PDBsum entry: 2ee1

Signaling protein

PDB id: 2ee1

Contents

Protein chain

64 a.a. *

* Residue conservation analysis

PDB id:

2ee1

Name:

Signaling protein

Title:

Solution structures of the chromo domain of human chromodomain helicase-DNA-binding protein 4

Structure:

Chromodomain helicase-DNA-binding protein 4. Chain: a. Fragment: chromo domain. Synonym: atp- dependent helicase chd4, chd-4, mi-2 autoantigen 218 kda protein, mi2-beta. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: chd4. Other_details: cell-free protein synthesis

NMR struc:

20 models

Authors:

M.Sato,N.Tochio,S.Koshiba,S.Watanabe,T.Harada,T.Kigawa, S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)

Key ref:

M.Sato et al. Solution structures of the chromo domain of human chromodomain helicase-Dna-Binding protein 4. To be published,

Date:

15-Feb-07 Release date: 21-Aug-07

Protein chain

Q14839  (CHD4_HUMAN) -  Chromodomain-helicase-DNA-binding protein 4

Seq: 1912 a.a.

Struc: 64 a.a.*

* PDB and UniProt seqs differ at 7 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.3.6.4.12 - Dna helicase.
• Reaction: ATP + H₂O = ADP + phosphate

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 Gene Ontology (GO) functional annotation 

• Cellular component: nucleus (2 terms)
• Biological process: chromatin assembly or disassembly (1 term)
• Biochemical function: chromatin binding (1 term)