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Contents |
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* Residue conservation analysis
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PDB id:
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Transferase
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Title:
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Structure of human adenylate kinase 2
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Structure:
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Adenylate kinase isoenzyme 2, mitochondrial. Chain: a. Synonym: atp-amp transphosphorylase. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_cell_line: de3.
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Resolution:
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2.10Å
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R-factor:
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0.198
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R-free:
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0.274
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Authors:
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G.Bunkoczi,P.Filippakopoulos,J.E.Debreczeni,A.Turnbull, E.Papagrigoriou,P.Savitsky,S.Colebrook,F.Von Delft,C.Arrows A.Edwards,M.Sundstrom,J.Weigelt,S.Knapp
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Key ref:
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G.Bunkoczi
et al.
Structure of human adenylate kinase 2.
To be published,
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Date:
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15-Dec-05
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Release date:
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04-Jan-06
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PROCHECK
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Headers
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References
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P54819
(KAD2_HUMAN) -
Adenylate kinase 2, mitochondrial
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Seq:
Struc:
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239 a.a.
218 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Enzyme class:
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E.C.2.7.4.3
- Adenylate kinase.
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Reaction:
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ATP + AMP = 2 ADP
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ATP
Bound ligand (Het Group name = )
matches with 58.49% similarity
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+
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AMP
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=
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2
×
ADP
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Gene Ontology (GO) functional annotation
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Cellular component
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mitochondrion
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3 terms
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Biological process
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nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
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5 terms
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Biochemical function
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nucleotide binding
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8 terms
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Links
