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PDBsum entry 2he0

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protein ligands Protein-protein interface(s) links
Signaling protein PDB id
2he0
Jmol
Contents
Protein chain
195 a.a. *
Ligands
EDO
Waters ×416
* Residue conservation analysis
PDB id:
2he0
Name: Signaling protein
Title: Crystal structure of a human notch1 ankyrin domain mutant
Structure: Notch1 preproprotein variant. Chain: a, b. Fragment: ankyrin domain, residues 1873-2115. Synonym: human notch ankyrin domain mutant. Engineered: yes. Mutation: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: notch 1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
1.90Å     R-factor:   0.190     R-free:   0.231
Authors: D.Gupta,M.T.Ehebauer,D.Y.Chirgadze,A.Martinez Arias, T.L.Blundell
Key ref: D.Gupta et al. Crystal structure of a human notch1 ankyrin domain mutant. To be published, .
Date:
21-Jun-06     Release date:   04-Jul-06    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
P46531  (NOTC1_HUMAN) -  Neurogenic locus notch homolog protein 1
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
2555 a.a.
195 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 3 residue positions (black crosses)