 |
|
|
|
|
|
 |
Contents |
 |
|
|
|
|
|
|
|
|
* Residue conservation analysis
|
|
|
|
|
|
PDB id:
|
|
|
|
| Name: |
|
Transferase
|
|
|
Title:
|
|
Solution structure of ruh-073, a pseudo chromo domain from human cdna
|
|
Structure:
|
|
Histone acetyltransferase htatip. Chain: a. Fragment: histone tail binding domain, pseudo chromo domain, unp residues 5-78. Synonym: 60 kda tat interactive protein, tip60, HIV-1 tat interactive protein, cpla(2)-interacting protein. Engineered: yes. Mutation: yes
|
|
Source:
|
|
Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: cell-free protein synthesis
|
|
NMR struc:
|
|
20 models
|
|
|
Authors:
|
|
A.Z.M.Ruhul Momen,H.Hirota,F.Hayashi,S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)
|
|
Key ref:
|
|
A.Z.M.Ruhul momen
et al.
Solution structure of ruh-073, A pseudo chromo domain from human cdna.
To be published,
|
|
|
Date:
|
|
|
23-Mar-07
|
Release date:
|
25-Sep-07
|
|
|
|
|
|
|
PROCHECK
|
|
|
|
|
|
Headers
|
|
|
|
References
|
|
|
|
|
|
|
|
|
|
|
|
Q92993
(KAT5_HUMAN) -
Histone acetyltransferase KAT5
|
|
|
|
Seq:
Struc:
|
|
|
|
513 a.a.
87 a.a.*
|
|
|
|
|
|
|
|
|
|
|
|
|
Key: |
 |
PfamA domain |
|
|
 |
Secondary structure |
|
|
*
PDB and UniProt seqs differ
at 11 residue positions (black
crosses)
|
|
|
|
|
|
|
|
|
|
|
|
|
Enzyme class:
|
|
E.C.2.3.1.48
- Histone acetyltransferase.
|
|
|
|
|
|
|
Reaction:
|
|
Acetyl-CoA + [histone] = CoA + acetyl-[histone]
|
|
|
|
|
|
Acetyl-CoA
|
+
|
[histone]
|
=
|
CoA
|
+
|
acetyl-[histone]
|
|
|
|
|
|
|
|
|
|
|
|
|
Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
|
|
|
|
|
|
|
|
|
|
|
Gene Ontology (GO) functional annotation
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Cellular component
|
nucleus
|
2 terms
|
|
|
Biological process
|
chromatin assembly or disassembly
|
1 term
|
|
|
Biochemical function
|
chromatin binding
|
1 term
|
|
|
|
|
|
|
|
|
|
|
Links
