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PDBsum entry 1zep

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protein metals links
Hydrolase PDB id
1zep
Jmol
Contents
Protein chain
283 a.a.
Metals
_CL
Waters ×132
Superseded by: 2a8b 2a8b
PDB id:
1zep
Name: Hydrolase
Title: Crystal structure of the catalytic domain of human tyrosine phosphatase receptor, type r
Structure: Receptor-type tyrosine-protein phosphatase r. Chain: a. Fragment: catalytic domain residues 375-655. Synonym: protein-tyrosine phosphatase pcptp1, nc-ptpcom1, ch-1ptpase. Engineered: yes
Source: Homo sapiens. Human. Gene: ptprr, ecptp. Expressed in: escherichia coli.
Resolution:
2.30Å     R-factor:   0.195     R-free:   0.256
Authors: E.Ugochukwu,J.Eswaran,A.Barr,E.Longman,C.Arrowsmith, A.Edwards,M.Sundstrom,F.Von Delft,S.Knapp,Structural Genomics Consortium (Sgc)
Key ref: E.Ugochukwu et al. Crystal structure of the catalytic domain of human tyrosine phosphatase receptor, Type r. To be published, .
Date:
19-Apr-05     Release date:   26-Apr-05    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q15256  (PTPRR_HUMAN) -  Receptor-type tyrosine-protein phosphatase R
Seq:
Struc:
 
Seq:
Struc:
657 a.a.
283 a.a.*
Key:    PfamA domain  PfamB domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 2 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: E.C.3.1.3.48  - Protein-tyrosine-phosphatase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Protein tyrosine phosphate + H2O = protein tyrosine + phosphate
Protein tyrosine phosphate
+ H(2)O
= protein tyrosine
+ phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site