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PDBsum entry 1vlh

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protein ligands Protein-protein interface(s) links
Transferase PDB id
1vlh
Jmol
Contents
Protein chains
(+ 0 more) 157 a.a. *
Ligands
PNS ×6
MPD
Waters ×258
* Residue conservation analysis
PDB id:
1vlh
Name: Transferase
Title: Crystal structure of phosphopantetheine adenylyltransferase from thermotoga maritima at 2.20 a resolution
Structure: Phosphopantetheine adenylyltransferase. Chain: a, b, c, d, e, f. Synonym: pantetheine-phosphate adenylyltransferase, ppat, d coa pyrophosphorylase. Engineered: yes
Source: Thermotoga maritima. Organism_taxid: 2336. Gene: coad, kdtb, tm0741. Expressed in: escherichia coli. Expression_system_taxid: 562.
Biol. unit: Hexamer (from PQS)
Resolution:
2.20Å     R-factor:   0.173     R-free:   0.227
Authors: Joint Center For Structural Genomics (Jcsg)
Key ref: Joint center for structural genomics (jcsg) Crystal structure of phosphopantetheine adenylyltransferase (tm0741) from thermotoga maritima at 2.20 a resolution. To be published, .
Date:
23-Jul-04     Release date:   17-Aug-04    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q9WZK0  (COAD_THEMA) -  Phosphopantetheine adenylyltransferase
Seq:
Struc:
161 a.a.
157 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.2.7.7.3  - Pantetheine-phosphate adenylyltransferase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

      Pathway:
Coenzyme A Biosynthesis (late stages)
      Reaction: ATP + pantetheine 4'-phosphate = diphosphate + 3'-dephospho-CoA
ATP
+
pantetheine 4'-phosphate
Bound ligand (Het Group name = PNS)
corresponds exactly
= diphosphate
+ 3'-dephospho-CoA
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cytoplasm   1 term 
  Biological process     biosynthetic process   2 terms 
  Biochemical function     catalytic activity     6 terms