoas muscle.
  Biophys J, 73, 2292-2303.  
9186010 T.Hasson, J.Walsh, J.Cable, M.S.Mooseker, S.D.Brown, and K.P.Steel (1997).
Effects of shaker-1 mutations on myosin-VIIa protein and mRNA expression.
  Cell Motil Cytoskeleton, 37, 127-138.  
9182663 T.Hasson, P.G.Gillespie, J.A.Garcia, R.B.MacDonald, Y.Zhao, A.G.Yee, M.S.Mooseker, and D.P.Corey (1997).
Unconventional myosins in inner-ear sensory epithelia.
  J Cell Biol, 137, 1287-1307.  
  9382088 T.Hasson (1997).
Unconventional myosins, the basis for deafness in mouse and man.
  Am J Hum Genet, 61, 801-805.  
9275174 T.P.Burghardt, S.P.Garamszegi, and K.Ajtai (1997).
Probes bound to myosin Cys-707 rotate during length transients in contraction.
  Proc Natl Acad Sci U S A, 94, 9631-9636.  
9369475 T.Shimada, N.Sasaki, R.Ohkura, and K.Sutoh (1997).
Alanine scanning mutagenesis of the switch I region in the ATPase site of Dictyostelium discoideum myosin II.
  Biochemistry, 36, 14037-14043.  
9138552 W.H.Guilford, D.E.Dupuis, G.Kennedy, J.Wu, J.B.Patlak, and D.M.Warshaw (1997).
Smooth muscle and skeletal muscle myosins produce similar unitary forces and displacements in the laser trap.
  Biophys J, 72, 1006-1021.  
9171832 X.Z.Liu, J.Walsh, P.Mburu, J.Kendrick-Jones, M.J.Cope, K.P.Steel, and S.D.Brown (1997).
Mutations in the myosin VIIA gene cause non-syndromic recessive deafness.
  Nat Genet, 16, 188-190.  
9083688 Y.C.Sasaki, K.Yasuda, Y.Suzuki, T.Ishibashi, I.Satoh, Y.Fujiki, and S.Ishiwata (1997).
Two-dimensional arrangement of a functional protein by cysteine-gold interaction: enzyme activity and characterization of a protein monolayer on a gold substrate.
  Biophys J, 72, 1842-1848.  
9208928 Y.Hirayama, and S.Watabe (1997).
Structural differences in the crossbridge head of temperature-associated myosin subfragment-1 isoforms from carp fast skeletal muscle.
  Eur J Biochem, 246, 380-387.  
9138576 Y.Zhang, Z.Shao, A.P.Somlyo, and A.V.Somlyo (1997).
Cryo-atomic force microscopy of smooth muscle myosin.
  Biophys J, 72, 1308-1318.  
8637864 A.A.Bobkov, E.A.Bobkova, S.H.Lin, and E.Reisler (1996).
The role of surface loops (residues 204-216 and 627-646) in the motor function of the myosin head.
  Proc Natl Acad Sci U S A, 93, 2285-2289.  
8928223 A.F.Wright, and I.Jackson (1996).
Myosin diversity and disease.
  Trends Genet, 12, 206-209.  
8672723 A.G.Szent-Györgyi (1996).
Regulation of contraction by calcium binding myosins.
  Biophys Chem, 59, 357-363.  
8805510 A.Houdusse, and C.Cohen (1996).
Structure of the regulatory domain of scallop myosin at 2 A resolution: implications for regulation.
  Structure, 4, 21-32.
PDB code: 1wdc
8994973 A.Houdusse, M.Silver, and C.Cohen (1996).
A model of Ca(2+)-free calmodulin binding to unconventional myosins reveals how calmodulin acts as a regulatory switch.
  Structure, 4, 1475-1490.
PDB code: 1aji
8799143 A.Weisberg, and S.Winegrad (1996).
Alteration of myosin cross bridges by phosphorylation of myosin-binding protein C in cardiac muscle.
  Proc Natl Acad Sci U S A, 93, 8999-9003.  
8785347 B.B.Adhikari, and P.G.Fajer (1996).
Myosin head orientation and mobility during isometric contraction: effects of osmotic compression.
  Biophys J, 70, 1872-1880.  
8913612 B.Brenner, S.Xu, J.M.Chalovich, and L.C.Yu (1996).
Radial equilibrium lengths of actomyosin cross-bridges in muscle.
  Biophys J, 71, 2751-2758.  
  8725228 B.Patterson, and J.A.Spudich (1996).
Cold-sensitive mutations of Dictyostelium myosin heavy chain highlight functional domains of the myosin motor.
