PDBsum entry 2l3s

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protein links
Structural protein PDB id
Protein chain
163 a.a. *
* Residue conservation analysis
PDB id:
Name: Structural protein
Title: Structure of the autoinhibited crk
Structure: Autoinhibited crk protein. Chain: a. Synonym: proto-oncogenE C-crk, p38. Engineered: yes
Source: Gallus gallus. Bantam,chickens. Organism_taxid: 9031. Gene: crk. Expressed in: escherichia coli. Expression_system_taxid: 562.
NMR struc: 20 models
Authors: C.G.Kalodimos,P.Sarkar,T.Saleh,S.R.Tzeng,R.Birge
Key ref: P.Sarkar et al. (2011). Structural basis for regulation of the Crk signaling protein by a proline switch. Nat Chem Biol, 7, 51-57. PubMed id: 21131971
21-Sep-10     Release date:   08-Dec-10    
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Protein chain
Pfam   ArchSchema ?
Q04929  (CRK_CHICK) -  Adapter molecule crk
305 a.a.
163 a.a.
Key:    PfamA domain  Secondary structure  CATH domain


Nat Chem Biol 7:51-57 (2011)
PubMed id: 21131971  
Structural basis for regulation of the Crk signaling protein by a proline switch.
P.Sarkar, T.Saleh, S.R.Tzeng, R.B.Birge, C.G.Kalodimos.
No abstract given.


Literature references that cite this PDB file's key reference

  PubMed id Reference
21404360 C.G.Kalodimos (2011).
NMR reveals novel mechanisms of protein activity regulation.
  Protein Sci, 20, 773-782.  
21164511 L.K.Nicholson, and S.De (2011).
Structural biology: The twist in Crk signaling revealed.
  Nat Chem Biol, 7, 5-6.  
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time.