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* Residue conservation analysis
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PDB id:
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Cytokine
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Title:
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Solution structure of the irf domain of human interferon regulator factors 4
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Structure:
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Interferon regulatory factor 4. Chain: a. Fragment: irf domain, residues 8-115. Synonym: irf-4, lymphocyte-specific interferon regulatory factor, lsirf, nf-em5, multiple myeloma oncogene 1. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: irf4, mum1. Expressed in: cell free synthesis. Other_details: cell free protein synthesis
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NMR struc:
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20 models
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Authors:
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H.P.Zhang,C.Kurosaki,M.Yoshida,F.Hayashi,S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)
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Key ref:
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H.P.Zhang
et al.
Solution structure of the irf domain of human interferon regulator factors 4.
To be published,
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Date:
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20-Apr-06
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Release date:
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20-Oct-06
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PROCHECK
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Headers
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References
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Q15306
(IRF4_HUMAN) -
Interferon regulatory factor 4
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Seq: Struc:
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451 a.a.
121 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 9 residue positions (black
crosses)
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Gene Ontology (GO) functional annotation
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Biological process
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regulation of transcription, DNA-dependent
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1 term
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Biochemical function
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regulatory region DNA binding
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2 terms
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