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PDBsum entry 2cz2

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protein ligands links
Isomerase, transferase PDB id
2cz2
Jmol
Contents
Protein chain
212 a.a. *
Ligands
GSH
GOL
Waters ×190
* Residue conservation analysis
PDB id:
2cz2
Name: Isomerase, transferase
Title: Crystal structure of glutathione transferase zeta 1-1 (maleylacetoacetate isomerase) from mus musculus (form-1 cr
Structure: Maleylacetoacetate isomerase. Chain: a. Synonym: glutathione transferase zeta 1-1 (maleylacetoaceta isomerase), maai, glutathione s-transferase zeta 1, gstz1-1 engineered: yes
Source: Mus musculus. House mouse. Organism_taxid: 10090. Other_details: cell-free protein synthesis
Biol. unit: Dimer (from PDB file)
Resolution:
1.40Å     R-factor:   0.157     R-free:   0.196
Authors: E.Mizohata,S.Morita,Y.Kinoshita,K.Nagano,H.Uda,T.Uchikubo,M. S.Yokoyama,Riken Structural Genomics/proteomics Initiative
Key ref: E.Mizohata et al. Crystal structure of glutathione transferase zeta 1-1 (maleylacetoacetate isomerase) from mus musculus (form-1 crystal). To be published, .
Date:
10-Jul-05     Release date:   10-Jan-06    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q9WVL0  (MAAI_MOUSE) -  Maleylacetoacetate isomerase
Seq:
Struc:
216 a.a.
212 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class 2: E.C.2.5.1.18  - Glutathione transferase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: RX + glutathione = HX + R-S-glutathione
RX
+
glutathione
Bound ligand (Het Group name = GSH)
corresponds exactly
= HX
+ R-S-glutathione
   Enzyme class 3: E.C.5.2.1.2  - Maleylacetoacetate isomerase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: 4-maleylacetoacetate = 4-fumarylacetoacetate
4-maleylacetoacetate
= 4-fumarylacetoacetate
Note, where more than one E.C. class is given (as above), each may correspond to a different protein domain or, in the case of polyprotein precursors, to a different mature protein.
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cytoplasm   2 terms 
  Biological process     metabolic process   5 terms 
  Biochemical function     catalytic activity     6 terms