PDBsum entry: 2cz0

Lyase

PDB id: 2cz0

Contents

Protein chains

197 a.a. *

211 a.a. *

Ligands

BUA

Metals

_FE

Waters ×391

* Residue conservation analysis

PDB id:

2cz0

Name:

Lyase

Title:

Photo-activation state of fe-type nhase in aerobic condition

Structure:

Nitrile hydratase subunit alpha. Chain: a. Synonym: nitrilase, nhase. Nitrile hydratase subunit beta. Chain: b. Synonym: nitrilase, nhase. Ec: 4.2.1.84

Source:

Rhodococcus erythropolis. Organism_taxid: 1833. Strain: n771. Strain: n771

Biol. unit:

Tetramer (from PQS)

Resolution:

1.50Å R-factor: 0.174 R-free: 0.214

Authors:

Y.Kawano,K.Hashimoto,M.Odaka,H.Nakayama,K.Takio,I.Endo, N.Kamiya,Riken Structural Genomics/proteomics Initiative (Rsgi)

Key ref:

Y.Kawano et al. Photo-Activation state of fe-Type nhase in aerobic condition. To be published,

Date:

09-Jul-05 Release date: 09-Jan-06

Protein chain

P13448  (NHAA_RHOER) -  Nitrile hydratase subunit alpha

Seq: 207 a.a.

Struc: 197 a.a.*

Protein chain

P13449  (NHAB_RHOER) -  Nitrile hydratase subunit beta

Seq: 212 a.a.

Struc: 211 a.a.

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

Enzyme reactions

• Enzyme class: Chains A, B: E.C.4.2.1.84 - Nitrile hydratase.
• Reaction: An aliphatic amide = a nitrile + H₂O

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 Gene Ontology (GO) functional annotation 

• Cellular component: plastid (1 term)
• Biological process: nitrogen compound metabolic process (2 terms)
• Biochemical function: catalytic activity (6 terms)