spacer
spacer

PDBsum entry 2ke0

Go to PDB code: 
protein links
Isomerase PDB id
2ke0
Jmol
Contents
Protein chain
117 a.a. *
* Residue conservation analysis
PDB id:
2ke0
Name: Isomerase
Title: Solution structure of peptidyl-prolyl cis-trans isomerase fr burkholderia pseudomallei
Structure: Peptidyl-prolyl cis-trans isomerase. Chain: a. Engineered: yes
Source: Burkholderia pseudomallei. Pseudomonas pseudomallei. Organism_taxid: 28450. Gene: fbp, bpss1823. Expressed in: escherichia coli. Expression_system_taxid: 562.
NMR struc: 20 models
Authors: S.Zheng,T.Leeper,A.Napuli,S.H.Nakazawa,G.Varani,Seattle Stru Genomics Center For Infectious Disease (Ssgcid)
Key ref: I.H.Norville et al. (2011). The structure of a Burkholderia pseudomallei immunophilin-inhibitor complex reveals new approaches to antimicrobial development. Biochem J, 437, 413-422. PubMed id: 21574961 DOI: 10.1042/BJ20110345
Date:
21-Jan-09     Release date:   03-Mar-09    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q63J95  (Q63J95_BURPS) -  Peptidyl-prolyl cis-trans isomerase
Seq:
Struc:
113 a.a.
117 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.5.2.1.8  - Peptidylprolyl isomerase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Peptidylproline (omega=180) = peptidylproline (omega=0)
Peptidylproline (omega=180)
= peptidylproline (omega=0)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     protein folding   2 terms 
  Biochemical function     isomerase activity     2 terms  

 

 
    Added reference    
 
 
DOI no: 10.1042/BJ20110345 Biochem J 437:413-422 (2011)
PubMed id: 21574961  
 
 
The structure of a Burkholderia pseudomallei immunophilin-inhibitor complex reveals new approaches to antimicrobial development.
I.H.Norville, K.O'Shea, M.Sarkar-Tyson, S.Zheng, R.W.Titball, G.Varani, N.J.Harmer.
 
  ABSTRACT  
 
No abstract given.