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PDBsum entry 2f0a

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protein ligands metals Protein-protein interface(s) links
Signaling protein PDB id
2f0a
Jmol
Contents
Protein chains
92 a.a. *
89 a.a. *
85 a.a. *
89 a.a. *
Ligands
SO4
Metals
_CO
Waters ×152
* Residue conservation analysis
PDB id:
2f0a
Name: Signaling protein
Title: Crystal structure of monomeric uncomplexed form of xenopus dishevelled pdz domain
Structure: Segment polarity protein dishevelled homolog dvl- 2. Chain: a, b, c, d. Fragment: dishevelled pdz domain. Synonym: dishevelled-2, dsh homolog 2, xdsh. Engineered: yes
Source: Xenopus laevis. African clawed frog. Organism_taxid: 8355. Gene: dvl2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Biol. unit: Tetramer (from PQS)
Resolution:
1.80Å     R-factor:   0.216     R-free:   0.253
Authors: N.Friedland,L.-W.Hung,B.Cheyette,R.T.Moon,T.N.Earnest
Key ref: N.Friedland et al. Conformational flexibility in the pdz domain of dishevelled induced by target binding. To be published, .
Date:
12-Nov-05     Release date:   22-Nov-05    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
P51142  (DVL2_XENLA) -  Segment polarity protein dishevelled homolog DVL-2
Seq:
Struc:
 
Seq:
Struc:
736 a.a.
92 a.a.*
Protein chain
Pfam   ArchSchema ?
P51142  (DVL2_XENLA) -  Segment polarity protein dishevelled homolog DVL-2
Seq:
Struc:
 
Seq:
Struc:
736 a.a.
89 a.a.*
Protein chain
Pfam   ArchSchema ?
P51142  (DVL2_XENLA) -  Segment polarity protein dishevelled homolog DVL-2
Seq:
Struc:
 
Seq:
Struc:
736 a.a.
85 a.a.*
Protein chain
Pfam   ArchSchema ?
P51142  (DVL2_XENLA) -  Segment polarity protein dishevelled homolog DVL-2
Seq:
Struc:
 
Seq:
Struc:
736 a.a.
89 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 20 residue positions (black crosses)

 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     multicellular organismal development   1 term 
  Biochemical function     signal transducer activity     1 term