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PDBsum entry 2hq6

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protein ligands metals links
Isomerase PDB id
2hq6
Jmol
Contents
Protein chain
170 a.a. *
Ligands
GOL
Metals
IOD ×2
Waters ×175
* Residue conservation analysis
PDB id:
2hq6
Name: Isomerase
Title: Structure of the cyclophilin_cecyp16-like domain of the sero defined colon cancer antigen 10 from homo sapiens
Structure: Serologically defined colon cancer antigen 10. Chain: a. Fragment: cyclophilin_cecyp16-like domain (residues 8-173). Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: sdccag10. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Resolution:
1.75Å     R-factor:   0.167     R-free:   0.181
Authors: J.R.Walker,T.Davis,R.Paramanathan,E.M.Newman,P.J.Finerty Jr. F.Mackenzie,J.Weigelt,M.Sundstrom,C.H.Arrowsmith,A.M.Edward A.Bochkarev,S.Dhe-Paganon,Structural Genomics Consortium (S
Key ref: J.R.Walker et al. Structure of the cyclophilin_cecyp16-Like domain of the serologically defined colon cancer antigen 10. To be published, .
Date:
18-Jul-06     Release date:   01-Aug-06    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q6UX04  (CWC27_HUMAN) -  Peptidyl-prolyl cis-trans isomerase CWC27 homolog
Seq:
Struc:
472 a.a.
170 a.a.*
Key:    PfamA domain  PfamB domain  Secondary structure
* PDB and UniProt seqs differ at 5 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: E.C.5.2.1.8  - Peptidylprolyl isomerase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Peptidylproline (omega=180) = peptidylproline (omega=0)
Peptidylproline (omega=180)
= peptidylproline (omega=0)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     protein folding   2 terms 
  Biochemical function     peptidyl-prolyl cis-trans isomerase activity     1 term