PDBsum entry: 1wkk

Transferase

PDB id: 1wkk

Contents

Protein chains

137 a.a. *

Ligands

GDP

Waters ×49

* Residue conservation analysis

PDB id:

1wkk

Name:

Transferase

Title:

Crystal structure of nucleoside diphosphate kinase from thermus thermophilus hb8 in complex with gdp

Structure:

Nucleoside diphosphate kinase. Chain: a, b. Engineered: yes

Source:

Thermus thermophilus. Organism_taxid: 274. Gene: ndk. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Biol. unit:

Hexamer (from PDB file)

Resolution:

2.70Å R-factor: 0.201 R-free: 0.240

Authors:

S.Takeishi,N.Nakagawa,R.Masui,S.Kuramitsu,Riken Structural Genomics/proteomics Initiative (Rsgi)

Key ref:

S.Takeishi et al. Crystal structure of nucleoside diphosphate kinase from thermus thermophilus hb8. To be published,

Date:

01-Jun-04 Release date: 23-Aug-05

Protein chains

Q5SLV5  (NDK_THET8) -  Nucleoside diphosphate kinase

Seq: 137 a.a.

Struc: 137 a.a.

Enzyme reactions

• Enzyme class: E.C.2.7.4.6 - Nucleoside-diphosphate kinase.
• Reaction: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate

ATP + nucleoside diphosphate = ADP (Bound ligand (Het Group name = GDP) matches with 96.00% similarity) + nucleoside triphosphate

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 Gene Ontology (GO) functional annotation 

• Cellular component: cytoplasm (1 term)
• Biological process: nucleotide metabolic process (4 terms)
• Biochemical function: nucleotide binding (6 terms)