PDBsum entry 2ets

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protein ligands metals links
Unknown function PDB id
Protein chain
115 a.a. *
_CL ×3
Waters ×55
* Residue conservation analysis
PDB id:
Name: Unknown function
Title: Crystal structure of a bacterial domain of unknown function duf1798 family (mw1337) from staphylococcus aureus subsp. A 2.25 a resolution
Structure: Hypothetical protein. Chain: a. Engineered: yes
Source: Staphylococcus aureus subsp. Aureus. Organism_taxid: 196620. Strain: mw2. Gene: np_646154.1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Biol. unit: Hexamer (from PQS)
2.25Å     R-factor:   0.175     R-free:   0.217
Authors: Joint Center For Structural Genomics (Jcsg)
Key ref:
P.Kozbial et al. (2008). Crystal structures of MW1337R and lin2004: representatives of a novel protein family that adopt a four-helical bundle fold. Proteins, 71, 1589-1596. PubMed id: 18324683 DOI: 10.1002/prot.22020
27-Oct-05     Release date:   08-Nov-05    
Go to PROCHECK summary

Protein chain
Pfam   ArchSchema ?
Q8NWP7  (Q8NWP7_STAAW) -  Uncharacterized protein
116 a.a.
115 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)


DOI no: 10.1002/prot.22020 Proteins 71:1589-1596 (2008)
PubMed id: 18324683  
Crystal structures of MW1337R and lin2004: representatives of a novel protein family that adopt a four-helical bundle fold.
P.Kozbial, Q.Xu, H.J.Chiu, D.McMullan, S.S.Krishna, M.D.Miller, P.Abdubek, C.Acosta, T.Astakhova, H.L.Axelrod, D.Carlton, T.Clayton, M.Deller, L.Duan, Y.Elias, M.A.Elsliger, J.Feuerhelm, S.K.Grzechnik, J.Hale, G.W.Han, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, E.Koesema, A.Kumar, D.Marciano, A.T.Morse, K.D.Murphy, E.Nigoghossian, L.Okach, S.Oommachen, R.Reyes, C.L.Rife, G.Spraggon, C.V.Trout, H.van den Bedem, D.Weekes, A.White, G.Wolf, C.Zubieta, K.O.Hodgson, J.Wooley, A.M.Deacon, A.Godzik, S.A.Lesley, I.A.Wilson.
No abstract given.

  Selected figure(s)  
Figure 1.
Figure 1. Crystal structure of MW1337R from Staphylococcus aureus subsp. aureus Rosenbach (Wood 46). A: Stereo ribbon diagram of the MW1337R monomer color-coded from N-terminus (blue) to C-terminus (red); -helices H1-H4 are indicated. B: Diagram showing the secondary structural elements of MW1337R superimposed on its primary sequence. Dashed lines indicate regions with no electron density, which are not included in the protein structure.
Figure 3.
Figure 3. Stereo view of structure superposition of MW1337R homologs. MW1337R (PDB code 2ets) is shown in green, lin2004 (PDB code 2huj) is shown in red, and yppE (PDB code 2im8) is shown in blue.
  The above figures are reprinted by permission from John Wiley & Sons, Inc.: Proteins (2008, 71, 1589-1596) copyright 2008.  
  Figures were selected by an automated process.