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PDBsum entry 1yj6

Go to PDB code: 
protein ligands metals Protein-protein interface(s) links
Transferase PDB id
1yj6
Jmol
Contents
Protein chain
217 a.a. *
Ligands
GSH ×3
Metals
_ZN ×3
Waters ×106
* Residue conservation analysis
PDB id:
1yj6
Name: Transferase
Title: Crystal structure of human glutathione s-transferase m1a-1a complexed with glutathionyl-zinc-trihydroxide
Structure: Glutathione s-transferase mu 1. Chain: a, b, c. Synonym: gstm1-1, gst class-mu 1, gstm1a-1a, gstm1b-1b, hb subunit 4, gth4. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gstm1, gst1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Biol. unit: Dimer (from PDB file)
Resolution:
2.50Å     R-factor:   0.230     R-free:   0.264
Authors: Y.V.Patskovsky,L.N.Patskovska,I.Listowsky,S.C.Almo
Key ref: Y.V.Patskovsky et al. Human glutathione s-Transferase m1a-1a catalyzes formation of gsh-Metal complexes. To be published, .
Date:
13-Jan-05     Release date:   01-Feb-05    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
P09488  (GSTM1_HUMAN) -  Glutathione S-transferase Mu 1
Seq:
Struc:
218 a.a.
217 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.2.5.1.18  - Glutathione transferase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: RX + glutathione = HX + R-S-glutathione
RX
+
glutathione
Bound ligand (Het Group name = GSH)
corresponds exactly
= HX
+ R-S-glutathione
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cytoplasm   2 terms 
  Biological process     metabolic process   8 terms 
  Biochemical function     transferase activity     5 terms  

 

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