PDBsum entry: 1z2u

Ligase

PDB-id: 1z2u

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Protein chain

150 a.a. *

Ligands

BU3 ×2

UNX ×10

Metal ions

_CL ×6

_NA

Waters ×113

* Residue conservation analysis

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PDB id:

1z2u

Name:

Ligase

Title:

The 1.1a crystallographic structure of ubiquitin- conjugating enzyme (ubc-2) from caenorhabditis elegans: functional and evolutionary significance

Structure:

Ubiquitin-conjugating enzyme e2 2. Chain: a. Synonym: ubiquitin-protein ligase 2, ubiquitin carrier protein 2. Engineered: yes

Source:

Caenorhabditis elegans. Organism_taxid: 6239. Gene: ubc-2, let-70. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

UniProt:

P35129 (UBC2_CAEEL)

Seq:

147 a.a.

Struc:

150 a.a.

Key:	PfamA domain
Secondary structure	CATH domain

Enzyme class:

E.C.6.3.2.19   [IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

Reaction:

ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine (see diagram below)

Resolution:

1.10Å

R-factor:

0.131

R-free:

0.149

Authors:

J.A.Gavira,E.Digiamamarino,W.Tempel,Z.J.Liu,B.C.Wang, E.Meehan,J.D.Ng,Southeast Collaboratory For Structural Genomics (Secsg)

Key ref:

j.a.gavira et al. the 1.1a crystallographic structure of ubiquitin-conjugating enzyme (ubc-2) from caenorhabditis elegans: functional and evolutionary significance. TO BE PUBLISHED, .

Date:

09-Mar-05

Release date:

22-Mar-05

Related entries:

M7.1 related db: targetdb

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