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PDBsum entry 1xx6

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protein ligands metals Protein-protein interface(s) links
Transferase PDB id
1xx6
Jmol
Contents
Protein chains
178 a.a. *
166 a.a. *
Ligands
ADP ×2
Metals
_ZN ×2
Waters ×171
* Residue conservation analysis
PDB id:
1xx6
Name: Transferase
Title: X-ray structure of clostridium acetobutylicum thymidine kina adp. Northeast structural genomics target car26.
Structure: Thymidine kinase. Chain: a, b. Engineered: yes
Source: Clostridium acetobutylicum. Organism_taxid: 272562. Strain: atcc 824. Expressed in: escherichia coli. Expression_system_taxid: 562.
Biol. unit: Tetramer (from PQS)
Resolution:
2.00Å     R-factor:   0.241     R-free:   0.266
Authors: A.P.Kuzin,M.Abashidze,F.Forouhar,S.M.Vorobiev,T.B.Acton,L.-C R.Xiao,G.T.Montelione,L.Tong,J.F.Hunt,Northeast Structural Consortium (Nesg)
Key ref: A.P.Kuzin et al. X-Ray structure of clostridium acetobutylicum thymidine kinase with adp. Northeast structural genomics target car26.. To be published, .
Date:
04-Nov-04     Release date:   21-Dec-04    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q97F65  (KITH_CLOAB) -  Thymidine kinase
Seq:
Struc:
195 a.a.
178 a.a.
Protein chain
Pfam   ArchSchema ?
Q97F65  (KITH_CLOAB) -  Thymidine kinase
Seq:
Struc:
195 a.a.
166 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: Chains A, B: E.C.2.7.1.21  - Thymidine kinase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: ATP + thymidine = ADP + thymidine 5'-phosphate
ATP
+ thymidine
=
ADP
Bound ligand (Het Group name = ADP)
corresponds exactly
+ thymidine 5'-phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cytoplasm   1 term 
  Biological process     DNA metabolic process   4 terms 
  Biochemical function     nucleotide binding     7 terms