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Hydrolase PDB-id
2wh7
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Protein chain
152 a.a.
Waters ×200
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PDB id: 2wh7
Name: Hydrolase
Title: The partial structure of a group a streptpcoccal phage- encoded tail fibre hyaluronate lyase hylp2

Structure:
Hyaluronidase-phage associated. Chain: a. Fragment: hyaluronate lyases fragment, residues 215-372. Synonym: hylp2. Engineered: yes

Source:
Streptococcus pyogenes. Organism_taxid: 1314. Strain: m1 gas sf370. Atcc: 700294. Expressed in: escherichia coli. Expression_system_taxid: 469008.

UniProt:
Q99ZZ7 (Q99ZZ7_STRP1) Pfam  
Seq:
Struc:
Seq: 372 a.a.
Struc: 152 a.a.
Key:    PfamA domain  PfamB domain
 Secondary structure

Enzyme class:
E.C.3.2.1.35   [IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

Reaction:
Random hydrolysis of 1->4-linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate.

Resolution:
1.60Å

R-factor:
0.214

R-free:
0.258

Authors:
C.Martinez-Fleites,G.W.Black,J.P.Turkenburg,N.L.Smith, E.J.Taylor

Date:
01-May-09

Release date:
01-Sep-09
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