PDBsum entry 2hpc

Blood clotting

PDB id: 2hpc

Contents

Protein chains

74 a.a. *

307 a.a. *

305 a.a. *

79 a.a. *

Ligands

GLY-PRO-ARG-PRO-NH2 ×8

NAG ×4

Metals

_CA ×10

* Residue conservation analysis

PDB id:

2hpc

Name:

Blood clotting

Title:

Crystal structure of fragment d from human fibrinogen complexed with gly-pro-arg-pro-amide.

Structure:

Fibrinogen alpha chain. Chain: a, d, g, j. Fibrinogen beta chain. Chain: b, e, h, k. Fibrinogen, gamma polypeptide. Chain: c, f, i, l. Gly-pro-arg-pro-amide peptide ligand. Chain: m, n, o, p, q, r, s, t. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Synthetic: yes. Other_details: the peptide was chemically synthesized.

Resolution:

2.90Å R-factor: 0.275 R-free: 0.360

Authors:

R.F.Doolittle,J.M.Kollman,A.Chen,L.Pandi

Date:

17-Jul-06 Release date: 29-May-07

Protein chains

P02671  (FIBA_HUMAN) -  Fibrinogen alpha chain from Homo sapiens

Seq: 866 a.a.

Struc: 74 a.a.

Protein chains

P02675  (FIBB_HUMAN) -  Fibrinogen beta chain from Homo sapiens

Seq: 491 a.a.

Struc: 307 a.a.

Protein chains

P02679  (FIBG_HUMAN) -  Fibrinogen gamma chain from Homo sapiens

Seq: 453 a.a.

Struc: 305 a.a.

Protein chain

P02671  (FIBA_HUMAN) -  Fibrinogen alpha chain from Homo sapiens

Seq: 866 a.a.

Struc: 79 a.a.