  Genetics, 143, 801-810.  
8707847 C.A.Kelley, J.R.Sellers, D.L.Gard, D.Bui, R.S.Adelstein, and I.C.Baines (1996).
Xenopus nonmuscle myosin heavy chain isoforms have different subcellular localizations and enzymatic activities.
  J Cell Biol, 134, 675-687.  
8611530 C.A.Smith, and I.Rayment (1996).
X-ray structure of the magnesium(II).ADP.vanadate complex of the Dictyostelium discoideum myosin motor domain to 1.9 A resolution.
  Biochemistry, 35, 5404-5417.
PDB code: 1vom
8785318 C.A.Smith, and I.Rayment (1996).
Active site comparisons highlight structural similarities between myosin and other P-loop proteins.
  Biophys J, 70, 1590-1602.  
8816286 C.Aguado-Velasco, M.Véron, J.A.Rambow, and E.R.Kuczmarski (1996).
NDP kinase can modulate contraction of Dictyostelium cytoskeletons.
  Cell Motil Cytoskeleton, 34, 194-205.  
8619986 C.J.Miller, T.C.Doyle, E.Bobkova, D.Botstein, and E.Reisler (1996).
Mutational analysis of the role of hydrophobic residues in the 338-348 helix on actin in actomyosin interactions.
  Biochemistry, 35, 3670-3676.  
8968602 C.L.Berger, J.S.Craik, D.R.Trentham, J.E.Corrie, and Y.E.Goldman (1996).
Fluorescence polarization of skeletal muscle fibers labeled with rhodamine isomers on the myosin heavy chain.
  Biophys J, 71, 3330-3343.  
8906622 C.L.Perreault-Micale, V.N.Kalabokis, L.Nyitray, and A.G.Szent-Györgyi (1996).
Sequence variations in the surface loop near the nucleotide binding site modulate the ATP turnover rates of molluscan myosins.
  J Muscle Res Cell Motil, 17, 543-553.  
8805521 C.W.Müller, G.J.Schlauderer, J.Reinstein, and G.E.Schulz (1996).
Adenylate kinase motions during catalysis: an energetic counterweight balancing substrate binding.
  Structure, 4, 147-156.
PDB code: 4ake
8807883 D.D.Hackney (1996).
Myosin and kinesin: mother and child reunited.
  Chem Biol, 3, 525-528.  
8555221 D.Gopal, and M.Burke (1996).
Myosin subfragment 1 hydrophobicity changes associated with different nucleotide-induced conformations.
  Biochemistry, 35, 506-512.  
8622919 D.Weil, G.Levy, I.Sahly, F.Levi-Acobas, S.Blanchard, A.El-Amraoui, F.Crozet, H.Philippe, M.Abitbol, and C.Petit (1996).
Human myosin VIIA responsible for the Usher 1B syndrome: a predicted membrane-associated motor protein expressed in developing sensory epithelia.
  Proc Natl Acad Sci U S A, 93, 3232-3237.  
8785300 E.Kim, C.J.Miller, M.Motoki, K.Seguro, A.Muhlrad, and E.Reisler (1996).
Myosin-induced changes in F-actin: fluorescence probing of subdomain 2 by dansyl ethylenediamine attached to Gln-41.
  Biophys J, 70, 1439-1446.  
8842197 F.G.Díaz Baños, J.Bordas, J.Lowy, and A.Svensson (1996).
Small segmental rearrangements in the myosin head can explain force generation in muscle.
  Biophys J, 71, 576-589.  
8769415 F.Kinose, S.X.Wang, U.S.Kidambi, C.L.Moncman, and D.A.Winkelmann (1996).
Glycine 699 is pivotal for the motor activity of skeletal muscle myosin.
  J Cell Biol, 134, 895-909.  
8994081 G.J.Rapp, and J.S.Davis (1996).
X-ray diffraction studies on thermally induced tension generation in rigor muscle.
  J Muscle Res Cell Motil, 17, 617-629.  
8804617 G.M.Diffee, J.R.Patel, F.C.Reinach, M.L.Greaser, and R.L.Moss (1996).
Altered kinetics of contraction in skeletal muscle fibers containing a mutant myosin regulatory light chain with reduced divalent cation binding.
  Biophys J, 71, 341-350.  
8783394 H.Nakamura (1996).
Roles of electrostatic interaction in proteins.
  Q Rev Biophys, 29, 1.  
8736548 I.Rayment (1996).
Kinesin and myosin: molecular motors with similar engines.
