PDBsum entry: 2a4d

Ligase

PDB id: 2a4d

Contents

Protein chain

139 a.a. *

Waters ×69

* Residue conservation analysis

PDB id:

2a4d

Name:

Ligase

Title:

Structure of the human ubiquitin-conjugating enzyme e2 variant 1 (uev-1)

Structure:

Ubiquitin-conjugating enzyme e2 variant 1. Chain: a. Fragment: catalytic domain, residues 82-220. Synonym: uev-1, croc-1, ubiquitin-conjugating enzyme variant kua, traf6-regulated ikk activator 1 beta uev1a, p/okcl.19. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2v1, croc1, ube2v, uev1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Biol. unit:

Dimer (from PQS)

Resolution:

1.69Å R-factor: 0.185 R-free: 0.240

Authors:

J.R.Walker,G.V.Avvakumov,S.Xue,E.M.Newman,F.Mackenzie, J.Weigelt,M.Sundstrom,C.Arrowsmith,A.Edwards,A.Bochkarev, S.Dhe-Paganon,Structural Genomics Consortium (Sgc)

Key ref:

J.R.Walker et al. Structure of the human ubiquitin-Conjugating enzyme e2 variant 1 (uev-1). To be published,

Date:

28-Jun-05 Release date: 12-Jul-05

Protein chain

Q13404  (UB2V1_HUMAN) -  Ubiquitin-conjugating enzyme E2 variant 1

Seq: 147 a.a.

Struc: 139 a.a.

 Gene Ontology (GO) functional annotation 

• Cellular component: ubiquitin conjugating enzyme complex (4 terms)
• Biological process: cell differentiation (8 terms)
• Biochemical function: protein binding (3 terms)