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PDBsum entry 2hcu

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protein ligands links
Lyase PDB id
2hcu
Jmol
Contents
Protein chain
177 a.a. *
Ligands
SO4 ×3
Waters ×117
* Residue conservation analysis
PDB id:
2hcu
Name: Lyase
Title: Crystal structure of smu.1381 (or leud) from streptococcus mutans
Structure: 3-isopropylmalate dehydratase small subunit. Chain: a. Synonym: isopropylmalate isomerase, alpha-ipm isomerase, ipmi. Engineered: yes
Source: Streptococcus mutans. Organism_taxid: 1309. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Resolution:
2.10Å     R-factor:   0.189     R-free:   0.218
Authors: Z.Q.Gao,H.F.Hou,L.F.Li,Y.H.Liang,X.D.Su,Y.H.Dong
Key ref: Z.Q.Gao et al. Crystal structure of smu.1381 (or leud) from streptococcus mutans. To be published, .
Date:
19-Jun-06     Release date:   04-Jul-06    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q8DTG5  (LEUD_STRMU) -  3-isopropylmalate dehydratase small subunit
Seq:
Struc:
196 a.a.
177 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.4.2.1.33  - 3-isopropylmalate dehydratase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

      Pathway:
Leucine Biosynthesis
      Reaction: (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate
(2R,3S)-3-isopropylmalate
= (2S)-2-isopropylmalate
      Cofactor: Iron-sulfur
Iron-sulfur
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     3-isopropylmalate dehydratase complex   1 term 
  Biological process     metabolic process   5 terms 
  Biochemical function     lyase activity     4 terms