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PDBsum entry 2i42

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protein ligands links
Hydrolase PDB id
2i42
Jmol
Contents
Protein chain
282 a.a. *
Ligands
VO4
Waters ×183
* Residue conservation analysis
PDB id:
2i42
Name: Hydrolase
Title: Crystal structure of yersinia protein tyrosine phosphatasE C with vanadate, a transition state analogue
Structure: Tyrosine-protein phosphatase. Chain: a. Fragment: tyrosine-protein phosphatase. Synonym: virulence protein. Engineered: yes. Mutation: yes
Source: Yersinia enterocolitica. Organism_taxid: 630. Strain: w22703. Gene: yoph, yop51. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Resolution:
2.20Å     R-factor:   0.170    
Authors: J.Vijayalakshmi,M.A.Saper
Key ref: J.Vijayalakshmi and m.a.saper Crystal structure of yersinia protein tyrosine phosphatase complexed with vanadate, A transition state analogue. To be published, .
Date:
21-Aug-06     Release date:   19-Sep-06    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P15273  (YOPH_YEREN) -  Tyrosine-protein phosphatase YopH
Seq:
Struc:
468 a.a.
282 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

 Enzyme reactions 
   Enzyme class: E.C.3.1.3.48  - Protein-tyrosine-phosphatase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Protein tyrosine phosphate + H2O = protein tyrosine + phosphate
Protein tyrosine phosphate
+ H(2)O
= protein tyrosine
+ phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     dephosphorylation   2 terms 
  Biochemical function     phosphatase activity     2 terms