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PDBsum entry 2hpc

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protein ligands metals Protein-protein interface(s) links
Blood clotting PDB id
2hpc
Jmol
Contents
Protein chains
74 a.a. *
307 a.a. *
305 a.a. *
79 a.a. *
Ligands
GLY-PRO-ARG-PRO-
NH2
×8
NDG ×2
NAG ×2
Metals
_CA ×10
* Residue conservation analysis
PDB id:
2hpc
Name: Blood clotting
Title: Crystal structure of fragment d from human fibrinogen comple gly-pro-arg-pro-amide.
Structure: Fibrinogen alpha chain. Chain: a, d, g, j. Fibrinogen beta chain. Chain: b, e, h, k. Fibrinogen, gamma polypeptide. Chain: c, f, i, l. Gly-pro-arg-pro-amide peptide ligand. Chain: m, n, o, p, q, r, s, t. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Synthetic: yes. Other_details: the peptide was chemically synthesized.
Resolution:
2.90Å     R-factor:   0.275     R-free:   0.360
Authors: R.F.Doolittle,J.M.Kollman,A.Chen,L.Pandi
Date:
17-Jul-06     Release date:   29-May-07    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
P02671  (FIBA_HUMAN) -  Fibrinogen alpha chain
Seq:
Struc:
 
Seq:
Struc:
866 a.a.
74 a.a.
Protein chains
Pfam   ArchSchema ?
P02675  (FIBB_HUMAN) -  Fibrinogen beta chain
Seq:
Struc:
491 a.a.
307 a.a.
Protein chains
Pfam   ArchSchema ?
P02679  (FIBG_HUMAN) -  Fibrinogen gamma chain
Seq:
Struc:
453 a.a.
305 a.a.
Protein chain
Pfam   ArchSchema ?
P02671  (FIBA_HUMAN) -  Fibrinogen alpha chain
Seq:
Struc:
 
Seq:
Struc:
866 a.a.
79 a.a.
Key:    PfamA domain  PfamB domain  Secondary structure  CATH domain

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     fibrinogen complex   1 term 
  Biological process     signal transduction   3 terms 
  Biochemical function     receptor binding     2 terms