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PDBsum entry 1wt4

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protein Protein-protein interface(s) links
Protein transport/oxidoreductase PDB id
1wt4
Jmol
Contents
Protein chains
73 a.a.
68 a.a.
13 a.a.
Waters ×152
Superseded by: 2v1t 2v1t
PDB id:
1wt4
Name: Protein transport/oxidoreductase
Title: Crystal structure of rat tom20-aldh presequence complex
Structure: Mitochondrial import receptor subunit tom20 homolog. Chain: a, b. Fragment: cytosolic domain, limited proteolyzed fragment. Synonym: mitochondrial 20 kda outer membrane protein, outer mitochondrial membrane receptor tom20. Engineered: yes. Aldehyde dehydrogenase, mitochondrial. Chain: c, d.
Source: Rattus norvegicus. Rat. Expressed in: escherichia coli. Synthetic: yes. Other_details: aldh-pre sequence
Biol. unit: Dimer (from PQS)
Resolution:
1.90Å     R-factor:   0.184     R-free:   0.242
Authors: T.Obita,M.Igura,T.Ose,T.Endo,K.Maenaka,D.Kohda
Key ref: T.Obita et al. Crystal structure of rat tom20-Aldh presequence complex. To be published, .
Date:
15-Nov-04     Release date:   22-Nov-05    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q62760  (TOM20_RAT) -  Mitochondrial import receptor subunit TOM20 homolog
Seq:
Struc:
145 a.a.
73 a.a.*
Protein chain
Pfam   ArchSchema ?
Q62760  (TOM20_RAT) -  Mitochondrial import receptor subunit TOM20 homolog
Seq:
Struc:
145 a.a.
68 a.a.
Protein chains
Pfam   ArchSchema ?
P11884  (ALDH2_RAT) -  Aldehyde dehydrogenase, mitochondrial
Seq:
Struc:
519 a.a.
13 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 7 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: Chains C, D: E.C.1.2.1.3  - Aldehyde dehydrogenase (NAD(+)).
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: An aldehyde + NAD+ + H2O = a carboxylate + NADH
aldehyde
+ NAD(+)
+ H(2)O
= carboxylate
+ NADH
Molecule diagrams generated from .mol files obtained from the KEGG ftp site