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PDBsum entry 2bc0

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protein ligands Protein-protein interface(s) links
Oxidoreductase PDB id
2bc0
Jmol
Contents
Protein chains
473 a.a. *
Ligands
FAD ×2
Waters ×586
* Residue conservation analysis
PDB id:
2bc0
Name: Oxidoreductase
Title: Structural analysis of streptococcus pyogenes nadh oxidase: wild-type nox
Structure: Nadh oxidase. Chain: a, b. Engineered: yes
Source: Streptococcus pyogenes. Organism_taxid: 1314. Expressed in: escherichia coli. Expression_system_taxid: 562.
Biol. unit: Dimer (from PQS)
Resolution:
2.00Å     R-factor:   0.195     R-free:   0.234
Authors: W.H.Boles,T.C.Mallett
Key ref: T.C.Mallett et al. Structural analysis of streptococcus pyogenes nadh oxidase: conformational dynamics involved in formation of the c(4a)-Peroxyflavin intermediate. To be published, .
Date:
18-Oct-05     Release date:   31-Oct-06    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q5XC60  (NAOX_STRP6) -  Probable NADH oxidase
Seq:
Struc:
456 a.a.
473 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 3 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: E.C.1.6.99.3  - Nadh dehydrogenase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: NADH + acceptor = NAD+ + reduced acceptor
NADH
+ acceptor
= NAD(+)
+ reduced acceptor
      Cofactor: Flavoprotein; Iron-sulfur
Flavoprotein
Iron-sulfur
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     oxidation-reduction process   2 terms 
  Biochemical function     oxidoreductase activity     3 terms