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PDBsum entry 2j7x

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protein ligands Protein-protein interface(s) links
Transcription PDB id
2j7x
Jmol
Contents
Protein chains
228 a.a. *
11 a.a. *
Ligands
EST
EDO ×4
SO4
BCT
Waters ×98
* Residue conservation analysis
PDB id:
2j7x
Name: Transcription
Title: Structure of estradiol-bound estrogen receptor beta lbd in complex with lxxll motif from ncoa5
Structure: Estrogen receptor beta. Chain: a. Fragment: ligand-binding domain, residues 255-509. Synonym: er-beta. Engineered: yes. Nuclear receptor coactivator 5. Chain: b. Fragment: lxxll peptide, residues 338-354. Synonym: ncoa-5, coactivator independent of af-2, cia, ncoa
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606
Biol. unit: Dimer (from PDB file)
Resolution:
2.10Å     R-factor:   0.192     R-free:   0.234
Authors: A.C.W.Pike,A.M.Brzozowski,R.E.Hubbard,J.Walton,T.Bonn,A.-G.T O.Engstrom,J.Ljunggren,J.-A.Gustaffson,M.Carlquist
Key ref: A.C.W.Pike et al. Structure of agonist-Bound estrogen receptor beta lbd in complex with lxxll motif from ncoa5. To be published, .
Date:
17-Oct-06     Release date:   07-Nov-06    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q62986  (ESR2_RAT) -  Estrogen receptor beta
Seq:
Struc:
 
Seq:
Struc:
530 a.a.
228 a.a.
Protein chain
Pfam   ArchSchema ?
Q9HCD5  (NCOA5_HUMAN) -  Nuclear receptor coactivator 5
Seq:
Struc:
 
Seq:
Struc:
579 a.a.
11 a.a.
Key:    PfamA domain  PfamB domain  Secondary structure  CATH domain

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     nucleus   1 term 
  Biological process     steroid hormone mediated signaling pathway   2 terms 
  Biochemical function     DNA binding     3 terms