PDBsum entry: 2g17

Oxidoreductase

PDB id

2g17

Contents

			Protein chain

					337 a.a. *

			Ligands

					SO4 ×10

			Waters ×329

* Residue conservation analysis

PDB id:

2g17

Links
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Name:

Oxidoreductase

Title:

The structure of n-acetyl-gamma-glutamyl-phosphate reductase salmonella typhimurium.

Structure:

N-acetyl-gamma-glutamyl-phosphate reductase. Chain: a. Synonym: agpr, n- acetyl-glutamate semialdehyde dehydrogena dehydrogenase. Engineered: yes

Source:

Salmonella typhimurium. Organism_taxid: 99287. Strain: lt2. Gene: argc. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Biol. unit:

Tetramer (from PDB file)

Resolution:

2.30Å

R-factor:

0.171

R-free:

0.193

Authors:

M.E.Cuff,M.Zhou,J.Abdullah,A.Joachimiak,Midwest Center For S Genomics (Mcsg)

Key ref:

Midwest center for structural genomics (mcsg) The structure of n-Acetyl-Gamma-Glutamyl-Phosphate reductase from salmonella typhimurium.. To be published,

Date:

13-Feb-06

Release date:

21-Mar-06

PROCHECK

	Headers

	References

Protein chain

Q8ZKL8 (ARGC_SALTY) - N-acetyl-gamma-glutamyl-phosphate reductase

Seq: Struc:					334 a.a. 337 a.a.

Key:

PfamA domain

Secondary structure

CATH domain



		Enzyme reactions

Enzyme class:

E.C.1.2.1.38 - N-acetyl-gamma-glutamyl-phosphate reductase.

[IntEnz] [ExPASy] [KEGG] [BRENDA]

Pathway:

Ornithine Biosynthesis

Reaction:

N-acetyl-L-glutamate 5-semialdehyde + NADP⁺ + phosphate = N-acetyl-5- glutamyl phosphate + NADPH

N-acetyl-L-glutamate 5-semialdehyde	+	NADP(+)	+	phosphate	=	N-acetyl-5- glutamyl phosphate	+	NADPH

Molecule diagrams generated from .mol files obtained from the KEGG ftp site



		Gene Ontology (GO) functional annotation

Cellular component	cytoplasm	1 term
Biological process	oxidation-reduction process	4 terms
Biochemical function	nucleotide binding	6 terms