PDBsum entry: 1yir

Transferase

PDB id: 1yir

Contents

Protein chains

390 a.a. *

Ligands

SO4 ×12

Waters ×716

* Residue conservation analysis

PDB id:

1yir

Name:

Transferase

Title:

Crystal structure of a nicotinate phosphoribosyltransferase

Structure:

Nicotinate phosphoribosyltransferase 2. Chain: a, b, c, d. Synonym: naprtase 2. Engineered: yes

Source:

Pseudomonas aeruginosa. Organism_taxid: 287. Gene: pncb2. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

2.10Å R-factor: 0.213 R-free: 0.247

Authors:

J.Seetharaman,S.Swaminathan,S.K.Burley,New York Sgx Research Center For Structural Genomics (Nysgxrc)

Key ref:

J.Seetharaman and s.swaminathan Crystal structure of a nicotinate phosphoribosyltransferase. To be published,

Date:

12-Jan-05 Release date: 01-Feb-05

Protein chains

Q9HW26  (PNCB2_PSEAE) -  Nicotinate phosphoribosyltransferase 2

Seq: 398 a.a.

Struc: 390 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.2.4.2.11 - Nicotinate phosphoribosyltransferase.
• Reaction: Nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha- D-ribose 1-diphosphate

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 Gene Ontology (GO) functional annotation 

• Cellular component: cytoplasm (1 term)
• Biological process: pyridine nucleotide biosynthetic process (3 terms)
• Biochemical function: transferase activity (4 terms)