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PDBsum entry 2cuv

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protein ligands Protein-protein interface(s) links
Membrane protein/oxidoreductase PDB id
2cuv
Jmol
Contents
Protein chains
66 a.a.
69 a.a.
71 a.a.
13 a.a.
12 a.a.
11 a.a.
13 a.a.
Ligands
LEU-LEU-SER-TYR-
ALA-GLY-CY3
ARG-LEU-SER-ARG-
LEU-LEU-SER-TYR-
ALA
Waters ×345
Superseded by: 2v1s 2v1s
PDB id:
2cuv
Name: Membrane protein/oxidoreductase
Title: Crystal structure of disulfide bond tethered tom20- presequence complexes
Structure: Mitochondrial import receptor subunit tom20 homolog. Chain: a, b, c, d, e, f, g. Fragment: cytosolic domain. Synonym: mitochondrial 20 kda outer membrane protein, outer mitochondrial membrane receptor tom20. Engineered: yes. Mitochondrial aldehyde dehydrogenase. Chain: h, i, j, k, l, m, n.
Source: Rattus norvegicus. Rat. Gene: tomm20. Expressed in: escherichia coli. Synthetic: yes. Other_details: a presequence peptide derived from rat aldehyde dehydrogenase (aldh)
Biol. unit: 40mer (from PQS)
Resolution:
2.05Å     R-factor:   0.255     R-free:   0.312
Authors: T.Obita,M.Igura,T.Ose,T.Endo,K.Maenaka,D.Kohda
Key ref: T.Obita et al. Crystal structure of disulfide bond tethered tom20-Presequence complexes. To be published, .
Date:
29-May-05     Release date:   23-May-06    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q62760  (TOM20_RAT) -  Mitochondrial import receptor subunit TOM20 homolog
Seq:
Struc:
145 a.a.
66 a.a.
Protein chains
Pfam   ArchSchema ?
Q62760  (TOM20_RAT) -  Mitochondrial import receptor subunit TOM20 homolog
Seq:
Struc:
145 a.a.
69 a.a.*
Protein chain
Pfam   ArchSchema ?
Q62760  (TOM20_RAT) -  Mitochondrial import receptor subunit TOM20 homolog
Seq:
Struc:
145 a.a.
71 a.a.*
Protein chain
Pfam   ArchSchema ?
Q62760  (TOM20_RAT) -  Mitochondrial import receptor subunit TOM20 homolog
Seq:
Struc:
145 a.a.
13 a.a.
Protein chain
No UniProt id for this chain
Struc: 12 a.a.
Protein chains
No UniProt id for this chain
Struc: 11 a.a.
Protein chains
No UniProt id for this chain
Struc: 13 a.a.
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 4 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: Chain H: E.C.1.2.1.3  - Aldehyde dehydrogenase (NAD(+)).
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: An aldehyde + NAD+ + H2O = a carboxylate + NADH
aldehyde
+ NAD(+)
+ H(2)O
= carboxylate
+ NADH
Molecule diagrams generated from .mol files obtained from the KEGG ftp site