  Structure, 4, 501-504.  
8952512 J.C.Grammer, J.A.Loo, C.G.Edmonds, C.R.Cremo, and R.G.Yount (1996).
Chemistry and mechanism of vanadate-promoted photooxidative cleavage of myosin.
  Biochemistry, 35, 15582-15592.  
8784354 J.Gollub, C.R.Cremo, and R.Cooke (1996).
ADP release produces a rotation of the neck region of smooth myosin but not skeletal myosin.
  Nat Struct Biol, 3, 796-802.  
9172757 J.R.Patel, G.M.Diffee, and R.L.Moss (1996).
Myosin regulatory light chain modulates the Ca2+ dependence of the kinetics of tension development in skeletal muscle fibers.
  Biophys J, 70, 2333-2340.  
8740428 J.R.Sellers, H.V.Goodson, and F.Wang (1996).
A myosin family reunion.
  J Muscle Res Cell Motil, 17, 7.  
8793719 J.R.Sellers (1996).
Kinesin and NCD, two structural cousins of myosin.
  J Muscle Res Cell Motil, 17, 173-175.  
8994878 K.C.Holmes (1996).
Muscle proteins--their actions and interactions.
  Curr Opin Struct Biol, 6, 781-789.  
8970737 K.M.Ruppel, and J.A.Spudich (1996).
Structure-function analysis of the motor domain of myosin.
  Annu Rev Cell Dev Biol, 12, 543-573.  
  8862525 K.M.Ruppel, and J.A.Spudich (1996).
Structure-function studies of the myosin motor domain: importance of the 50-kDa cleft.
  Mol Biol Cell, 7, 1123-1136.  
8673105 K.Poetter, H.Jiang, S.Hassanzadeh, S.R.Master, A.Chang, M.C.Dalakas, I.Rayment, J.R.Sellers, L.Fananapazir, and N.D.Epstein (1996).
Mutations in either the essential or regulatory light chains of myosin are associated with a rare myopathy in human heart and skeletal muscle.
  Nat Genet, 13, 63-69.  
8970724 K.R.Ayscough, and D.G.Drubin (1996).
ACTIN: general principles from studies in yeast.
  Annu Rev Cell Dev Biol, 12, 129-160.  
8756480 L.Zhao, J.Gollub, and R.Cooke (1996).
Orientation of paramagnetic probes attached to gizzard regulatory light chain bound to myosin heads in rabbit skeletal muscle.
  Biochemistry, 35, 10158-10165.  
  8947029 M.Anson, M.A.Geeves, S.E.Kurzawa, and D.J.Manstein (1996).
Myosin motors with artificial lever arms.
  EMBO J, 15, 6069-6074.  
8646534 M.B.Swindells, and M.Ikura (1996).
Pre-formation of the semi-open conformation by the apo-calmodulin C-terminal domain and implications binding IQ-motifs.
  Nat Struct Biol, 3, 501-504.  
8884597 M.D.Peterson, A.S.Urioste, and M.A.Titus (1996).
Dictyostelium discoideum myoJ: a member of a broadly defined myosin V class or a class XI unconventional myosin?
  J Muscle Res Cell Motil, 17, 411-424.  
  8900236 M.D.Weston, P.M.Kelley, L.D.Overbeck, M.Wagenaar, D.J.Orten, T.Hasson, Z.Y.Chen, D.Corey, M.Mooseker, J.Sumegi, C.Cremers, C.Moller, S.G.Jacobson, M.B.Gorin, and W.J.Kimberling (1996).
Myosin VIIA mutation screening in 189 Usher syndrome type 1 patients.
  Am J Hum Genet, 59, 1074-1083.  
8848832 M.Ikura (1996).
Calcium binding and conformational response in EF-hand proteins.
  Trends Biochem Sci, 21, 14-17.  
8805581 M.J.Cope, J.Whisstock, I.Rayment, and J.Kendrick-Jones (1996).
Conservation within the myosin motor domain: implications for structure and function.
  Structure, 4, 969-987.  
8804587 M.Kekic, W.Huang, P.D.Moens, B.D.Hambly, and C.G.dos Remedios (1996).
Distance measurements near the myosin head-rod junction using fluorescence spectroscopy.
  Biophys J, 71, 40-47.  
8692854 M.Mazumdar, A.Mikami, M.A.Gee, and R.B.Vallee (1996).
In vitro motility from recombinant dynein heavy chain.
  Proc Natl Acad Sci U S A, 93, 6552-6556.