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PDBsum entry 1xq7

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protein Protein-protein interface(s) links
Isomerase/immunosuppressant PDB id
1xq7
Jmol
Contents
Protein chains
166 a.a. *
11 a.a. *
Waters ×288
* Residue conservation analysis
PDB id:
1xq7
Name: Isomerase/immunosuppressant
Title: Cyclophilin from trypanosoma cruzi bound to cyclosporin a
Structure: Peptidyl-prolyl cis-trans isomerase. Chain: a, b, c. Synonym: ppiase, rotamase, cyclophilin a. Engineered: yes. Cyclosporin a. Chain: d, e, f. Synonym: cyclosporine, ciclosporin, ciclosporine. Engineered: yes
Source: Trypanosoma cruzi. Organism_taxid: 5693. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Tolypocladium inflatum 2. Organism_taxid: 29910
Resolution:
2.07Å     R-factor:   0.172     R-free:   0.235
Authors: J.M.Caruthers,W.G.J.Hol,Structural Genomics Of Pathogenic Pr Consortium (Sgpp)
Key ref: J.M.Caruthers et al. Cyclophilin from trypanosoma cruzi bound to cyclosporin a. To be published, .
Date:
11-Oct-04     Release date:   21-Dec-04    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q4DPB9  (Q4DPB9_TRYCC) -  Peptidyl-prolyl cis-trans isomerase
Seq:
Struc:
194 a.a.
166 a.a.*
Protein chains
No UniProt id for this chain
Struc: 11 a.a.
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

 Enzyme reactions 
   Enzyme class: Chains A, B, C: E.C.5.2.1.8  - Peptidylprolyl isomerase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Peptidylproline (omega=180) = peptidylproline (omega=0)
Peptidylproline (omega=180)
= peptidylproline (omega=0)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     protein folding   2 terms 
  Biochemical function     peptidyl-prolyl cis-trans isomerase activity     1 term