PDBsum entry: 2dl6

Gene regulation

PDB id: 2dl6

Contents

Protein chain

83 a.a. *

* Residue conservation analysis

PDB id:

2dl6

Name:

Gene regulation

Title:

Solution structure of the first brk domain from human chromodomain-helicase-DNA-binding protein 8

Structure:

Chromodomain-helicase-DNA-binding protein 8. Chain: a. Fragment: brk domain. Synonym: atp-dependent helicase chd8, chd-8, helicase with snf2 domain 1. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: chd8, kiaa1564. Expressed in: cell free synthesis. Other_details: cell free protein synthesis

NMR struc:

20 models

Authors:

T.Suetake,T.Nagashima,F.Hayashi,S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)

Key ref:

T.Suetake et al. Solution structure of the first brk domain from human chromodomain-Helicase-Dna-Binding protein 8. To be published,

Date:

17-Apr-06 Release date: 17-Oct-06

Protein chain

Q9HCK8  (CHD8_HUMAN) -  Chromodomain-helicase-DNA-binding protein 8

Seq: 2581 a.a.

Struc: 83 a.a.*

* PDB and UniProt seqs differ at 13 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.3.6.4.12 - Dna helicase.
• Reaction: ATP + H₂O = ADP + phosphate

Molecule diagrams generated from .mol files obtained from the KEGG ftp site