PDBsum entry 2k4a

Protein transport

PDB id: 2k4a

Contents

Protein chains

128 a.a. *

133 a.a. *

* Residue conservation analysis

PDB id:

2k4a

Name:

Protein transport

Title:

Fgf-1-c2a binary complex structure: a key component in the fibroblast growthfactor non-classical pathway

Structure:

Synaptotagmin-1. Chain: a. Fragment: c2 domain, unp residues 141-268. Synonym: synaptotagmin i, syti, p65, c2a. Engineered: yes. Heparin-binding growth factor 1. Chain: b. Fragment: unp residues 23-155. Synonym: hbgf-1, acidic fibroblast growth factor, afgf, beta-

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: syt1, svp65, syt. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: fgf1, fgfa.

NMR struc:

20 models

Authors:

C.Yu,S.K.Mohan

Key ref:

S.K.Mohan and c.yu Fgf-1-C2a binary complex structure: key component in the acidic fibroblast growth factor release. To be published, .

Date:

02-Jun-08 Release date: 09-Jun-09

Protein chain

P21579  (SYT1_HUMAN) -  Synaptotagmin-1 from Homo sapiens

Seq: 422 a.a.

Struc: 128 a.a.

Protein chain

P05230  (FGF1_HUMAN) -  Fibroblast growth factor 1 from Homo sapiens

Seq: 155 a.a.

Struc: 133 a.a.

Enzyme reactions

• Enzyme class: Chains A, B: E.C.?