PDBsum entry: 2eko

Transferase

PDB-id: 2eko

Contents

Description

Header details

Header records

References

PROCHECK

Protein chain

87 a.a. *

* Residue conservation analysis

Tools

Clefts Calculation

PDB id:

2eko

Name:

Transferase

Title:

Solution structure of ruh-073, a pseudo chromo domain from human cdna

Structure:

Histone acetyltransferase htatip. Chain: a. Fragment: histone tail binding domain, pseudo chromo domain, unp residues 5-78. Synonym: 60 kda tat interactive protein, tip60, HIV-1 tat interactive protein, cpla(2)-interacting protein. Engineered: yes. Mutation: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: cell-free protein synthesis

UniProt:

Q92993 (KAT5_HUMAN)

Seq:

Struc:

Seq:

513 a.a.

Struc:

87 a.a.*

Key:

PfamA domain

Secondary structure

* PDB and UniProt seqs differ at 11 residue positions (black crosses)

Enzyme class:

E.C.2.3.1.48   [IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

Reaction:

Acetyl-CoA + histone = CoA + acetylhistone (see diagram below)

Resolution:

not givenÅ

NMR structure:

20 models

Authors:

A.Z.M.Ruhul Momen,H.Hirota,F.Hayashi,S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)

Key ref:

a.z.m.ruhul momen et al. solution structure of ruh-073, a pseudo chromo domain from human cdna. TO BE PUBLISHED, .

Date:

23-Mar-07

Release date:

25-Sep-07

Related entries:

Hss001000479.1 related db: targetdb

Quick_links

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Clefts

Surface