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PDBsum entry 2eoc

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protein links
Transferase PDB id
2eoc
Jmol
Contents
Protein chain
124 a.a. *
* Residue conservation analysis
PDB id:
2eoc
Name: Transferase
Title: Solution structure of the wgr domain from human poly [adp- ribose] polymerase-3
Structure: Poly [adp-ribose] polymerase 3. Chain: a. Fragment: wgr domain. Synonym: parp-3, NAD+, adp- ribosyltransferase 3, poly[adp- ribose] synthetase 3, padprt-3, hparp-3, irt1. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Other_details: cell-free protein synthesis
NMR struc: 20 models
Authors: T.Nagashima,F.Hayashi,S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)
Key ref: T.Nagashima et al. Solution structure of the wgr domain from human poly [adp-Ribose] polymerase-3. To be published, .
Date:
29-Mar-07     Release date:   01-Apr-08    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q9Y6F1  (PARP3_HUMAN) -  Poly [ADP-ribose] polymerase 3
Seq:
Struc:
 
Seq:
Struc:
533 a.a.
124 a.a.*
Key:    PfamA domain  Secondary structure
* PDB and UniProt seqs differ at 8 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: E.C.2.4.2.30  - NAD(+) ADP-ribosyltransferase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

      Pathway:
NAD+ ADP-ribosyltransferase
      Reaction: NAD+ + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D- ribosyl)(n+1)-acceptor
NAD(+)
+ (ADP-D-ribosyl)(n)-acceptor
= nicotinamide
+ (ADP-D- ribosyl)(n+1)-acceptor
Molecule diagrams generated from .mol files obtained from the KEGG ftp site