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PDBsum entry 2e2w

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protein links
Ligase PDB id
2e2w
Jmol
Contents
Protein chain
113 a.a. *
* Residue conservation analysis
PDB id:
2e2w
Name: Ligase
Title: Solution structure of the first brct domain of human DNA ligase iv
Structure: DNA ligase 4. Chain: a. Fragment: brct domain. Synonym: DNA ligase iv, polydeoxyribonucleotide synthase [atp] 4. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: lig4. Other_details: cell-free protein synthesis
NMR struc: 20 models
Authors: T.Nagashima,F.Hayashi,S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)
Key ref: T.Nagashima et al. Solution structure of the first brct domain of human DNA ligase IV. To be published, .
Date:
17-Nov-06     Release date:   05-Dec-06    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P49917  (DNLI4_HUMAN) -  DNA ligase 4
Seq:
Struc:
 
Seq:
Struc:
911 a.a.
113 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 7 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: E.C.6.5.1.1  - Dna ligase (ATP).
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m)
ATP
+ (deoxyribonucleotide)(n)
+ (deoxyribonucleotide)(m)
= AMP
+ diphosphate
+ (deoxyribonucleotide)(n+m)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     DNA repair   2 terms 
  Biochemical function     DNA binding     3 terms