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PDBsum entry 2dht

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protein Protein-protein interface(s) links
Oxidoreductase PDB id
2dht
Jmol
Contents
Protein chains
403 a.a. *
Waters ×38
* Residue conservation analysis
PDB id:
2dht
Name: Oxidoreductase
Title: Crystal structure of isocitrate dehydrogenase from sulfolobu strain7
Structure: 409aa long hypothetical NADP-dependent isocitrate dehydrogenase. Chain: a, b. Synonym: isocitrate dehydrogenase. Engineered: yes
Source: Sulfolobus tokodaii. Organism_taxid: 273063. Strain: str. 7. Expressed in: escherichia coli. Expression_system_taxid: 562
Resolution:
2.50Å     R-factor:   0.241     R-free:   0.272
Authors: H.Kondo,M.Murakami,K.Ihara,S.Suzuki,T.Kouyama
Key ref: H.Kondo et al. Crystal structure of isocitrate dehydrogenase of sulfolobus tokodaii strain7. To be published, .
Date:
25-Mar-06     Release date:   27-Mar-07    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q96YK6  (Q96YK6_SULTO) -  Isocitrate dehydrogenase
Seq:
Struc:
409 a.a.
403 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.1.1.1.42  - Isocitrate dehydrogenase (NADP(+)).
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

      Pathway:
Citric acid cycle
      Reaction: Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH
Isocitrate
+ NADP(+)
= 2-oxoglutarate
+ CO(2)
+ NADPH
      Cofactor: Mn(2+) or Mg(2+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     oxidation-reduction process   1 term 
  Biochemical function     nucleotide binding     6 terms