PDBsum entry: 2a1y

Oxidoreductase

PDB id

2a1y

Contents

			Protein chain

					301 a.a. *

			Ligands

					5GP

			Waters ×174

* Residue conservation analysis

PDB id:

2a1y

Links
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Name:

Oxidoreductase

Title:

Crystal structure of guac-gmp complex from bacillus anthraci a resolution.

Structure:

Gmp reductase. Chain: a. Synonym: guanosine 5'-monophosphate oxidoreductase, guanosi monophosphate reductase. Engineered: yes

Source:

Bacillus anthracis. Organism_taxid: 1392. Gene: guac. Expressed in: escherichia coli. Expression_system_taxid: 562.

Biol. unit:

Tetramer (from PDB file)

Resolution:

2.27Å

R-factor:

0.171

R-free:

0.246

Authors:

R.Grenha,V.M.Levdikov,E.V.Blagova,M.J.Fogg,J.A.Brannigan, A.J.Wilkinson,K.S.Wilson,Structural Proteomics In Europe (S

Key ref:

R.Grenha et al. Crystal structure of guac-Gmp complex from bacillus anthracis at 2.26 a resolution.. To be published,

Date:

21-Jun-05

Release date:

04-Jul-06

PROCHECK

	Headers

	References

Protein chain

Q81JJ9 (GUAC_BACAN) - GMP reductase

Seq: Struc:					327 a.a. 301 a.a.

Key:

PfamA domain

Secondary structure

CATH domain



		Enzyme reactions

Enzyme class:

E.C.1.7.1.7 - Gmp reductase.

[IntEnz] [ExPASy] [KEGG] [BRENDA]

Reaction:

Inosine 5'-phosphate + NH₃ + NADP⁺ = guanosine 5'-phosphate + NADPH

Inosine 5'-phosphate

NH(3)

NADP(+)

guanosine 5'-phosphate
Bound ligand (Het Group name = 5GP)
corresponds exactly

NADPH

Molecule diagrams generated from .mol files obtained from the KEGG ftp site



		Gene Ontology (GO) functional annotation

Biological process	metabolic process	4 terms
Biochemical function	catalytic activity	4 terms